LNK3_ARATH
ID LNK3_ARATH Reviewed; 269 AA.
AC Q9LHH5;
DT 13-APR-2016, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 25-MAY-2022, entry version 117.
DE RecName: Full=Protein LNK3 {ECO:0000303|PubMed:23818596};
DE AltName: Full=Night light-inducible and clock-regulated 3 {ECO:0000303|PubMed:23818596};
GN Name=LNK3 {ECO:0000303|PubMed:23818596};
GN OrderedLocusNames=At3g12320 {ECO:0000312|Araport:AT3G12320};
GN ORFNames=F28J15.9 {ECO:0000312|EMBL:AAG51066.1},
GN T2E22.34 {ECO:0000312|EMBL:AAG51013.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000312|EMBL:BAB03140.1};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10907853; DOI=10.1093/dnares/7.3.217;
RA Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence
RT features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC
RT clones.";
RL DNA Res. 7:217-221(2000).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP INDUCTION, GENE FAMILY, AND NOMENCLATURE.
RX PubMed=23818596; DOI=10.1073/pnas.1302170110;
RA Rugnone M.L., Faigon Soverna A., Sanchez S.E., Schlaen R.G., Hernando C.E.,
RA Seymour D.K., Mancini E., Chernomoretz A., Weigel D., Mas P.,
RA Yanovsky M.J.;
RT "LNK genes integrate light and clock signaling networks at the core of the
RT Arabidopsis oscillator.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:12120-12125(2013).
RN [6]
RP DISRUPTION PHENOTYPE.
RX PubMed=25012192; DOI=10.1105/tpc.114.126573;
RA Xie Q., Wang P., Liu X., Yuan L., Wang L., Zhang C., Li Y., Xing H.,
RA Zhi L., Yue Z., Zhao C., McClung C.R., Xu X.;
RT "LNK1 and LNK2 are transcriptional coactivators in the Arabidopsis
RT circadian oscillator.";
RL Plant Cell 26:2843-2857(2014).
RN [7]
RP INTERACTION WITH RVE8.
RX PubMed=25848001; DOI=10.1073/pnas.1420792112;
RA Perez-Garcia P., Ma Y., Yanovsky M.J., Mas P.;
RT "Time-dependent sequestration of RVE8 by LNK proteins shapes the diurnal
RT oscillation of anthocyanin biosynthesis.";
RL Proc. Natl. Acad. Sci. U.S.A. 112:5249-5253(2015).
CC -!- FUNCTION: Probable transcriptional coactivator.
CC {ECO:0000250|UniProtKB:A8MQN2}.
CC -!- SUBUNIT: Interacts with REV8. {ECO:0000269|PubMed:25848001}.
CC -!- INDUCTION: Repressed by members of the TOC1/PRR1 family of clock genes.
CC {ECO:0000269|PubMed:23818596}.
CC -!- DISRUPTION PHENOTYPE: No effect on circadian clock.
CC {ECO:0000269|PubMed:25012192}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AP002047; BAB03140.1; -; Genomic_DNA.
DR EMBL; AC069472; AAG51066.1; -; Genomic_DNA.
DR EMBL; AC069474; AAG51013.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE75183.1; -; Genomic_DNA.
DR EMBL; CP002686; ANM64652.1; -; Genomic_DNA.
DR EMBL; AF360337; AAK28634.1; -; mRNA.
DR EMBL; AY051074; AAK93751.1; -; mRNA.
DR RefSeq; NP_001326665.1; NM_001337987.1.
DR RefSeq; NP_566419.1; NM_112067.4.
DR AlphaFoldDB; Q9LHH5; -.
DR STRING; 3702.AT3G12320.1; -.
DR iPTMnet; Q9LHH5; -.
DR PaxDb; Q9LHH5; -.
DR PRIDE; Q9LHH5; -.
DR ProteomicsDB; 238476; -.
DR EnsemblPlants; AT3G12320.1; AT3G12320.1; AT3G12320.
DR EnsemblPlants; AT3G12320.3; AT3G12320.3; AT3G12320.
DR GeneID; 820411; -.
DR Gramene; AT3G12320.1; AT3G12320.1; AT3G12320.
DR Gramene; AT3G12320.3; AT3G12320.3; AT3G12320.
DR KEGG; ath:AT3G12320; -.
DR Araport; AT3G12320; -.
DR TAIR; locus:2082264; AT3G12320.
DR eggNOG; ENOG502R7JN; Eukaryota.
DR HOGENOM; CLU_954267_0_0_1; -.
DR InParanoid; Q9LHH5; -.
DR OMA; PDSWSKW; -.
DR OrthoDB; 1619664at2759; -.
DR PhylomeDB; Q9LHH5; -.
DR PRO; PR:Q9LHH5; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9LHH5; baseline and differential.
DR GO; GO:0007623; P:circadian rhythm; IEP:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR InterPro; IPR039928; LNK.
DR PANTHER; PTHR33334; PTHR33334; 1.
PE 1: Evidence at protein level;
KW Activator; Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..269
FT /note="Protein LNK3"
FT /id="PRO_0000436033"
SQ SEQUENCE 269 AA; 30554 MW; 52F0D62365FEEE34 CRC64;
MDCYAEELVV PNYQESSSET YPSTGMWGGW SMSSPEAAEK CFDYDGFNGE GMMYSQMSMR
TSEEEEESKR SKAFYGASSL HDFEGIEQMD DMFLSSILED VPEDDGDVHR ATSSNNSVGS
SSMYGGGREV PMFHCHDMSF KEEAPFTISD LSEENMLDSN YGDELSSEEF VLQDLQRASQ
KLTDETRKCF RDTFYRLARS SQDKSDSVSP NSEELLMQTS RYDYGDGNRF SREEEIESET
NSIDRAVANL TFNKMESNIS NFPLSERVQ
