LLPB_NOTEU
ID LLPB_NOTEU Reviewed; 174 AA.
AC Q8SQ30;
DT 27-JAN-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 25-MAY-2022, entry version 62.
DE RecName: Full=Late lactation protein B;
DE Short=LLP-B;
DE Flags: Precursor;
GN Name=LLPB;
OS Notamacropus eugenii (Tammar wallaby) (Macropus eugenii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Metatheria; Diprotodontia; Macropodidae; Notamacropus.
OX NCBI_TaxID=9315;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Mammary gland;
RX PubMed=11867236; DOI=10.1016/s0378-1119(01)00883-6;
RA Trott J.F., Wilson M.J., Hovey R.C., Shaw D.C., Nicholas K.R.;
RT "Expression of novel lipocalin-like milk protein gene is developmentally-
RT regulated during lactation in the tammar wallaby, Macropus eugenii.";
RL Gene 283:287-297(2002).
CC -!- FUNCTION: Probably serves a role in the transport of a small ligand
CC released during the hydrolysis of milk fat.
CC -!- SUBCELLULAR LOCATION: Secreted.
CC -!- TISSUE SPECIFICITY: Mammary gland specific. Secreted in milk.
CC -!- DEVELOPMENTAL STAGE: Produced during the late phase of lactation.
CC -!- SIMILARITY: Belongs to the calycin superfamily. Lipocalin family.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AF319463; AAL85634.1; -; mRNA.
DR AlphaFoldDB; Q8SQ30; -.
DR SMR; Q8SQ30; -.
DR PRIDE; Q8SQ30; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0036094; F:small molecule binding; IEA:InterPro.
DR Gene3D; 2.40.128.20; -; 1.
DR InterPro; IPR012674; Calycin.
DR InterPro; IPR002345; Lipocalin.
DR InterPro; IPR000566; Lipocln_cytosolic_FA-bd_dom.
DR InterPro; IPR002450; von_Ebner_gland.
DR PANTHER; PTHR11430; PTHR11430; 1.
DR Pfam; PF00061; Lipocalin; 1.
DR PRINTS; PR01175; VNEBNERGLAND.
DR SUPFAM; SSF50814; SSF50814; 1.
PE 2: Evidence at transcript level;
KW Disulfide bond; Milk protein; Secreted; Signal; Transport.
FT SIGNAL 1..18
FT /evidence="ECO:0000255"
FT CHAIN 19..174
FT /note="Late lactation protein B"
FT /id="PRO_0000017986"
FT DISULFID 77..169
FT /evidence="ECO:0000250"
SQ SEQUENCE 174 AA; 19875 MW; 61C48B673226EDA4 CRC64;
MKVLFLTIAL SLFSILQAQD SSSSEEQFEG TYFVKAIVTD SEFFEKNKPK ALSPLTVTHL
SNGDLEAKFT TNMNGICEEI KMKFEKTDKP GIFSTNDGSR QVLIEKTSVR DHWILFCEGE
LHGMQVRIAK LLGPHTDENP KAFQEFKKFV SLKRFNEEKI NIPRQTETCI PEHV