ID   LMBD2_CAEBR             Reviewed;         644 AA.
AC   Q61ZW5; A8WT65;
DT   21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 66.
DE   RecName: Full=G-protein coupled receptor-associated protein LMBRD2 {ECO:0000250|UniProtKB:Q68DH5};
GN   ORFNames=CBG02934;
OS   Caenorhabditis briggsae.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6238;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF16;
RX   PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA   Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA   Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA   Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA   Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA   Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA   Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA   Durbin R.M., Waterston R.H.;
RT   "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT   genomics.";
RL   PLoS Biol. 1:166-192(2003).
CC   -!- FUNCTION: May associate with G-protein coupled receptors and regulate
CC       downstream signaling pathways. {ECO:0000250|UniProtKB:Q68DH5}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q68DH5};
CC       Multi-pass membrane protein {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the LIMR family. {ECO:0000305}.
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DR   EMBL; HE601438; CAP23676.1; -; Genomic_DNA.
DR   RefSeq; XP_002631150.1; XM_002631104.1.
DR   AlphaFoldDB; Q61ZW5; -.
DR   SMR; Q61ZW5; -.
DR   STRING; 6238.CBG02934; -.
DR   GeneID; 8572664; -.
DR   KEGG; cbr:CBG_02934; -.
DR   CTD; 8572664; -.
DR   WormBase; CBG02934; CBP41562; WBGene00025893; -.
DR   eggNOG; KOG2296; Eukaryota.
DR   HOGENOM; CLU_018886_0_0_1; -.
DR   InParanoid; Q61ZW5; -.
DR   OMA; ERICYSA; -.
DR   OrthoDB; 778022at2759; -.
DR   Proteomes; UP000008549; Chromosome II.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006876; LMBR1-like_membr_prot.
DR   Pfam; PF04791; LMBR1; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Coiled coil; Glycoprotein; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..644
FT                   /note="G-protein coupled receptor-associated protein
FT                   LMBRD2"
FT                   /id="PRO_0000299166"
FT   TOPO_DOM        1..4
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        5..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        28..31
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        32..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        53..102
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        103..123
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        124..145
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        146..166
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        167..172
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        173..193
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        194..369
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        370..390
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        391..412
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        413..433
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        434..453
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        454..474
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        475..502
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        503..523
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        524..644
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          567..644
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          216..245
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        573..598
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        623..637
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        73
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   644 AA;  74057 MW;  905AF4BFDB72EFFC CRC64;
     MGTVSLAVQL FIVFLLTSYL LNKYSTIRKQ NPIVTISTFI GWYFSLIIVF VLPLDVAITF
     FHKCENDRQR VLNTTSTPAP IVPECELPGG YVPDDVLFDL WRVVYWSAQI LTWLILPLLQ
     SYVTAGNFTI FGKIRAAVIN NTVYYAIYSL CFLAILIYAM FKGVSINIEN LKVILVSASN
     TWGLFLLVVL LGHGLVELPR SLWHHGNRHY RLRKTYFDIE KLASEKSEAE ENVKEIYKKV
     RVLFNSMKND QNGQRRKVRT ILSKFSDDVI DQLFPSRQVI DNASMEEIGD YCSEAKLINL
     HKKTIYAVQT LNNATAQWKV LVDRALFLEN LAFSESNGYN LDLARNICVP VGVRRFWYTR
     LQTPFCRVLG VVTVFMTFFV LFSECTFFVV SYTVSPAAFV TEYASNRFHY KYTQFVAFGI
     IVYLITCAYF TIFRLQIYKY YHLDPNGHTD ENSILFSAIL LCRLTPPICL NFLGMIHMDS
     HVSMAKSFGV ETQFTKLMGH LDVIPILAKG INIYLPICII LLCAIHYYRV GAYVLHNIGF
     DQFVESDEMT NDMINSGRSL VQIERNSIKR SNERNQRNQS WTNTITSNTS TTSNAVNKYK
     RSRKNEEERP MLEEEEEMEE VSSTTRISLS PTEHPSSSGF FDDM