LIVJ_SALTY
ID LIVJ_SALTY Reviewed; 365 AA.
AC P17215;
DT 01-AUG-1990, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1990, sequence version 1.
DT 03-AUG-2022, entry version 119.
DE RecName: Full=Leu/Ile/Val/Thr-binding protein;
DE Short=LIVT-BP;
DE Flags: Precursor;
GN Name=livJ; Synonyms=livB; OrderedLocusNames=STM3567;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF 23-36.
RC STRAIN=LT2;
RX PubMed=2193932; DOI=10.1093/oxfordjournals.jbchem.a123026;
RA Ohnishi K., Nakazima A., Matsubara K., Kiritani K.;
RT "Cloning and nucleotide sequences of livB and livC, the structural genes
RT encoding binding proteins of the high-affinity branched-chain amino acid
RT transport in Salmonella typhimurium.";
RL J. Biochem. 107:202-208(1990).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
CC -!- FUNCTION: This protein is a component of the leucine, isoleucine,
CC valine, threonine transport system, which is one of the two periplasmic
CC binding protein-dependent transport systems of the high-affinity
CC transport of the branched-chain amino acids. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the leucine-binding protein family.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; D00478; BAA00369.1; -; Genomic_DNA.
DR EMBL; AE006468; AAL22427.1; -; Genomic_DNA.
DR PIR; JU0128; JU0128.
DR RefSeq; NP_462468.1; NC_003197.2.
DR RefSeq; WP_000676957.1; NC_003197.2.
DR AlphaFoldDB; P17215; -.
DR SMR; P17215; -.
DR STRING; 99287.STM3567; -.
DR PaxDb; P17215; -.
DR EnsemblBacteria; AAL22427; AAL22427; STM3567.
DR GeneID; 1255090; -.
DR KEGG; stm:STM3567; -.
DR PATRIC; fig|99287.12.peg.3770; -.
DR HOGENOM; CLU_027128_6_0_6; -.
DR OMA; MEFTGAR; -.
DR PhylomeDB; P17215; -.
DR BioCyc; SENT99287:STM3567-MON; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR InterPro; IPR028081; Leu-bd.
DR InterPro; IPR000709; Leu_Ile_Val-bd.
DR InterPro; IPR028082; Peripla_BP_I.
DR Pfam; PF13458; Peripla_BP_6; 1.
DR PRINTS; PR00337; LEUILEVALBP.
DR SUPFAM; SSF53822; SSF53822; 1.
PE 1: Evidence at protein level;
KW Amino-acid transport; Direct protein sequencing; Disulfide bond; Periplasm;
KW Reference proteome; Signal; Transport.
FT SIGNAL 1..21
FT CHAIN 22..365
FT /note="Leu/Ile/Val/Thr-binding protein"
FT /id="PRO_0000017701"
FT DISULFID 74..99
FT /evidence="ECO:0000250"
SQ SEQUENCE 365 AA; 38787 MW; 5465154B6B4D9566 CRC64;
MKGKTLLAGC IALSLSHMAF ADDIKVAVVG AMSGPVAQYG DQEFTGAEQA IADINAKGGI
KGDKLVAVKY DDACDPKQAV AVANKVVNDG IKYVIGHLCS SSTQPASDIY EDEGILMITP
AATAPELTAR GYKLVLRTTG LDSDQGPTAA KYILEKVKPQ RIAIIHDKQQ YGEGLARAVQ
DGLKKGGVNV VFFDGITAGE KDFSTLVARL KKENIDFVYY GGYHPEMGQI LRQSRAAGLK
TQFMGPEGVA NVSLSNIAGE SAEGLLVTKP KNYDQVPANK PIVDAIKAKK QDPSGAFVWT
TYAALQSLQA GLNHSDDPAE IAKYLKGATV DTVMGPLSWD EKGDLKGFEF GVFDWHANGT
ATDAK
