LIVH_METJA
ID LIVH_METJA Reviewed; 315 AA.
AC Q58665;
DT 26-SEP-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 25-MAY-2022, entry version 108.
DE RecName: Full=Probable branched-chain amino acid transport permease protein LivH;
GN Name=livH; OrderedLocusNames=MJ1269;
OS Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS 10045 / NBRC 100440) (Methanococcus jannaschii).
OC Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC Methanocaldococcaceae; Methanocaldococcus.
OX NCBI_TaxID=243232;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT jannaschii.";
RL Science 273:1058-1073(1996).
CC -!- FUNCTION: Part of the binding-protein-dependent transport system for
CC branched-chain amino acids. Probably responsible for the translocation
CC of the substrates across the membrane (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. LivHM subfamily. {ECO:0000305}.
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DR EMBL; L77117; AAB99275.1; -; Genomic_DNA.
DR PIR; D64458; D64458.
DR AlphaFoldDB; Q58665; -.
DR STRING; 243232.MJ_1269; -.
DR EnsemblBacteria; AAB99275; AAB99275; MJ_1269.
DR KEGG; mja:MJ_1269; -.
DR eggNOG; arCOG01269; Archaea.
DR HOGENOM; CLU_039929_1_0_2; -.
DR InParanoid; Q58665; -.
DR OMA; NMGWFLI; -.
DR PhylomeDB; Q58665; -.
DR Proteomes; UP000000805; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR InterPro; IPR001851; ABC_transp_permease.
DR Pfam; PF02653; BPD_transp_2; 1.
PE 3: Inferred from homology;
KW Amino-acid transport; Cell membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..315
FT /note="Probable branched-chain amino acid transport
FT permease protein LivH"
FT /id="PRO_0000060064"
FT TRANSMEM 14..34
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 49..69
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 70..90
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 100..120
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 150..170
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 201..221
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 224..244
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 250..270
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 283..303
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 315 AA; 33655 MW; 9AA352698413760A CRC64;
MVKLLLKDLG EKMILEGAII YSNLLVLLAL GLTLTYITTN VPNFAQGSYA IVGSYVALTL
LKLFGICPYL SLPVLFVVGA IVGLITYLAL KPLIKRNASV EILMIATLAI DLILLGVIGA
YSEILSQIVG STQAKFVFAN LDFSLFGFKG ILFVSTFVVI LLLIGLYLLL YKTKFGIALR
ASMENPSLAQ TMGIDVEKTR LFSWILSGAL AGVAGGLLPF MQEIVPATGD LIIISIFAAS
IVGGLRHISG ALIGGYIIGI SESLITYYLA SAFGTGFLVY GKVISLIIMI ATLLIAPYGI
TGVDWKKLKR LLSTS