ID   LIX1_CHICK              Reviewed;         281 AA.
AC   Q8UVV7;
DT   18-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Protein limb expression 1;
GN   Name=LIX1;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND DEVELOPMENTAL STAGE.
RX   PubMed=11731258; DOI=10.1016/s0925-4773(01)00535-4;
RA   Swindell E.C., Moeller C., Thaller C., Eichele G.;
RT   "Cloning and expression analysis of chicken Lix1, a founding member of a
RT   novel gene family.";
RL   Mech. Dev. 109:405-408(2001).
CC   -!- DEVELOPMENTAL STAGE: Transiently expressed in the nascent hindlimb bud
CC       between Hamburger-Hamilton stages 15 and 19. Also found in the basal
CC       plate of rhombomeres 3 and 5, in pharyngeal and in foregut mesenchyme
CC       and in all facial primordia except for the mandibular arches.
CC       {ECO:0000269|PubMed:11731258}.
CC   -!- SIMILARITY: Belongs to the LIX1 family. {ECO:0000305}.
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DR   EMBL; AF351203; AAL67189.1; -; mRNA.
DR   RefSeq; NP_989678.1; NM_204347.1.
DR   AlphaFoldDB; Q8UVV7; -.
DR   STRING; 9031.ENSGALP00000024632; -.
DR   PaxDb; Q8UVV7; -.
DR   Ensembl; ENSGALT00000024678; ENSGALP00000024632; ENSGALG00000015290.
DR   GeneID; 374264; -.
DR   KEGG; gga:374264; -.
DR   CTD; 167410; -.
DR   VEuPathDB; HostDB:geneid_374264; -.
DR   eggNOG; ENOG502QR91; Eukaryota.
DR   GeneTree; ENSGT00390000005869; -.
DR   HOGENOM; CLU_065651_1_1_1; -.
DR   InParanoid; Q8UVV7; -.
DR   OMA; AMLQEFW; -.
DR   OrthoDB; 1026341at2759; -.
DR   PhylomeDB; Q8UVV7; -.
DR   TreeFam; TF324035; -.
DR   PRO; PR:Q8UVV7; -.
DR   Proteomes; UP000000539; Chromosome Z.
DR   Bgee; ENSGALG00000015290; Expressed in granulocyte and 6 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0097352; P:autophagosome maturation; IBA:GO_Central.
DR   InterPro; IPR029270; LIX1.
DR   Pfam; PF14954; LIX1; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..281
FT                   /note="Protein limb expression 1"
FT                   /id="PRO_0000232871"
SQ   SEQUENCE   281 AA;  31952 MW;  2BCFAD9EB38B5E85 CRC64;
     MDRTLESLQL VIARVLPHRD PALVFKDLNV VAILQEFWES KQKKKAVLPS EGIIVYESLS
     SLGPPFVSYV TLPGGSCFGN FQSCLSRAEA RRDAAKVALI NSLFNELPCR RITKEFIMES
     VQEAVSSTSG NLKDADDPST SIGAYHYMLE SNIGKTMLEF QELMIVFQLL HWNGSLKALR
     ETKCSRQEVI SYYSQCSLDE KMRSHMALDW IMKEQESPGI ISQELQVALR ELEEVRKAGH
     ELRFYKEKKE ILSLALSQIY SDEVTTSSWD NQMSLALHGY R