LIVG_METJA
ID LIVG_METJA Reviewed; 257 AA.
AC Q58663;
DT 26-SEP-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 132.
DE RecName: Full=Probable branched-chain amino acid transport ATP-binding protein LivG;
GN Name=livG; OrderedLocusNames=MJ1267;
OS Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS 10045 / NBRC 100440) (Methanococcus jannaschii).
OC Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC Methanocaldococcaceae; Methanocaldococcus.
OX NCBI_TaxID=243232;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT jannaschii.";
RL Science 273:1058-1073(1996).
RN [2]
RP X-RAY CRYSTALLOGRAPHY (1.6 ANGSTROMS).
RX PubMed=11470432; DOI=10.1016/s0969-2126(01)00617-7;
RA Karpowich N., Martsinkevich O., Millen L., Yuan Y.-R., Dai P.L., MacVey K.,
RA Thomas P.J., Hunt J.F.;
RT "Crystal structures of the MJ1267 ATP binding cassette reveal an induced-
RT fit effect at the ATPase active site of an ABC transporter.";
RL Structure 9:571-586(2001).
CC -!- FUNCTION: Probable component of a branched-chain amino-acid transport
CC system.
CC -!- SUBUNIT: Monomer.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
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DR EMBL; L77117; AAB99273.1; -; Genomic_DNA.
DR PIR; B64458; B64458.
DR PDB; 1G6H; X-ray; 1.60 A; A=1-257.
DR PDB; 1G9X; X-ray; 2.60 A; A/B/C=1-257.
DR PDB; 1GAJ; X-ray; 2.50 A; A=1-257.
DR PDBsum; 1G6H; -.
DR PDBsum; 1G9X; -.
DR PDBsum; 1GAJ; -.
DR AlphaFoldDB; Q58663; -.
DR BMRB; Q58663; -.
DR SMR; Q58663; -.
DR STRING; 243232.MJ_1267; -.
DR EnsemblBacteria; AAB99273; AAB99273; MJ_1267.
DR KEGG; mja:MJ_1267; -.
DR eggNOG; arCOG00925; Archaea.
DR HOGENOM; CLU_000604_1_2_2; -.
DR InParanoid; Q58663; -.
DR OMA; EHDMRFI; -.
DR PhylomeDB; Q58663; -.
DR EvolutionaryTrace; Q58663; -.
DR Proteomes; UP000000805; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Amino-acid transport; ATP-binding; Nucleotide-binding;
KW Reference proteome; Transport.
FT CHAIN 1..257
FT /note="Probable branched-chain amino acid transport ATP-
FT binding protein LivG"
FT /id="PRO_0000092412"
FT DOMAIN 8..253
FT /note="ABC transporter"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT BINDING 40..47
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT STRAND 6..17
FT /evidence="ECO:0007829|PDB:1G6H"
FT STRAND 20..26
FT /evidence="ECO:0007829|PDB:1G6H"
FT STRAND 29..31
FT /evidence="ECO:0007829|PDB:1G6H"
FT STRAND 35..39
FT /evidence="ECO:0007829|PDB:1G6H"
FT HELIX 46..53
FT /evidence="ECO:0007829|PDB:1G6H"
FT STRAND 60..66
FT /evidence="ECO:0007829|PDB:1G6H"
FT HELIX 76..82
FT /evidence="ECO:0007829|PDB:1G6H"
FT STRAND 84..86
FT /evidence="ECO:0007829|PDB:1G6H"
FT HELIX 92..96
FT /evidence="ECO:0007829|PDB:1G6H"
FT HELIX 99..104
FT /evidence="ECO:0007829|PDB:1G6H"
FT HELIX 105..107
FT /evidence="ECO:0007829|PDB:1G6H"
FT HELIX 114..120
FT /evidence="ECO:0007829|PDB:1G6H"
FT HELIX 128..140
FT /evidence="ECO:0007829|PDB:1G6H"
FT HELIX 144..146
FT /evidence="ECO:0007829|PDB:1G6H"
FT HELIX 151..153
FT /evidence="ECO:0007829|PDB:1G6H"
FT HELIX 156..169
FT /evidence="ECO:0007829|PDB:1G6H"
FT STRAND 173..179
FT /evidence="ECO:0007829|PDB:1G6H"
FT TURN 180..183
FT /evidence="ECO:0007829|PDB:1G6H"
FT HELIX 186..201
FT /evidence="ECO:0007829|PDB:1G6H"
FT STRAND 205..209
FT /evidence="ECO:0007829|PDB:1G6H"
FT HELIX 213..216
FT /evidence="ECO:0007829|PDB:1GAJ"
FT HELIX 217..219
FT /evidence="ECO:0007829|PDB:1G6H"
FT STRAND 221..227
FT /evidence="ECO:0007829|PDB:1G6H"
FT STRAND 230..237
FT /evidence="ECO:0007829|PDB:1G6H"
FT HELIX 238..246
FT /evidence="ECO:0007829|PDB:1G6H"
FT HELIX 248..252
FT /evidence="ECO:0007829|PDB:1G6H"
FT TURN 253..256
FT /evidence="ECO:0007829|PDB:1G6H"
SQ SEQUENCE 257 AA; 28995 MW; B3347C3277D09C12 CRC64;
MRDTMEILRT ENIVKYFGEF KALDGVSISV NKGDVTLIIG PNGSGKSTLI NVITGFLKAD
EGRVYFENKD ITNKEPAELY HYGIVRTFQT PQPLKEMTVL ENLLIGEINP GESPLNSLFY
KKWIPKEEEM VEKAFKILEF LKLSHLYDRK AGELSGGQMK LVEIGRALMT NPKMIVMDEP
IAGVAPGLAH DIFNHVLELK AKGITFLIIE HRLDIVLNYI DHLYVMFNGQ IIAEGRGEEE
IKNVLSDPKV VEIYIGE
