ID   LIVM_SALTY              Reviewed;         425 AA.
AC   P30296;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1993, sequence version 1.
DT   03-AUG-2022, entry version 117.
DE   RecName: Full=High-affinity branched-chain amino acid transport system permease protein LivM;
DE   AltName: Full=LIV-I protein M;
GN   Name=livM; Synonyms=livE; OrderedLocusNames=STM3562;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=LT2;
RX   PubMed=1429514; DOI=10.1093/oxfordjournals.jbchem.a123872;
RA   Matsubara K., Ohnishi K., Kiritani K.;
RT   "Nucleotide sequences and characterization of liv genes encoding components
RT   of the high-affinity branched-chain amino acid transport system in
RT   Salmonella typhimurium.";
RL   J. Biochem. 112:93-101(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
CC   -!- FUNCTION: Part of the binding-protein-dependent transport system for
CC       branched-chain amino acids. Probably responsible for the translocation
CC       of the substrates across the membrane.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC       permease family. LivHM subfamily. {ECO:0000305}.
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DR   EMBL; D12589; BAA02130.1; -; Genomic_DNA.
DR   EMBL; AE006468; AAL22422.1; -; Genomic_DNA.
DR   PIR; JH0669; JH0669.
DR   RefSeq; NP_462463.1; NC_003197.2.
DR   RefSeq; WP_000803766.1; NC_003197.2.
DR   AlphaFoldDB; P30296; -.
DR   STRING; 99287.STM3562; -.
DR   PaxDb; P30296; -.
DR   EnsemblBacteria; AAL22422; AAL22422; STM3562.
DR   GeneID; 1255085; -.
DR   KEGG; stm:STM3562; -.
DR   PATRIC; fig|99287.12.peg.3765; -.
DR   HOGENOM; CLU_031365_1_1_6; -.
DR   OMA; VFWYKLQ; -.
DR   PhylomeDB; P30296; -.
DR   BioCyc; SENT99287:STM3562-MON; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0015658; F:branched-chain amino acid transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0015803; P:branched-chain amino acid transport; IBA:GO_Central.
DR   CDD; cd06581; TM_PBP1_LivM_like; 1.
DR   InterPro; IPR001851; ABC_transp_permease.
DR   InterPro; IPR021807; LivHM_N.
DR   InterPro; IPR043428; LivM-like.
DR   PANTHER; PTHR30482; PTHR30482; 1.
DR   Pfam; PF02653; BPD_transp_2; 1.
DR   Pfam; PF11862; DUF3382; 1.
PE   3: Inferred from homology;
KW   Amino-acid transport; Cell inner membrane; Cell membrane; Membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..425
FT                   /note="High-affinity branched-chain amino acid transport
FT                   system permease protein LivM"
FT                   /id="PRO_0000060063"
FT   TRANSMEM        6..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        45..65
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        92..112
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        120..140
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        145..165
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        167..187
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        191..211
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        260..280
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        311..331
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        353..373
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        388..408
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   425 AA;  46408 MW;  6E7CABF9D08F690A CRC64;
     MKPMHIAMAL FSAAMFFVLA GVFMGVQLEL DGTKLVVDTA ADIRWQWIFI GTAVVFFFQL
     LRPMFQKAVK HVSGPKFILP AIDGSTVKQK LFLMALLVIA VAWPFMVSRG SVDIATMTMI
     YIILGLGLNV VVGLSGLLVL GYGGFYAIGA YTFALLNHYY GLGFWTCLPL AGLVSAAAGF
     LLGFPVLRLR GDYLAIVTLG FGEIVRILLL NNTEITGGPN GISQIPKPTL FGLEFSRSTR
     EGGWDTFSNF FGVKYDPSDR VIFLYLVALL LVVLSLFVIN RLLRMPLGRA WEALREDEIA
     CRSLGLSPTR IKLTAFTISA AFAGFAGTLF AARQGFVSPE SFTFAESAFV LAIVVLGGMG
     SQFAVILAAV LLVVSRELMR DFNEYSMLML GGLMVLMMIW RPQGLLPMTR PQLKLKSGQA
     KGEQA