ID   LMBN_STRLN              Reviewed;         275 AA.
AC   Q54367;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Lincomycin biosynthesis protein LmbN;
GN   Name=lmbN;
OS   Streptomyces lincolnensis.
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=1915;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=78-11;
RX   PubMed=8577249; DOI=10.1111/j.1365-2958.1995.tb02338.x;
RA   Peschke U., Schmidt H., Zhang H.Z., Piepersberg W.;
RT   "Molecular characterization of the lincomycin-production gene cluster of
RT   Streptomyces lincolnensis 78-11.";
RL   Mol. Microbiol. 16:1137-1156(1995).
CC   -!- PATHWAY: Antibiotic biosynthesis; lincomycin biosynthesis.
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DR   EMBL; X79146; CAA55760.1; -; Genomic_DNA.
DR   PIR; S69822; S44961.
DR   AlphaFoldDB; Q54367; -.
DR   SMR; Q54367; -.
DR   STRING; 1915.SLINC_0246; -.
DR   UniPathway; UPA00161; -.
DR   GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR   GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:1901135; P:carbohydrate derivative metabolic process; IEA:InterPro.
DR   CDD; cd05006; SIS_GmhA; 1.
DR   Gene3D; 1.10.1200.10; -; 1.
DR   InterPro; IPR036736; ACP-like_sf.
DR   InterPro; IPR035461; GmhA/DiaA.
DR   InterPro; IPR009081; PP-bd_ACP.
DR   InterPro; IPR001347; SIS_dom.
DR   InterPro; IPR046348; SIS_dom_sf.
DR   Pfam; PF13580; SIS_2; 1.
DR   SUPFAM; SSF47336; SSF47336; 1.
DR   SUPFAM; SSF53697; SSF53697; 1.
DR   PROSITE; PS50075; CARRIER; 1.
DR   PROSITE; PS51464; SIS; 1.
PE   3: Inferred from homology;
KW   Antibiotic biosynthesis; Phosphopantetheine; Phosphoprotein.
FT   CHAIN           1..275
FT                   /note="Lincomycin biosynthesis protein LmbN"
FT                   /id="PRO_0000136592"
FT   DOMAIN          1..78
FT                   /note="Carrier"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00258"
FT   DOMAIN          113..275
FT                   /note="SIS"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00797"
FT   MOD_RES         37
FT                   /note="O-(pantetheine 4'-phosphoryl)serine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00258"
SQ   SEQUENCE   275 AA;  28699 MW;  9417CE27356C0B6F CRC64;
     MSTLDEVLAL LRTIAPSGDE TELTADTLLF SSGLLDSLAL EELHVAIEER WAPIPPMELA
     RANFDTPAAI AATVARITHE ETPVSVVRNL LSDSGRLTAD LAPDAMGAGA QLLFDTWHAG
     GTTLSCGNGG SASTASHFAA DLAKLTIVPG QRRMRTLCLN DNASAFSAWT NDEGFPVVYR
     EQAEPWLEPT ATLVAFSVHG GSRGGEVSAN LPAVARLAKE RGAAVVAVTG FDGGALGDLA
     DVHINIPHAT EPVATPLIES LHVLVHHALC VAHAP