ID   LIN52_PONAB             Reviewed;         114 AA.
AC   Q5NVP8;
DT   03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   04-JAN-2005, sequence version 1.
DT   03-AUG-2022, entry version 57.
DE   RecName: Full=Protein lin-52 homolog;
GN   Name=LIN52;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain cortex;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Component of the DREAM complex (also named LINC complex) at
CC       least composed of E2F4, E2F5, LIN9, LIN37, LIN52, LIN54, MYBL1, MYBL2,
CC       RBL1, RBL2, RBBP4, TFDP1 and TFDP2. The complex exists in quiescent
CC       cells where it represses cell cycle-dependent genes. It dissociates in
CC       S phase when LIN9, LIN37, LIN52 and LIN54 form a subcomplex that binds
CC       to MYBL2 (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the lin-52 family. {ECO:0000305}.
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DR   EMBL; CR925964; CAI29615.1; -; mRNA.
DR   RefSeq; NP_001127075.1; NM_001133603.1.
DR   AlphaFoldDB; Q5NVP8; -.
DR   SMR; Q5NVP8; -.
DR   STRING; 9601.ENSPPYP00000006800; -.
DR   GeneID; 100174105; -.
DR   KEGG; pon:100174105; -.
DR   CTD; 91750; -.
DR   eggNOG; KOG4402; Eukaryota.
DR   HOGENOM; CLU_143062_1_0_1; -.
DR   InParanoid; Q5NVP8; -.
DR   OrthoDB; 1513733at2759; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0070176; C:DRM complex; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR018737; DREAM_LIN52.
DR   PANTHER; PTHR31489; PTHR31489; 1.
DR   Pfam; PF10044; LIN52; 1.
PE   3: Inferred from homology;
KW   Phosphoprotein; Reference proteome.
FT   CHAIN           1..114
FT                   /note="Protein lin-52 homolog"
FT                   /id="PRO_0000252156"
FT   MOD_RES         26
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q52LA3"
FT   MOD_RES         51
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q52LA3"
SQ   SEQUENCE   114 AA;  12843 MW;  51516ABBEB6605D6 CRC64;
     MGWKMASPTD DLEASLLSFE KLDRASPDLW PEQLPGVAEF AASFKSPITS SPPKWMAEIE
     RDDIDMLKEL GSLTTANLME KVRGLQNLAY QLGLDESREM TRGKFLNILE KPKK