ID   LMD2A_DICDI             Reviewed;         733 AA.
AC   Q54Q92;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   03-AUG-2022, entry version 65.
DE   RecName: Full=LMBR1 domain-containing protein 2 homolog A;
GN   ORFNames=DDB_G0284019;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the LIMR family. {ECO:0000305}.
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DR   EMBL; AAFI02000059; EAL65433.1; -; Genomic_DNA.
DR   RefSeq; XP_638788.1; XM_633696.1.
DR   AlphaFoldDB; Q54Q92; -.
DR   SMR; Q54Q92; -.
DR   STRING; 44689.DDB0185797; -.
DR   PaxDb; Q54Q92; -.
DR   PRIDE; Q54Q92; -.
DR   EnsemblProtists; EAL65433; EAL65433; DDB_G0284019.
DR   GeneID; 8624377; -.
DR   KEGG; ddi:DDB_G0284019; -.
DR   dictyBase; DDB_G0284019; -.
DR   eggNOG; KOG2296; Eukaryota.
DR   HOGENOM; CLU_014778_0_0_1; -.
DR   InParanoid; Q54Q92; -.
DR   OMA; FRKEYNR; -.
DR   PhylomeDB; Q54Q92; -.
DR   PRO; PR:Q54Q92; -.
DR   Proteomes; UP000002195; Chromosome 4.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   InterPro; IPR006876; LMBR1-like_membr_prot.
DR   Pfam; PF04791; LMBR1; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..733
FT                   /note="LMBR1 domain-containing protein 2 homolog A"
FT                   /id="PRO_0000339413"
FT   TRANSMEM        1..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        33..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        125..145
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        163..183
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        191..211
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        386..406
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        423..443
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        468..488
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        513..533
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          581..641
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          649..668
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          674..696
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          232..266
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   733 AA;  83584 MW;  838DD2BFE5BDC0CA CRC64;
     MIVIFIFILI AVGLLSTKIL HRYISIKKIP WYVYISVWIG WFMCFSIVIL VPIDILCTDY
     RQCKHISDSQ SEKLNEIITN ISNGTNSGSN NNNNNNNEII NKYDSCEEPW AYISNDKLEY
     IYQTFYFGTL LLTWLVYPLM GSFVLAGDFH LSGRITRSIK ENAYLYLIFG VIGLVVMIWL
     LAVKQLDWNS MVGFAMAAAN TWGLCLVIIL MGYGLVETPR SIWVSSQRSL VLKHLQFKAV
     ELLNSKKKAN EELIATMKVI RRIQEKTKKY DPYEKYIKII VDQCPPEQYA LVQRGEGDGE
     ATYSVLVALN SRLKNAITNS QRAEFLYDQC LVEAFELQDI QNSAISLDKN VNWSFREQRQ
     GRFAKKLDIM EWIWYNYLEI SVFRVAAIVF AVLSLLIIWS EFALAFTSFD ISVLSNIVKH
     SNVSNIFVQF ILFFPLGYEA LTCYSTLFKI RIFNYYRLIP HQHSDSNSII FSAAYLCRLG
     APLCYNFIQF INMNSGIEDN RTSFSVVMGT MNVAPFLGTY FYIYFPLLIV IVCLSTLFNV
     YSRIMNCLNI SKFRFDVDFS HEQIDEGKFL IDSERRKWTQ NNIKPLSSKS PPPSLDSTSN
     NPKQIFKSGS TTISKQSPPN LNVSGGNINN NNTNNGNTSS ARSFIDSFLK KSSNNNNNNN
     NNNNPYEQTL LFDESNDFDD DDDIESGGAG RPTYNAHLSS SFNGGANSTS ISGYPQINKM
     FGGANRYSQL PKK