ID   LIVF_SALTI              Reviewed;         237 AA.
AC   P0A192; P30294;
DT   01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=High-affinity branched-chain amino acid transport ATP-binding protein LivF;
DE   AltName: Full=LIV-I protein F;
GN   Name=livF; Synonyms=livG; OrderedLocusNames=STY4252, t3962;
OS   Salmonella typhi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT18;
RX   PubMed=11677608; DOI=10.1038/35101607;
RA   Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA   Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA   Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA   Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA   Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA   Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA   Barrell B.G.;
RT   "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT   serovar Typhi CT18.";
RL   Nature 413:848-852(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2;
RX   PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA   Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA   Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT   "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT   CT18.";
RL   J. Bacteriol. 185:2330-2337(2003).
CC   -!- FUNCTION: Component of the high-affinity branched-chain amino acid
CC       transport system. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AL513382; CAD08070.1; -; Genomic_DNA.
DR   EMBL; AE014613; AAO71432.1; -; Genomic_DNA.
DR   RefSeq; NP_458360.1; NC_003198.1.
DR   RefSeq; WP_000416114.1; NZ_WSUR01000001.1.
DR   AlphaFoldDB; P0A192; -.
DR   SMR; P0A192; -.
DR   STRING; 220341.16505049; -.
DR   EnsemblBacteria; AAO71432; AAO71432; t3962.
DR   KEGG; stt:t3962; -.
DR   KEGG; sty:STY4252; -.
DR   PATRIC; fig|220341.7.peg.4342; -.
DR   eggNOG; COG0410; Bacteria.
DR   HOGENOM; CLU_000604_1_2_6; -.
DR   OMA; IMMQKIM; -.
DR   Proteomes; UP000000541; Chromosome.
DR   Proteomes; UP000002670; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0015658; F:branched-chain amino acid transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR030660; ABC_branched_ATPase_LivF/BraG.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 1.
DR   PIRSF; PIRSF039137; ABC_branched_ATPase; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE   3: Inferred from homology;
KW   Amino-acid transport; ATP-binding; Nucleotide-binding; Transport.
FT   CHAIN           1..237
FT                   /note="High-affinity branched-chain amino acid transport
FT                   ATP-binding protein LivF"
FT                   /id="PRO_0000092402"
FT   DOMAIN          6..237
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         38..45
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ   SEQUENCE   237 AA;  26282 MW;  09297DC5CC6521D7 CRC64;
     MEKTMLTFEK VSAHYGKIQA LHDVSLHINQ GEIVTLIGAN GAGKTTLLGT LCGDPRASSG
     RVVFDGKDIT DWQTAKIMRE AVAIVPEGRR VFSRMTVEEN LAMGGFFAER DRFQERIKWV
     YELFPRLHER RIQRAGTMSG GEQQMLAIGR ALMSQPRLLL LDEPSLGLAP IIIQQIFDTI
     EQLREQGMTI FLVEQNANQA LKLADRGYVL ENGHVVLSDT GDALLANEAV RSAYLGG