LNG1_ARATH
ID LNG1_ARATH Reviewed; 927 AA.
AC Q9LF24; Q0WQ78;
DT 06-FEB-2013, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 25-MAY-2022, entry version 102.
DE RecName: Full=Protein LONGIFOLIA 1;
DE AltName: Full=Protein TON1 RECRUITING MOTIF 2;
GN Name=LNG1; Synonyms=TRM2; OrderedLocusNames=At5g15580; ORFNames=T20K14.190;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 104-927.
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, AND DISRUPTION
RP PHENOTYPE.
RX PubMed=17038516; DOI=10.1242/dev.02604;
RA Lee Y.K., Kim G.T., Kim I.J., Park J., Kwak S.S., Choi G., Chung W.I.;
RT "LONGIFOLIA1 and LONGIFOLIA2, two homologous genes, regulate longitudinal
RT cell elongation in Arabidopsis.";
RL Development 133:4305-4314(2006).
RN [5]
RP INTERACTION WITH TON1A AND TON1B.
RX PubMed=22286137; DOI=10.1105/tpc.111.089748;
RA Drevensek S., Goussot M., Duroc Y., Christodoulidou A., Steyaert S.,
RA Schaefer E., Duvernois E., Grandjean O., Vantard M., Bouchez D.,
RA Pastuglia M.;
RT "The Arabidopsis TRM1-TON1 interaction reveals a recruitment network common
RT to plant cortical microtubule arrays and eukaryotic centrosomes.";
RL Plant Cell 24:178-191(2012).
CC -!- FUNCTION: In association with LNG2, regulates leaf morphology by
CC promoting longitudinal polar cell elongation independently of ROT3.
CC {ECO:0000269|PubMed:17038516}.
CC -!- SUBUNIT: Interacts (via C-terminus) with TON1A and TON1B.
CC {ECO:0000269|PubMed:22286137}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:17038516}.
CC -!- TISSUE SPECIFICITY: Expressed in roots, petioles, leaf blades and
CC floral organs. {ECO:0000269|PubMed:17038516}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype under normal growth
CC conditions, but the lng1 and lng2 double mutant shows reduced length of
CC cotyledons, rosette leaves, siliques and flowers.
CC {ECO:0000269|PubMed:17038516}.
CC -!- MISCELLANEOUS: The gain-of-function mutant lng1-1D (T-DNA tagging)
CC shows increased elongation of aerial lateral organs, partly due to
CC elongated cells in leaves, petals and siliques.
CC {ECO:0000305|PubMed:17038516}.
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DR EMBL; AL391143; CAC01757.1; -; Genomic_DNA.
DR EMBL; CP002688; AED92180.1; -; Genomic_DNA.
DR EMBL; AK228825; BAF00721.1; -; mRNA.
DR PIR; T51536; T51536.
DR RefSeq; NP_197062.1; NM_121562.3.
DR AlphaFoldDB; Q9LF24; -.
DR STRING; 3702.AT5G15580.1; -.
DR PaxDb; Q9LF24; -.
DR PRIDE; Q9LF24; -.
DR ProteomicsDB; 238440; -.
DR EnsemblPlants; AT5G15580.1; AT5G15580.1; AT5G15580.
DR GeneID; 831411; -.
DR Gramene; AT5G15580.1; AT5G15580.1; AT5G15580.
DR KEGG; ath:AT5G15580; -.
DR Araport; AT5G15580; -.
DR TAIR; locus:2180857; AT5G15580.
DR eggNOG; ENOG502R7XZ; Eukaryota.
DR HOGENOM; CLU_007647_0_0_1; -.
DR InParanoid; Q9LF24; -.
DR OMA; FKNGDHK; -.
DR OrthoDB; 185064at2759; -.
DR PhylomeDB; Q9LF24; -.
DR PRO; PR:Q9LF24; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9LF24; baseline and differential.
DR Genevisible; Q9LF24; AT.
DR GO; GO:0005829; C:cytosol; IDA:TAIR.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0051513; P:regulation of monopolar cell growth; IMP:TAIR.
DR GO; GO:0009826; P:unidimensional cell growth; IGI:TAIR.
DR InterPro; IPR025486; DUF4378.
DR InterPro; IPR033334; LNG1/2.
DR PANTHER; PTHR31680; PTHR31680; 1.
DR Pfam; PF14309; DUF4378; 1.
PE 1: Evidence at protein level;
KW Nucleus; Reference proteome.
FT CHAIN 1..927
FT /note="Protein LONGIFOLIA 1"
FT /id="PRO_0000420918"
FT REGION 41..198
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 210..257
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 460..588
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 605..626
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 61..86
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 87..130
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 150..169
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 170..193
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 210..228
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 229..257
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 480..512
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 531..556
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 563..582
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 927 AA; 104088 MW; 0BB628F06C516803 CRC64;
MSAKLLYNLS DENPNLNKQI GCMNGIFQVF YRQHYPPRRV TGDELKSLPS GKASDNVGDT
NISADKKETE KSKKKKTAKE KQRGVSSESS SRLSFSSSPC SSSFSSADIS TTASQFEQPG
LSNGENPVRE PTNGSPRWGG LMMPSDIREL VRSSIHKETR TRDEEALSQQ PKSARANVSL
LKESSPSRNS NEWSEGRRVV KLKDSPRFSY DERETRKTGA KLKETPRLSL DSRSNSFRSA
RSSCSPEPQE LVTGHRRTTS SVVAKLMGLE VIPDEPVTIQ NRENRFCDSP RPTSRVEVDL
QRSRGFDSIK KMMPAKFPMK ASPWAQVDGA KNQVKIPDAT TLTVYGEIQK RLSQLEFKKS
EKDLRALKQI LEAMEKTQQL ISKDDDDNKT LCSSNFMQRN NQPIPSAINT SSMNFKSSSI
VVMKAATAPV FKDTGIAGSA SFSPRNVALP NVKVGNLRQA QKVIPRKQSA MDVTPRPGYY
KGQTESTMKN TSTRPLQSKS DMAKSGKIQK PSVSLRTPPK KLGFEKQSRP TSPKPELNKN
QRQQLSRQQT ESASPRRKPG IKSRGLQQSE DRLSDESSDL RSLRSDSNVS LASNLDTEVT
SRYNYERNSD ITEQHTPKQR SPDLGMRSLS KPLKVTVEQP SPVSVLDVAF DEDDSPSPVR
KISIVFKEDD NLSSEESHWM NKNNNLCRSI VWPESNTSLK QPDAELTEGF MEDDAEFKNG
DHKYISEIML ASGLLRDIDY SMISIQLHQA HLPINPSLFF VLEQNKTSNV SLQDNKHKGR
GFGQQQTVNL VERSKRKLIF DTINEILAHR FAAEGCTKQP SITLSISTQR THEKSSRGEE
LLQTLCSEID RLQDNSKCIL DEDDEDLIWE DLQSHGMNWK EIEGETPGLV LDIERLIFKD
LIGEVVTSEF AAFPRMLSGQ PRQLFHC
