ID   LIGV1_LIGVU             Reviewed;         145 AA.
AC   O82015; O82016;
DT   20-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   20-JUN-2001, sequence version 2.
DT   03-AUG-2022, entry version 67.
DE   RecName: Full=Major pollen allergen Lig v 1;
DE   AltName: Allergen=Lig v 1;
OS   Ligustrum vulgare (Common privet) (Ligustrum insulare).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Lamiales; Oleaceae; Oleeae; Ligustrum.
OX   NCBI_TaxID=13597;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND PARTIAL PROTEIN SEQUENCE.
RC   TISSUE=Pollen;
RX   PubMed=9027441; DOI=10.1111/j.1365-2222.1996.tb00542.x;
RA   Batanero E., Gonzalez de la Pena M., Villalba M., Monsalve R.I.,
RA   Martin-Esteban M., Rodriguez R.;
RT   "Isolation, cDNA cloning and expression of Lig v 1, the major allergen from
RT   privet pollen.";
RL   Clin. Exp. Allergy 26:1401-1410(1996).
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- ALLERGEN: Causes an allergic reaction in human.
CC   -!- SIMILARITY: Belongs to the Ole e I family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X77787; CAA54818.1; -; mRNA.
DR   EMBL; X77788; CAA54819.1; -; mRNA.
DR   PDB; 6YOA; X-ray; 2.83 A; A/B=1-145.
DR   PDBsum; 6YOA; -.
DR   AlphaFoldDB; O82015; -.
DR   SMR; O82015; -.
DR   Allergome; 446; Lig v 1.
DR   Allergome; 447; Lig v 1.0101.
DR   Allergome; 448; Lig v 1.0102.
DR   GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR   InterPro; IPR006040; Allergen_Ole_e_I_CS.
DR   InterPro; IPR006041; Pollen_Ole_e1_allergen.
DR   PANTHER; PTHR31614; PTHR31614; 1.
DR   PROSITE; PS00925; OLEEI; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Allergen; Direct protein sequencing; Disulfide bond;
KW   Glycoprotein; Secreted.
FT   CHAIN           1..145
FT                   /note="Major pollen allergen Lig v 1"
FT                   /id="PRO_0000215114"
FT   CARBOHYD        111
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        19..90
FT                   /evidence="ECO:0000250"
FT   DISULFID        22..131
FT                   /evidence="ECO:0000250"
FT   DISULFID        43..78
FT                   /evidence="ECO:0000250"
FT   VARIANT         51
FT                   /note="V -> I (in Lig v 1.0102)"
FT   VARIANT         60
FT                   /note="K -> R (in Lig v 1.0102)"
FT   VARIANT         66
FT                   /note="N -> S (in Lig v 1.0102)"
FT   VARIANT         83
FT                   /note="I -> L (in Lig v 1.0102)"
FT   VARIANT         95
FT                   /note="T -> I (in Lig v 1.0102)"
FT   VARIANT         106
FT                   /note="V -> M (in Lig v 1.0102)"
FT   VARIANT         123
FT                   /note="L -> F (in Lig v 1.0102)"
FT   VARIANT         127
FT                   /note="V -> A (in Lig v 1.0102)"
FT   STRAND          11..20
FT                   /evidence="ECO:0007829|PDB:6YOA"
FT   STRAND          38..49
FT                   /evidence="ECO:0007829|PDB:6YOA"
FT   STRAND          51..59
FT                   /evidence="ECO:0007829|PDB:6YOA"
FT   HELIX           61..63
FT                   /evidence="ECO:0007829|PDB:6YOA"
FT   STRAND          64..69
FT                   /evidence="ECO:0007829|PDB:6YOA"
FT   STRAND          74..84
FT                   /evidence="ECO:0007829|PDB:6YOA"
FT   STRAND          103..108
FT                   /evidence="ECO:0007829|PDB:6YOA"
FT   STRAND          114..116
FT                   /evidence="ECO:0007829|PDB:6YOA"
FT   STRAND          120..123
FT                   /evidence="ECO:0007829|PDB:6YOA"
FT   HELIX           131..137
FT                   /evidence="ECO:0007829|PDB:6YOA"
SQ   SEQUENCE   145 AA;  16400 MW;  A1DA057742BC7F5E CRC64;
     EDVPQPPVSQ FYIQGQVYCD TCRARFITEL SEFIPGAGVR LQCKDGENGK VTFTEVGYTK
     AEGLYNMLIE RDHKNEFCEI TLISSSRKDC DEIPTEGWVK PSLKFVLNTV NGTTRTINPL
     GFLKKEVLPK CPQVFNKLGM YPPNM