LLPH_CHICK
ID LLPH_CHICK Reviewed; 114 AA.
AC Q5ZHK9;
DT 06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT 23-NOV-2004, sequence version 1.
DT 03-AUG-2022, entry version 76.
DE RecName: Full=Protein LLP homolog;
DE AltName: Full=Protein LAPS18-like;
GN Name=LLPH; ORFNames=RCJMB04_37b22;
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=CB; TISSUE=Bursa of Fabricius;
RX PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA Hayashizaki Y., Buerstedde J.-M.;
RT "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT function analysis.";
RL Genome Biol. 6:R6.1-R6.9(2005).
CC -!- FUNCTION: Regulates dendritic and spine growth and synaptic
CC transmission. {ECO:0000250|UniProtKB:Q9D945}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000250|UniProtKB:Q9D945}. Chromosome
CC {ECO:0000250|UniProtKB:Q9BRT6}. Note=Cell-permeable protein (By
CC similarity). Localizes at the chromosome periphery during mitosis (By
CC similarity). {ECO:0000250|UniProtKB:Q9BRT6,
CC ECO:0000250|UniProtKB:Q9D945}.
CC -!- SIMILARITY: Belongs to the learning-associated protein family.
CC {ECO:0000305}.
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DR EMBL; AJ721125; CAG32784.1; -; mRNA.
DR RefSeq; NP_001072969.1; NM_001079501.1.
DR AlphaFoldDB; Q5ZHK9; -.
DR SMR; Q5ZHK9; -.
DR STRING; 9031.ENSGALP00000037846; -.
DR PaxDb; Q5ZHK9; -.
DR Ensembl; ENSGALT00000038638; ENSGALP00000037846; ENSGALG00000019358.
DR Ensembl; ENSGALT00000057146; ENSGALP00000054870; ENSGALG00000019358.
DR GeneID; 771027; -.
DR KEGG; gga:771027; -.
DR CTD; 84298; -.
DR VEuPathDB; HostDB:geneid_771027; -.
DR eggNOG; KOG4811; Eukaryota.
DR GeneTree; ENSGT00390000012979; -.
DR HOGENOM; CLU_134502_0_0_1; -.
DR InParanoid; Q5ZHK9; -.
DR OMA; PVWMNPR; -.
DR OrthoDB; 1594400at2759; -.
DR PhylomeDB; Q5ZHK9; -.
DR TreeFam; TF314654; -.
DR PRO; PR:Q5ZHK9; -.
DR Proteomes; UP000000539; Chromosome 1.
DR Bgee; ENSGALG00000019358; Expressed in spermatid and 14 other tissues.
DR GO; GO:0005694; C:chromosome; ISS:UniProtKB.
DR GO; GO:0005730; C:nucleolus; ISS:UniProtKB.
DR GO; GO:0001099; F:basal RNA polymerase II transcription machinery binding; ISS:UniProtKB.
DR GO; GO:0097484; P:dendrite extension; ISS:UniProtKB.
DR GO; GO:0060999; P:positive regulation of dendritic spine development; ISS:UniProtKB.
DR InterPro; IPR018784; LAPS18-like.
DR PANTHER; PTHR34253; PTHR34253; 1.
DR Pfam; PF10169; Laps; 1.
PE 3: Inferred from homology;
KW Chromosome; Nucleus; Reference proteome.
FT CHAIN 1..114
FT /note="Protein LLP homolog"
FT /id="PRO_0000274348"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 91..114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 92..108
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 114 AA; 13397 MW; 6458078E3412A9A8 CRC64;
MAKSLRSKWK RKMRAEKRKK NAPKELERLK SILRTGADVV MEEVKEVATV LPAKEALEKQ
DDCKMDVDNK RNKKTLLDQH GQYPIWMNSR QRKKLKAQRL KGKKKSKLPK GLAW
