LMBD2_DROPS
ID LMBD2_DROPS Reviewed; 699 AA.
AC Q29BL9;
DT 21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT 04-APR-2006, sequence version 1.
DT 03-AUG-2022, entry version 56.
DE RecName: Full=LMBR1 domain-containing protein 2 homolog;
GN ORFNames=GA20843;
OS Drosophila pseudoobscura pseudoobscura (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=46245;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MV2-25 / Tucson 14011-0121.94;
RX PubMed=15632085; DOI=10.1101/gr.3059305;
RA Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S.,
RA Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P., Couronne O.,
RA Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J., van Batenburg M.F.,
RA Howells S.L., Scherer S.E., Sodergren E., Matthews B.B., Crosby M.A.,
RA Schroeder A.J., Ortiz-Barrientos D., Rives C.M., Metzker M.L., Muzny D.M.,
RA Scott G., Steffen D., Wheeler D.A., Worley K.C., Havlak P., Durbin K.J.,
RA Egan A., Gill R., Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y.,
RA Waldron L., Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.F.,
RA Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.M.,
RA Weinstock G.M., Gibbs R.A.;
RT "Comparative genome sequencing of Drosophila pseudoobscura: chromosomal,
RT gene, and cis-element evolution.";
RL Genome Res. 15:1-18(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the LIMR family. {ECO:0000305}.
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DR EMBL; CM000070; EAL26978.1; -; Genomic_DNA.
DR RefSeq; XP_001357843.1; XM_001357806.3.
DR AlphaFoldDB; Q29BL9; -.
DR SMR; Q29BL9; -.
DR STRING; 7237.FBpp0282775; -.
DR EnsemblMetazoa; FBtr0284337; FBpp0282775; FBgn0080833.
DR GeneID; 4800597; -.
DR KEGG; dpo:Dpse_GA20843; -.
DR eggNOG; KOG2296; Eukaryota.
DR HOGENOM; CLU_018886_0_0_1; -.
DR InParanoid; Q29BL9; -.
DR OMA; ERICYSA; -.
DR PhylomeDB; Q29BL9; -.
DR Proteomes; UP000001819; Chromosome 2.
DR Bgee; FBgn0080833; Expressed in female reproductive system and 2 other tissues.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR006876; LMBR1-like_membr_prot.
DR Pfam; PF04791; LMBR1; 1.
PE 3: Inferred from homology;
KW Coiled coil; Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..699
FT /note="LMBR1 domain-containing protein 2 homolog"
FT /id="PRO_0000299169"
FT TOPO_DOM 1..3
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 4..26
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 27..30
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 31..51
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 52..106
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 107..127
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 128..144
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 145..165
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 166..181
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 182..202
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 203..381
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 382..402
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 403..426
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 427..447
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 448..467
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 468..488
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 489..514
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 515..535
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 536..699
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT REGION 669..699
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 564..592
FT /evidence="ECO:0000255"
FT CARBOHYD 76
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 699 AA; 79282 MW; 128168C232F06328 CRC64;
MAYLLTFGII AALCLASISL YRYGNIPRQH ILVTLSVLTA WCFSFLIVFT IPLDVTSTLY
RQCLAEHKLA LDAAGNASTT ANITPPPECQ EPWGMVPESV FPNLWRIIYW SSQFLTWLIM
PLMQSYLKAG DFTIKGKLKS ALIENAIYYG SYLFICGVLL IYIAVKGVPL DWQKLKAIAS
SASNTWGLFL LILLLGYALV EVPRSLWNNA KPGFTLQYAY FKAAKLSTDK AEAEEHVDDI
LESLQCISRV VPNNHELRPC VETIMRKVPI ELQERASRNF SRTGGSGMGA TSSTILPSEK
ALVRIHKQVI KSLQTLQRTE ALWSVQVDTV LHLEDVARNI HSAERRFKSE FPRQRTQLER
IFYSATLQWY WECLLKAPFL KTLCVVTATM SAMVVWSEVT FFSRDPVLSI FANVIYLAKE
SYDFFTIEVF SMMVLCYFFY CTYSTILRIR FLNLYYLAPH HQTNEHSLIF SGMLLCRLTP
PMCLNFLGLI HMDSHIIPER MMETYYTRIM GHMDVIGIIS NGFNIYFPMC MLAFCLSTWF
SLGSRALNAL GFQQFLQNET IATELVQEGK DLIAREKRRR QRAEEAMARR RDFNRPDPTV
ASNDYMNKYR SGAGALAGSR TPADGLLRDG DGSFDYAAVA SSSALGVPRS LSEEINDRFG
VSTQMQVGFR GTSELDPDYE AENERRIVGP PPRGLFDDV
