LIX1L_MOUSE
ID LIX1L_MOUSE Reviewed; 337 AA.
AC Q8BQ89;
DT 18-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT 18-APR-2006, sequence version 2.
DT 25-MAY-2022, entry version 91.
DE RecName: Full=LIX1-like protein;
GN Name=Lix1l;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Spinal ganglion;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
CC -!- SIMILARITY: Belongs to the LIX1 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAC34588.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AK051276; BAC34588.1; ALT_INIT; mRNA.
DR CCDS; CCDS51004.1; -.
DR RefSeq; NP_001156642.1; NM_001163170.1.
DR AlphaFoldDB; Q8BQ89; -.
DR STRING; 10090.ENSMUSP00000057623; -.
DR PhosphoSitePlus; Q8BQ89; -.
DR MaxQB; Q8BQ89; -.
DR PaxDb; Q8BQ89; -.
DR PRIDE; Q8BQ89; -.
DR ProteomicsDB; 292100; -.
DR GeneID; 280411; -.
DR KEGG; mmu:280411; -.
DR CTD; 128077; -.
DR MGI; MGI:3036267; Lix1l.
DR eggNOG; ENOG502QR91; Eukaryota.
DR InParanoid; Q8BQ89; -.
DR OrthoDB; 1026341at2759; -.
DR PhylomeDB; Q8BQ89; -.
DR BioGRID-ORCS; 280411; 3 hits in 72 CRISPR screens.
DR ChiTaRS; Lix1l; mouse.
DR PRO; PR:Q8BQ89; -.
DR Proteomes; UP000000589; Unplaced.
DR RNAct; Q8BQ89; protein.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0097352; P:autophagosome maturation; IBA:GO_Central.
DR InterPro; IPR029270; LIX1.
DR Pfam; PF14954; LIX1; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..337
FT /note="LIX1-like protein"
FT /id="PRO_0000232873"
FT REGION 1..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 36..55
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 337 AA; 36606 MW; 2075666FCBC06396 CRC64;
METMRAQRLQ PGVGVGGRGT LRALRPGVTG APTSAATPPV GPPPAPPPPA PPLPPLLLAG
APGLPLPPGA AGSPAVLREA VEAVVRSFAK HTQGYGRVNV VEALQEFWQM KQSRGADLKN
GALVVYEMVP SNSPPYVCYV TLPGGSCFGS FQFCPTKAEA RRSAAKIALM NSVFNEHPSR
RITDEFIEKS VSEALASFNG NREEADNPNT GIGAFRFMLE SNKGKSMLEF QELMTVFQLL
HWNGSLKAMR ERQCSRQEVL AHYSHRALDD DIRHQMALDW VSREQSVPGA LSRELASTER
ELDEARLAGK ELRFHKEKKD ILMLAAGQLG NMHSSSC