ID   LIVF_SALTY              Reviewed;         237 AA.
AC   P0A191; P30294;
DT   01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 85.
DE   RecName: Full=High-affinity branched-chain amino acid transport ATP-binding protein LivF;
DE   AltName: Full=LIV-I protein F;
GN   Name=livF; Synonyms=livG; OrderedLocusNames=STM3560;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=LT2;
RX   PubMed=1429514; DOI=10.1093/oxfordjournals.jbchem.a123872;
RA   Matsubara K., Ohnishi K., Kiritani K.;
RT   "Nucleotide sequences and characterization of liv genes encoding components
RT   of the high-affinity branched-chain amino acid transport system in
RT   Salmonella typhimurium.";
RL   J. Biochem. 112:93-101(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
CC   -!- FUNCTION: Component of the high-affinity branched-chain amino acid
CC       transport system.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
CC   -!- CAUTION: Called LivG in S.typhimurium, but we renamed it to LivF for
CC       the sake of consistency with the E.coli protein. {ECO:0000305}.
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DR   EMBL; D12589; BAA02132.1; -; Genomic_DNA.
DR   EMBL; AE006468; AAL22420.1; -; Genomic_DNA.
DR   PIR; JH0671; JH0671.
DR   RefSeq; NP_462461.1; NC_003197.2.
DR   RefSeq; WP_000416114.1; NC_003197.2.
DR   AlphaFoldDB; P0A191; -.
DR   SMR; P0A191; -.
DR   STRING; 99287.STM3560; -.
DR   PaxDb; P0A191; -.
DR   EnsemblBacteria; AAL22420; AAL22420; STM3560.
DR   GeneID; 1255083; -.
DR   KEGG; stm:STM3560; -.
DR   PATRIC; fig|99287.12.peg.3763; -.
DR   HOGENOM; CLU_000604_1_2_6; -.
DR   OMA; IMMQKIM; -.
DR   PhylomeDB; P0A191; -.
DR   BioCyc; SENT99287:STM3560-MON; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0015658; F:branched-chain amino acid transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015807; P:L-amino acid transport; IBA:GO_Central.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR030660; ABC_branched_ATPase_LivF/BraG.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 1.
DR   PIRSF; PIRSF039137; ABC_branched_ATPase; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE   3: Inferred from homology;
KW   Amino-acid transport; ATP-binding; Nucleotide-binding; Reference proteome;
KW   Transport.
FT   CHAIN           1..237
FT                   /note="High-affinity branched-chain amino acid transport
FT                   ATP-binding protein LivF"
FT                   /id="PRO_0000092403"
FT   DOMAIN          6..237
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         38..45
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ   SEQUENCE   237 AA;  26282 MW;  09297DC5CC6521D7 CRC64;
     MEKTMLTFEK VSAHYGKIQA LHDVSLHINQ GEIVTLIGAN GAGKTTLLGT LCGDPRASSG
     RVVFDGKDIT DWQTAKIMRE AVAIVPEGRR VFSRMTVEEN LAMGGFFAER DRFQERIKWV
     YELFPRLHER RIQRAGTMSG GEQQMLAIGR ALMSQPRLLL LDEPSLGLAP IIIQQIFDTI
     EQLREQGMTI FLVEQNANQA LKLADRGYVL ENGHVVLSDT GDALLANEAV RSAYLGG