LIVG_SALTY
ID LIVG_SALTY Reviewed; 255 AA.
AC P0A193; P30293;
DT 01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2005, sequence version 1.
DT 03-AUG-2022, entry version 83.
DE RecName: Full=High-affinity branched-chain amino acid transport ATP-binding protein LivG;
DE AltName: Full=LIV-I protein G;
GN Name=livG; Synonyms=livF; OrderedLocusNames=STM3561;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=LT2;
RX PubMed=1429514; DOI=10.1093/oxfordjournals.jbchem.a123872;
RA Matsubara K., Ohnishi K., Kiritani K.;
RT "Nucleotide sequences and characterization of liv genes encoding components
RT of the high-affinity branched-chain amino acid transport system in
RT Salmonella typhimurium.";
RL J. Biochem. 112:93-101(1992).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
CC -!- FUNCTION: Component of the high-affinity branched-chain amino acid
CC transport system.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
CC -!- CAUTION: Called LivF in S.typhimurium, but we renamed it to LivG for
CC the sake of consistency with the E.coli protein. {ECO:0000305}.
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DR EMBL; D12589; BAA02131.1; -; Genomic_DNA.
DR EMBL; AE006468; AAL22421.1; -; Genomic_DNA.
DR PIR; JH0670; JH0670.
DR RefSeq; NP_462462.1; NC_003197.2.
DR RefSeq; WP_000082083.1; NC_003197.2.
DR AlphaFoldDB; P0A193; -.
DR SMR; P0A193; -.
DR STRING; 99287.STM3561; -.
DR PaxDb; P0A193; -.
DR EnsemblBacteria; AAL22421; AAL22421; STM3561.
DR GeneID; 1255084; -.
DR KEGG; stm:STM3561; -.
DR PATRIC; fig|99287.12.peg.3764; -.
DR HOGENOM; CLU_000604_1_2_6; -.
DR OMA; EHDMRFI; -.
DR PhylomeDB; P0A193; -.
DR BioCyc; SENT99287:STM3561-MON; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0015188; F:L-isoleucine transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0015190; F:L-leucine transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0015192; F:L-phenylalanine transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0005304; F:L-valine transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0042941; P:D-alanine transport; IBA:GO_Central.
DR GO; GO:0015808; P:L-alanine transport; IBA:GO_Central.
DR GO; GO:1903806; P:L-isoleucine import across plasma membrane; IBA:GO_Central.
DR GO; GO:1903805; P:L-valine import across plasma membrane; IBA:GO_Central.
DR GO; GO:0098713; P:leucine import across plasma membrane; IBA:GO_Central.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR032823; BCA_ABC_TP_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF00005; ABC_tran; 1.
DR Pfam; PF12399; BCA_ABC_TP_C; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW Amino-acid transport; ATP-binding; Nucleotide-binding; Reference proteome;
KW Transport.
FT CHAIN 1..255
FT /note="High-affinity branched-chain amino acid transport
FT ATP-binding protein LivG"
FT /id="PRO_0000092409"
FT DOMAIN 6..254
FT /note="ABC transporter"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT BINDING 38..45
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ SEQUENCE 255 AA; 28452 MW; C9E700F3FBB49259 CRC64;
MSQPLLAVNG LMMRFGGLLA VNNVSLELRE REIVSLIGPN GAGKTTVFNC LTGFYKPTGG
TITLRERHLE GLPGQQIARM GVVRTFQHVR LFREMTVIEN LLVAQHQQLK TGLFSGLLKT
PAFRRAQSEA LDRAATWLER IGLLEHANRQ ASNLAYGDQR RLEIARCMVT QPEILMLDEP
AAGLNPKETK ELDELIAELR NHHNTTILLI EHDMKLVMGI SDRIYVVNQG TPLANGTPEE
IRNNPDVIRA YLGEA
