ID   LIVG_SHIFL              Reviewed;         255 AA.
AC   P0A9S9; P22730;
DT   19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=High-affinity branched-chain amino acid transport ATP-binding protein LivG;
DE   AltName: Full=LIV-I protein G;
GN   Name=livG; OrderedLocusNames=SF3473, S4290;
OS   Shigella flexneri.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=301 / Serotype 2a;
RX   PubMed=12384590; DOI=10.1093/nar/gkf566;
RA   Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA   Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA   Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA   Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT   "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT   through comparison with genomes of Escherichia coli K12 and O157.";
RL   Nucleic Acids Res. 30:4432-4441(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX   PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA   Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA   Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA   Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT   "Complete genome sequence and comparative genomics of Shigella flexneri
RT   serotype 2a strain 2457T.";
RL   Infect. Immun. 71:2775-2786(2003).
CC   -!- FUNCTION: Component of the leucine-specific transport system.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
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DR   EMBL; AE005674; AAN44932.1; -; Genomic_DNA.
DR   EMBL; AE014073; AAP19250.1; -; Genomic_DNA.
DR   RefSeq; NP_709225.1; NC_004337.2.
DR   RefSeq; WP_000082101.1; NZ_WPGW01000010.1.
DR   AlphaFoldDB; P0A9S9; -.
DR   SMR; P0A9S9; -.
DR   STRING; 198214.SF3473; -.
DR   EnsemblBacteria; AAN44932; AAN44932; SF3473.
DR   EnsemblBacteria; AAP19250; AAP19250; S4290.
DR   GeneID; 1026443; -.
DR   GeneID; 66672663; -.
DR   KEGG; sfl:SF3473; -.
DR   KEGG; sfx:S4290; -.
DR   PATRIC; fig|198214.7.peg.4093; -.
DR   HOGENOM; CLU_000604_1_2_6; -.
DR   OMA; EHDMRFI; -.
DR   OrthoDB; 1179151at2; -.
DR   Proteomes; UP000001006; Chromosome.
DR   Proteomes; UP000002673; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR032823; BCA_ABC_TP_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 1.
DR   Pfam; PF12399; BCA_ABC_TP_C; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE   3: Inferred from homology;
KW   Amino-acid transport; ATP-binding; Nucleotide-binding; Reference proteome;
KW   Transport.
FT   CHAIN           1..255
FT                   /note="High-affinity branched-chain amino acid transport
FT                   ATP-binding protein LivG"
FT                   /id="PRO_0000092410"
FT   DOMAIN          6..254
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         38..45
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ   SEQUENCE   255 AA;  28427 MW;  D05B2F344DF7CA85 CRC64;
     MSQPLLSVNG LMMRFGGLLA VNNVNLELYP QEIVSLIGPN GAGKTTVFNC LTGFYKPTGG
     TILLRDQHLE GLPGQQIARM GVVRTFQHVR LFREMTVIEN LLVAQHQQLK TGLFSGLLKT
     PSFRRAQSEA LDRAATWLER IGLLEHANRQ ASNLAYGDQR RLEIARCMVT QPEILMLDEP
     AAGLNPKETK ELDELIAELR NHHNTTILLI EHDMKLVMGI SDRIYVVNQG TPLANGTPEQ
     IRNNPDVIRA YLGEA