ID   LLPH_XENLA              Reviewed;         123 AA.
AC   Q7ZY35;
DT   06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 47.
DE   RecName: Full=Protein LLP homolog;
DE   AltName: Full=Protein LAPS18-like;
GN   Name=llph;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Tail bud;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Regulates dendritic and spine growth and synaptic
CC       transmission. {ECO:0000250|UniProtKB:Q9D945}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000250|UniProtKB:Q9D945}. Chromosome
CC       {ECO:0000250|UniProtKB:Q9BRT6}. Note=Cell-permeable protein (By
CC       similarity). Localizes at the chromosome periphery during mitosis (By
CC       similarity). {ECO:0000250|UniProtKB:Q9BRT6,
CC       ECO:0000250|UniProtKB:Q9D945}.
CC   -!- SIMILARITY: Belongs to the learning-associated protein family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC043994; AAH43994.1; -; mRNA.
DR   RefSeq; NP_001079521.1; NM_001086052.1.
DR   AlphaFoldDB; Q7ZY35; -.
DR   SMR; Q7ZY35; -.
DR   MaxQB; Q7ZY35; -.
DR   DNASU; 379208; -.
DR   GeneID; 379208; -.
DR   KEGG; xla:379208; -.
DR   CTD; 379208; -.
DR   Xenbase; XB-GENE-1188271; llph.S.
DR   OrthoDB; 1594400at2759; -.
DR   Proteomes; UP000186698; Chromosome 3S.
DR   Bgee; 379208; Expressed in neurula embryo and 19 other tissues.
DR   GO; GO:0005694; C:chromosome; ISS:UniProtKB.
DR   GO; GO:0005730; C:nucleolus; ISS:UniProtKB.
DR   GO; GO:0001099; F:basal RNA polymerase II transcription machinery binding; ISS:UniProtKB.
DR   GO; GO:0097484; P:dendrite extension; ISS:UniProtKB.
DR   GO; GO:0060999; P:positive regulation of dendritic spine development; ISS:UniProtKB.
DR   InterPro; IPR018784; LAPS18-like.
DR   PANTHER; PTHR34253; PTHR34253; 1.
DR   Pfam; PF10169; Laps; 1.
PE   2: Evidence at transcript level;
KW   Chromosome; Nucleus; Reference proteome.
FT   CHAIN           1..123
FT                   /note="Protein LLP homolog"
FT                   /id="PRO_0000274350"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          61..123
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..18
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        61..87
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        104..123
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   123 AA;  14262 MW;  622446DFB246BDC7 CRC64;
     MAKSLRSKWK RKMRAEKRKK NAPKELARLK TVLAKGSNVL MDDVKEIATV VPAKKINEKM
     DLDVDAPEGE SSKMDTELKR NKKNLRDQHG QYPVWFNQRQ QKKLKSQCGK KKGKSKQAKK
     LAW