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LIVH_METJA
ID   LIVH_METJA              Reviewed;         315 AA.
AC   Q58665;
DT   26-SEP-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 108.
DE   RecName: Full=Probable branched-chain amino acid transport permease protein LivH;
GN   Name=livH; OrderedLocusNames=MJ1269;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
CC   -!- FUNCTION: Part of the binding-protein-dependent transport system for
CC       branched-chain amino acids. Probably responsible for the translocation
CC       of the substrates across the membrane (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC       permease family. LivHM subfamily. {ECO:0000305}.
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DR   EMBL; L77117; AAB99275.1; -; Genomic_DNA.
DR   PIR; D64458; D64458.
DR   AlphaFoldDB; Q58665; -.
DR   STRING; 243232.MJ_1269; -.
DR   EnsemblBacteria; AAB99275; AAB99275; MJ_1269.
DR   KEGG; mja:MJ_1269; -.
DR   eggNOG; arCOG01269; Archaea.
DR   HOGENOM; CLU_039929_1_0_2; -.
DR   InParanoid; Q58665; -.
DR   OMA; NMGWFLI; -.
DR   PhylomeDB; Q58665; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR   InterPro; IPR001851; ABC_transp_permease.
DR   Pfam; PF02653; BPD_transp_2; 1.
PE   3: Inferred from homology;
KW   Amino-acid transport; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..315
FT                   /note="Probable branched-chain amino acid transport
FT                   permease protein LivH"
FT                   /id="PRO_0000060064"
FT   TRANSMEM        14..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        49..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        70..90
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        100..120
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        150..170
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        201..221
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        224..244
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        250..270
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        283..303
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   315 AA;  33655 MW;  9AA352698413760A CRC64;
     MVKLLLKDLG EKMILEGAII YSNLLVLLAL GLTLTYITTN VPNFAQGSYA IVGSYVALTL
     LKLFGICPYL SLPVLFVVGA IVGLITYLAL KPLIKRNASV EILMIATLAI DLILLGVIGA
     YSEILSQIVG STQAKFVFAN LDFSLFGFKG ILFVSTFVVI LLLIGLYLLL YKTKFGIALR
     ASMENPSLAQ TMGIDVEKTR LFSWILSGAL AGVAGGLLPF MQEIVPATGD LIIISIFAAS
     IVGGLRHISG ALIGGYIIGI SESLITYYLA SAFGTGFLVY GKVISLIIMI ATLLIAPYGI
     TGVDWKKLKR LLSTS
 
 
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