位置:首页 > 蛋白库 > LNX1_HUMAN
LNX1_HUMAN
ID   LNX1_HUMAN              Reviewed;         728 AA.
AC   Q8TBB1; Q4W5K7; Q8N4C2; Q96MJ7; Q9BY20;
DT   28-FEB-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   03-AUG-2022, entry version 183.
DE   RecName: Full=E3 ubiquitin-protein ligase LNX;
DE            EC=2.3.2.27;
DE   AltName: Full=Ligand of Numb-protein X 1;
DE   AltName: Full=Numb-binding protein 1;
DE   AltName: Full=PDZ domain-containing RING finger protein 2;
DE   AltName: Full=RING-type E3 ubiquitin transferase LNX {ECO:0000305};
GN   Name=LNX1; Synonyms=LNX, PDZRN2; ORFNames=UNQ574/PRO1136;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), AND TISSUE SPECIFICITY.
RC   TISSUE=Fetal brain;
RX   PubMed=11521506; DOI=10.1023/a:1010269908398;
RA   Xie Y., Zhao W., Wang W., Zhao S., Tang R., Ying K., Zhou Z., Mao Y.;
RT   "Identification of a human LNX protein containing multiple PDZ domains.";
RL   Biochem. Genet. 39:117-126(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RX   PubMed=12975309; DOI=10.1101/gr.1293003;
RA   Clark H.F., Gurney A.L., Abaya E., Baker K., Baldwin D.T., Brush J.,
RA   Chen J., Chow B., Chui C., Crowley C., Currell B., Deuel B., Dowd P.,
RA   Eaton D., Foster J.S., Grimaldi C., Gu Q., Hass P.E., Heldens S., Huang A.,
RA   Kim H.S., Klimowski L., Jin Y., Johnson S., Lee J., Lewis L., Liao D.,
RA   Mark M.R., Robbie E., Sanchez C., Schoenfeld J., Seshagiri S., Simmons L.,
RA   Singh J., Smith V., Stinson J., Vagts A., Vandlen R.L., Watanabe C.,
RA   Wieand D., Woods K., Xie M.-H., Yansura D.G., Yi S., Yu G., Yuan J.,
RA   Zhang M., Zhang Z., Goddard A.D., Wood W.I., Godowski P.J., Gray A.M.;
RT   "The secreted protein discovery initiative (SPDI), a large-scale effort to
RT   identify novel human secreted and transmembrane proteins: a bioinformatics
RT   assessment.";
RL   Genome Res. 13:2265-2270(2003).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC   TISSUE=Prostate;
RX   PubMed=14702039; DOI=10.1038/ng1285;
RA   Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA   Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA   Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA   Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA   Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H.,
RA   Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M.,
RA   Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K.,
RA   Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T.,
RA   Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M.,
RA   Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S.,
RA   Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H.,
RA   Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K.,
RA   Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N.,
RA   Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA   Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA   Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA   Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA   Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y.,
RA   Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K.,
RA   Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T.,
RA   Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T.,
RA   Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y.,
RA   Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H.,
RA   Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y.,
RA   Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H.,
RA   Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O.,
RA   Isogai T., Sugano S.;
RT   "Complete sequencing and characterization of 21,243 full-length human
RT   cDNAs.";
RL   Nat. Genet. 36:40-45(2004).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15815621; DOI=10.1038/nature03466;
RA   Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P.,
RA   Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C.,
RA   Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L.,
RA   Du H., Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A.,
RA   Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J.,
RA   Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M.,
RA   Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T.,
RA   Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S.,
RA   Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA   McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA   Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S.,
RA   Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C.,
RA   Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M.,
RA   Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C.,
RA   Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J.,
RA   Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E.,
RA   Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X.,
RA   Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M.,
RA   Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA   Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA   Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H.,
RA   Wilson R.K.;
RT   "Generation and annotation of the DNA sequences of human chromosomes 2 and
RT   4.";
RL   Nature 434:724-731(2005).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC   TISSUE=Brain, and Placenta;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [6]
RP   INTERACTION WITH CXADR.
RX   PubMed=12468544; DOI=10.1074/jbc.m205927200;
RA   Sollerbrant K., Raschperger E., Mirza M., Engstroem U., Philipson L.,
RA   Ljungdahl P.O., Pettersson R.F.;
RT   "The Coxsackievirus and adenovirus receptor (CAR) forms a complex with the
RT   PDZ domain-containing protein ligand-of-numb protein-X (LNX).";
RL   J. Biol. Chem. 278:7439-7444(2003).
RN   [7]
RP   INTERACTION WITH NP9.
RX   PubMed=15367597; DOI=10.1128/jvi.78.19.10310-10319.2004;
RA   Armbruester V., Sauter M., Roemer K., Best B., Hahn S., Nty A., Schmid A.,
RA   Philipp S., Mueller A., Mueller-Lantzsch N.;
RT   "Np9 protein of human endogenous retrovirus K interacts with ligand of numb
RT   protein X.";
RL   J. Virol. 78:10310-10319(2004).
RN   [8]
RP   INTERACTION WITH MAGEB18 AND MAGEF1.
RX   PubMed=20864041; DOI=10.1016/j.molcel.2010.08.029;
RA   Doyle J.M., Gao J., Wang J., Yang M., Potts P.R.;
RT   "MAGE-RING protein complexes comprise a family of E3 ubiquitin ligases.";
RL   Mol. Cell 39:963-974(2010).
RN   [9]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=21406692; DOI=10.1126/scisignal.2001570;
RA   Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T.,
RA   Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.;
RT   "System-wide temporal characterization of the proteome and phosphoproteome
RT   of human embryonic stem cell differentiation.";
RL   Sci. Signal. 4:RS3-RS3(2011).
RN   [10]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-441, AND IDENTIFICATION BY
RP   MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   TISSUE=Erythroleukemia;
RX   PubMed=23186163; DOI=10.1021/pr300630k;
RA   Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J.,
RA   Mohammed S.;
RT   "Toward a comprehensive characterization of a human cancer cell
RT   phosphoproteome.";
RL   J. Proteome Res. 12:260-271(2013).
CC   -!- FUNCTION: E3 ubiquitin-protein ligase that mediates ubiquitination and
CC       subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept
CC       ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a
CC       thioester and then directly transfers the ubiquitin to targeted
CC       substrates. Mediates ubiquitination of isoform p66 and isoform p72 of
CC       NUMB, but not that of isoform p71 or isoform p65.
CC       {ECO:0000250|UniProtKB:O70263}.
CC   -!- FUNCTION: Isoform 2 provides an endocytic scaffold for IGSF5/JAM4.
CC       {ECO:0000250|UniProtKB:O70263}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC         [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC         cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC         EC=2.3.2.27;
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC   -!- SUBUNIT: Interacts with the phosphotyrosine interaction domain of all
CC       isoforms of NUMB (By similarity). Interacts with MAGEB18 and MAGEF1.
CC       Interacts with the Coxsackievirus and adenovirus receptor CXADR.
CC       Interacts with endogenous retrovirus K protein Np9. IGSF5/JAM4
CC       interacts with isoform 2 through the second PDZ domain, other isoforms
CC       may also interact with IGSF5/JAM4 (By similarity). {ECO:0000250}.
CC   -!- INTERACTION:
CC       Q8TBB1; P01023: A2M; NbExp=3; IntAct=EBI-739832, EBI-640741;
CC       Q8TBB1; Q9NYB9-2: ABI2; NbExp=3; IntAct=EBI-739832, EBI-11096309;
CC       Q8TBB1; Q9BWD1: ACAT2; NbExp=3; IntAct=EBI-739832, EBI-1047273;
CC       Q8TBB1; P12814: ACTN1; NbExp=3; IntAct=EBI-739832, EBI-351710;
CC       Q8TBB1; Q08043: ACTN3; NbExp=3; IntAct=EBI-739832, EBI-2880652;
CC       Q8TBB1; O43707: ACTN4; NbExp=3; IntAct=EBI-739832, EBI-351526;
CC       Q8TBB1; Q96HD9: ACY3; NbExp=3; IntAct=EBI-739832, EBI-3916242;
CC       Q8TBB1; Q6UY14-3: ADAMTSL4; NbExp=3; IntAct=EBI-739832, EBI-10173507;
CC       Q8TBB1; Q6RW13: AGTRAP; NbExp=3; IntAct=EBI-739832, EBI-741181;
CC       Q8TBB1; Q6RW13-2: AGTRAP; NbExp=3; IntAct=EBI-739832, EBI-11522760;
CC       Q8TBB1; Q96BJ3: AIDA; NbExp=3; IntAct=EBI-739832, EBI-4401674;
CC       Q8TBB1; Q13155: AIMP2; NbExp=8; IntAct=EBI-739832, EBI-745226;
CC       Q8TBB1; P09972: ALDOC; NbExp=6; IntAct=EBI-739832, EBI-2952751;
CC       Q8TBB1; Q96Q83: ALKBH3; NbExp=3; IntAct=EBI-739832, EBI-6658697;
CC       Q8TBB1; Q49AR9: ANKS1A; NbExp=3; IntAct=EBI-739832, EBI-11954519;
CC       Q8TBB1; Q9BXS5: AP1M1; NbExp=3; IntAct=EBI-739832, EBI-541426;
CC       Q8TBB1; Q96GX9: APIP; NbExp=11; IntAct=EBI-739832, EBI-359248;
CC       Q8TBB1; Q9BRG6: APOL4; NbExp=3; IntAct=EBI-739832, EBI-10296818;
CC       Q8TBB1; P61204: ARF3; NbExp=3; IntAct=EBI-739832, EBI-641535;
CC       Q8TBB1; P53365: ARFIP2; NbExp=3; IntAct=EBI-739832, EBI-638194;
CC       Q8TBB1; Q8N5M1: ATPAF2; NbExp=11; IntAct=EBI-739832, EBI-1166928;
CC       Q8TBB1; Q8WXE1: ATRIP; NbExp=3; IntAct=EBI-739832, EBI-747353;
CC       Q8TBB1; P54253: ATXN1; NbExp=6; IntAct=EBI-739832, EBI-930964;
CC       Q8TBB1; Q9Y2T1: AXIN2; NbExp=3; IntAct=EBI-739832, EBI-4400025;
CC       Q8TBB1; Q8N7W2-2: BEND7; NbExp=3; IntAct=EBI-739832, EBI-10181188;
CC       Q8TBB1; Q8TD16-2: BICD2; NbExp=3; IntAct=EBI-739832, EBI-11975051;
CC       Q8TBB1; Q13490: BIRC2; NbExp=3; IntAct=EBI-739832, EBI-514538;
CC       Q8TBB1; P53004: BLVRA; NbExp=5; IntAct=EBI-739832, EBI-7410441;
CC       Q8TBB1; Q9H2G9: BLZF1; NbExp=3; IntAct=EBI-739832, EBI-2548012;
CC       Q8TBB1; Q96GS4: BORCS6; NbExp=3; IntAct=EBI-739832, EBI-10193358;
CC       Q8TBB1; Q9H0C5: BTBD1; NbExp=3; IntAct=EBI-739832, EBI-935503;
CC       Q8TBB1; Q9BXJ1: C1QTNF1; NbExp=3; IntAct=EBI-739832, EBI-750200;
CC       Q8TBB1; Q9BXJ1-2: C1QTNF1; NbExp=3; IntAct=EBI-739832, EBI-11536642;
CC       Q8TBB1; P35219: CA8; NbExp=6; IntAct=EBI-739832, EBI-718700;
CC       Q8TBB1; Q9NP86: CABP5; NbExp=3; IntAct=EBI-739832, EBI-10311131;
CC       Q8TBB1; A2RRN7: CADPS; NbExp=3; IntAct=EBI-739832, EBI-10179719;
CC       Q8TBB1; Q9H257-2: CARD9; NbExp=3; IntAct=EBI-739832, EBI-11530605;
CC       Q8TBB1; P55212: CASP6; NbExp=3; IntAct=EBI-739832, EBI-718729;
CC       Q8TBB1; Q86XM0: CATSPERD; NbExp=3; IntAct=EBI-739832, EBI-10260328;
CC       Q8TBB1; P83916: CBX1; NbExp=3; IntAct=EBI-739832, EBI-78129;
CC       Q8TBB1; Q9Y3M2: CBY1; NbExp=3; IntAct=EBI-739832, EBI-947308;
CC       Q8TBB1; Q8NA61-2: CBY2; NbExp=7; IntAct=EBI-739832, EBI-11524851;
CC       Q8TBB1; Q6UXH8-3: CCBE1; NbExp=3; IntAct=EBI-739832, EBI-12013534;
CC       Q8TBB1; Q68D86: CCDC102B; NbExp=4; IntAct=EBI-739832, EBI-10171570;
CC       Q8TBB1; A6NC98: CCDC88B; NbExp=3; IntAct=EBI-739832, EBI-347573;
CC       Q8TBB1; Q7Z6B0-2: CCDC91; NbExp=3; IntAct=EBI-739832, EBI-12012082;
CC       Q8TBB1; O95273: CCNDBP1; NbExp=3; IntAct=EBI-739832, EBI-748961;
CC       Q8TBB1; P32320: CDA; NbExp=9; IntAct=EBI-739832, EBI-9250559;
CC       Q8TBB1; O14735: CDIPT; NbExp=3; IntAct=EBI-739832, EBI-358858;
CC       Q8TBB1; P55273: CDKN2D; NbExp=3; IntAct=EBI-739832, EBI-745859;
CC       Q8TBB1; Q8NHQ1: CEP70; NbExp=3; IntAct=EBI-739832, EBI-739624;
CC       Q8TBB1; Q9P209: CEP72; NbExp=6; IntAct=EBI-739832, EBI-739498;
CC       Q8TBB1; Q8TAP6: CEP76; NbExp=3; IntAct=EBI-739832, EBI-742887;
CC       Q8TBB1; Q6P2H3-3: CEP85; NbExp=3; IntAct=EBI-739832, EBI-12368239;
CC       Q8TBB1; Q96Q77: CIB3; NbExp=3; IntAct=EBI-739832, EBI-10292696;
CC       Q8TBB1; Q14011: CIRBP; NbExp=3; IntAct=EBI-739832, EBI-538850;
CC       Q8TBB1; P49759-3: CLK1; NbExp=3; IntAct=EBI-739832, EBI-11981867;
CC       Q8TBB1; P49760: CLK2; NbExp=8; IntAct=EBI-739832, EBI-750020;
CC       Q8TBB1; P49761: CLK3; NbExp=3; IntAct=EBI-739832, EBI-745579;
CC       Q8TBB1; Q96DZ9-2: CMTM5; NbExp=3; IntAct=EBI-739832, EBI-11522780;
CC       Q8TBB1; P38432: COIL; NbExp=2; IntAct=EBI-739832, EBI-945751;
CC       Q8TBB1; Q96FN4: CPNE2; NbExp=3; IntAct=EBI-739832, EBI-7097057;
CC       Q8TBB1; Q8N684-3: CPSF7; NbExp=3; IntAct=EBI-739832, EBI-11523759;
CC       Q8TBB1; Q8N4Y2-3: CRACR2B; NbExp=3; IntAct=EBI-739832, EBI-11982645;
CC       Q8TBB1; O43186: CRX; NbExp=3; IntAct=EBI-739832, EBI-748171;
CC       Q8TBB1; Q9NS75: CYSLTR2; NbExp=3; IntAct=EBI-739832, EBI-3843579;
CC       Q8TBB1; A8MQ03: CYSRT1; NbExp=3; IntAct=EBI-739832, EBI-3867333;
CC       Q8TBB1; O75553: DAB1; NbExp=5; IntAct=EBI-739832, EBI-7875264;
CC       Q8TBB1; Q9H773: DCTPP1; NbExp=3; IntAct=EBI-739832, EBI-723569;
CC       Q8TBB1; Q9BTE7: DCUN1D5; NbExp=3; IntAct=EBI-739832, EBI-3924013;
CC       Q8TBB1; P35638: DDIT3; NbExp=3; IntAct=EBI-739832, EBI-742651;
CC       Q8TBB1; Q92841: DDX17; NbExp=4; IntAct=EBI-739832, EBI-746012;
CC       Q8TBB1; Q6P3S1-5: DENND1B; NbExp=3; IntAct=EBI-739832, EBI-12105346;
CC       Q8TBB1; Q9BUN8: DERL1; NbExp=3; IntAct=EBI-739832, EBI-398977;
CC       Q8TBB1; Q05D60: DEUP1; NbExp=3; IntAct=EBI-739832, EBI-748597;
CC       Q8TBB1; P49366: DHPS; NbExp=3; IntAct=EBI-739832, EBI-741925;
CC       Q8TBB1; Q14565: DMC1; NbExp=3; IntAct=EBI-739832, EBI-930865;
CC       Q8TBB1; G5E9A7: DMWD; NbExp=3; IntAct=EBI-739832, EBI-10976677;
CC       Q8TBB1; Q9ULA0: DNPEP; NbExp=7; IntAct=EBI-739832, EBI-748356;
CC       Q8TBB1; Q92785: DPF2; NbExp=3; IntAct=EBI-739832, EBI-359932;
CC       Q8TBB1; Q14919: DRAP1; NbExp=3; IntAct=EBI-739832, EBI-712941;
CC       Q8TBB1; Q9Y295: DRG1; NbExp=3; IntAct=EBI-739832, EBI-719554;
CC       Q8TBB1; Q86UW9: DTX2; NbExp=3; IntAct=EBI-739832, EBI-740376;
CC       Q8TBB1; Q68J44: DUSP29; NbExp=5; IntAct=EBI-739832, EBI-1054321;
CC       Q8TBB1; Q8WWB3: DYDC1; NbExp=3; IntAct=EBI-739832, EBI-740680;
CC       Q8TBB1; P63172: DYNLT1; NbExp=3; IntAct=EBI-739832, EBI-1176455;
CC       Q8TBB1; Q96F86: EDC3; NbExp=3; IntAct=EBI-739832, EBI-997311;
CC       Q8TBB1; Q96G04: EEF2KMT; NbExp=3; IntAct=EBI-739832, EBI-747840;
CC       Q8TBB1; O95967: EFEMP2; NbExp=3; IntAct=EBI-739832, EBI-743414;
CC       Q8TBB1; Q5JST6: EFHC2; NbExp=3; IntAct=EBI-739832, EBI-2349927;
CC       Q8TBB1; Q9H6Z9: EGLN3; NbExp=3; IntAct=EBI-739832, EBI-1175354;
CC       Q8TBB1; Q8N9N8: EIF1AD; NbExp=3; IntAct=EBI-739832, EBI-750700;
CC       Q8TBB1; P38919: EIF4A3; NbExp=3; IntAct=EBI-739832, EBI-299104;
CC       Q8TBB1; Q15056: EIF4H; NbExp=4; IntAct=EBI-739832, EBI-748492;
CC       Q8TBB1; Q8TC92: ENOX1; NbExp=4; IntAct=EBI-739832, EBI-713221;
CC       Q8TBB1; Q7L775: EPM2AIP1; NbExp=3; IntAct=EBI-739832, EBI-6255981;
CC       Q8TBB1; Q96CN4: EVI5L; NbExp=3; IntAct=EBI-739832, EBI-749523;
CC       Q8TBB1; Q9Y3B2: EXOSC1; NbExp=3; IntAct=EBI-739832, EBI-371892;
CC       Q8TBB1; Q9NPD3: EXOSC4; NbExp=3; IntAct=EBI-739832, EBI-371823;
CC       Q8TBB1; Q96B26: EXOSC8; NbExp=6; IntAct=EBI-739832, EBI-371922;
CC       Q8TBB1; Q9NWS6: FAM118A; NbExp=4; IntAct=EBI-739832, EBI-8638992;
CC       Q8TBB1; Q86V42: FAM124A; NbExp=3; IntAct=EBI-739832, EBI-744506;
CC       Q8TBB1; Q86YD7: FAM90A1; NbExp=3; IntAct=EBI-739832, EBI-6658203;
CC       Q8TBB1; Q8IZU0: FAM9B; NbExp=3; IntAct=EBI-739832, EBI-10175124;
CC       Q8TBB1; P49327: FASN; NbExp=3; IntAct=EBI-739832, EBI-356658;
CC       Q8TBB1; Q9NXK8: FBXL12; NbExp=3; IntAct=EBI-739832, EBI-719790;
CC       Q8TBB1; O15409: FOXP2; NbExp=3; IntAct=EBI-739832, EBI-983612;
CC       Q8TBB1; A1L4K1: FSD2; NbExp=3; IntAct=EBI-739832, EBI-5661036;
CC       Q8TBB1; P51114-2: FXR1; NbExp=3; IntAct=EBI-739832, EBI-11022345;
CC       Q8TBB1; P31150: GDI1; NbExp=6; IntAct=EBI-739832, EBI-946999;
CC       Q8TBB1; P14136: GFAP; NbExp=3; IntAct=EBI-739832, EBI-744302;
CC       Q8TBB1; O76003: GLRX3; NbExp=3; IntAct=EBI-739832, EBI-374781;
CC       Q8TBB1; Q96IK5: GMCL1; NbExp=3; IntAct=EBI-739832, EBI-2548508;
CC       Q8TBB1; O75496: GMNN; NbExp=3; IntAct=EBI-739832, EBI-371669;
CC       Q8TBB1; Q9H4A5: GOLPH3L; NbExp=3; IntAct=EBI-739832, EBI-4403434;
CC       Q8TBB1; Q92917: GPKOW; NbExp=5; IntAct=EBI-739832, EBI-746309;
CC       Q8TBB1; O75791: GRAP2; NbExp=4; IntAct=EBI-739832, EBI-740418;
CC       Q8TBB1; P62993: GRB2; NbExp=4; IntAct=EBI-739832, EBI-401755;
CC       Q8TBB1; Q4V328: GRIPAP1; NbExp=3; IntAct=EBI-739832, EBI-717919;
CC       Q8TBB1; Q96NT3-2: GUCD1; NbExp=3; IntAct=EBI-739832, EBI-11978177;
CC       Q8TBB1; Q7Z353: HDX; NbExp=3; IntAct=EBI-739832, EBI-1052734;
CC       Q8TBB1; V9HW56: HEL-S-108; NbExp=3; IntAct=EBI-739832, EBI-10330141;
CC       Q8TBB1; V9HWB8: HEL-S-30; NbExp=3; IntAct=EBI-739832, EBI-10215395;
CC       Q8TBB1; V9HWF5: HEL-S-69p; NbExp=3; IntAct=EBI-739832, EBI-10330249;
CC       Q8TBB1; V9HW80: HEL-S-70; NbExp=3; IntAct=EBI-739832, EBI-10175326;
CC       Q8TBB1; P07686: HEXB; NbExp=3; IntAct=EBI-739832, EBI-7133736;
CC       Q8TBB1; Q96MH2: HEXIM2; NbExp=5; IntAct=EBI-739832, EBI-5460660;
CC       Q8TBB1; O00291: HIP1; NbExp=3; IntAct=EBI-739832, EBI-473886;
CC       Q8TBB1; Q6NT76: HMBOX1; NbExp=3; IntAct=EBI-739832, EBI-2549423;
CC       Q8TBB1; Q9NP66: HMG20A; NbExp=3; IntAct=EBI-739832, EBI-740641;
CC       Q8TBB1; P52597: HNRNPF; NbExp=3; IntAct=EBI-739832, EBI-352986;
CC       Q8TBB1; P31943: HNRNPH1; NbExp=3; IntAct=EBI-739832, EBI-351590;
CC       Q8TBB1; Q9NSC5: HOMER3; NbExp=6; IntAct=EBI-739832, EBI-748420;
CC       Q8TBB1; Q8IX15-3: HOMEZ; NbExp=3; IntAct=EBI-739832, EBI-10172004;
CC       Q8TBB1; Q96ED9-2: HOOK2; NbExp=3; IntAct=EBI-739832, EBI-10961706;
CC       Q8TBB1; P49639: HOXA1; NbExp=3; IntAct=EBI-739832, EBI-740785;
CC       Q8TBB1; O75506: HSBP1; NbExp=10; IntAct=EBI-739832, EBI-748664;
CC       Q8TBB1; O75031: HSF2BP; NbExp=3; IntAct=EBI-739832, EBI-7116203;
CC       Q8TBB1; P42858: HTT; NbExp=6; IntAct=EBI-739832, EBI-466029;
CC       Q8TBB1; Q8IYA8: IHO1; NbExp=3; IntAct=EBI-739832, EBI-8638439;
CC       Q8TBB1; Q9UKT9: IKZF3; NbExp=3; IntAct=EBI-739832, EBI-747204;
CC       Q8TBB1; Q14005-2: IL16; NbExp=3; IntAct=EBI-739832, EBI-17178971;
CC       Q8TBB1; Q8NBZ0: INO80E; NbExp=3; IntAct=EBI-739832, EBI-769401;
CC       Q8TBB1; Q9BT40: INPP5K; NbExp=3; IntAct=EBI-739832, EBI-749162;
CC       Q8TBB1; Q96PC2: IP6K3; NbExp=3; IntAct=EBI-739832, EBI-10990676;
CC       Q8TBB1; Q9H1K1: ISCU; NbExp=3; IntAct=EBI-739832, EBI-1047335;
CC       Q8TBB1; Q8WXH2: JPH3; NbExp=3; IntAct=EBI-739832, EBI-1055254;
CC       Q8TBB1; Q8IYT4: KATNAL2; NbExp=3; IntAct=EBI-739832, EBI-1044332;
CC       Q8TBB1; Q719H9: KCTD1; NbExp=7; IntAct=EBI-739832, EBI-9027502;
CC       Q8TBB1; Q8WZ19: KCTD13; NbExp=5; IntAct=EBI-739832, EBI-742916;
CC       Q8TBB1; Q8NC69: KCTD6; NbExp=4; IntAct=EBI-739832, EBI-2511344;
CC       Q8TBB1; Q96MP8-2: KCTD7; NbExp=3; IntAct=EBI-739832, EBI-11954971;
CC       Q8TBB1; Q7L273: KCTD9; NbExp=6; IntAct=EBI-739832, EBI-4397613;
CC       Q8TBB1; Q5VWX1: KHDRBS2; NbExp=3; IntAct=EBI-739832, EBI-742808;
CC       Q8TBB1; Q86T90: KIAA1328; NbExp=3; IntAct=EBI-739832, EBI-3437878;
CC       Q8TBB1; Q5T7B8-2: KIF24; NbExp=3; IntAct=EBI-739832, EBI-10213781;
CC       Q8TBB1; Q9BVG8-5: KIFC3; NbExp=3; IntAct=EBI-739832, EBI-14069005;
CC       Q8TBB1; Q53G59: KLHL12; NbExp=4; IntAct=EBI-739832, EBI-740929;
CC       Q8TBB1; Q5T749: KPRP; NbExp=3; IntAct=EBI-739832, EBI-10981970;
CC       Q8TBB1; P19012: KRT15; NbExp=5; IntAct=EBI-739832, EBI-739566;
CC       Q8TBB1; P08779: KRT16; NbExp=3; IntAct=EBI-739832, EBI-356410;
CC       Q8TBB1; Q07627: KRTAP1-1; NbExp=3; IntAct=EBI-739832, EBI-11959885;
CC       Q8TBB1; P60410: KRTAP10-8; NbExp=3; IntAct=EBI-739832, EBI-10171774;
CC       Q8TBB1; P60328: KRTAP12-3; NbExp=3; IntAct=EBI-739832, EBI-11953334;
CC       Q8TBB1; Q3SY46: KRTAP13-3; NbExp=3; IntAct=EBI-739832, EBI-10241252;
CC       Q8TBB1; Q9BYR9: KRTAP2-4; NbExp=3; IntAct=EBI-739832, EBI-14065470;
CC       Q8TBB1; Q9BYR5: KRTAP4-2; NbExp=7; IntAct=EBI-739832, EBI-10172511;
CC       Q8TBB1; P26371: KRTAP5-9; NbExp=3; IntAct=EBI-739832, EBI-3958099;
CC       Q8TBB1; Q9BYQ4: KRTAP9-2; NbExp=3; IntAct=EBI-739832, EBI-1044640;
CC       Q8TBB1; Q9BYQ3: KRTAP9-3; NbExp=3; IntAct=EBI-739832, EBI-1043191;
CC       Q8TBB1; Q9BYQ0: KRTAP9-8; NbExp=3; IntAct=EBI-739832, EBI-11958364;
CC       Q8TBB1; Q9BQD3: KXD1; NbExp=4; IntAct=EBI-739832, EBI-739657;
CC       Q8TBB1; Q6UWP7: LCLAT1; NbExp=3; IntAct=EBI-739832, EBI-10254507;
CC       Q8TBB1; Q13094: LCP2; NbExp=3; IntAct=EBI-739832, EBI-346946;
CC       Q8TBB1; O43679: LDB2; NbExp=3; IntAct=EBI-739832, EBI-2865580;
CC       Q8TBB1; O95214: LEPROTL1; NbExp=3; IntAct=EBI-739832, EBI-750776;
CC       Q8TBB1; Q8TCE9: LGALS14; NbExp=3; IntAct=EBI-739832, EBI-10274069;
CC       Q8TBB1; P50458: LHX2; NbExp=3; IntAct=EBI-739832, EBI-12179869;
CC       Q8TBB1; Q17RB8: LONRF1; NbExp=3; IntAct=EBI-739832, EBI-2341787;
CC       Q8TBB1; Q5JTD7: LRRC73; NbExp=3; IntAct=EBI-739832, EBI-12003882;
CC       Q8TBB1; Q9Y333: LSM2; NbExp=3; IntAct=EBI-739832, EBI-347416;
CC       Q8TBB1; Q9P127: LUZP4; NbExp=3; IntAct=EBI-739832, EBI-10198848;
CC       Q8TBB1; Q9Y250: LZTS1; NbExp=3; IntAct=EBI-739832, EBI-1216080;
CC       Q8TBB1; Q9Y6D9: MAD1L1; NbExp=3; IntAct=EBI-739832, EBI-742610;
CC       Q8TBB1; Q96M61: MAGEB18; NbExp=13; IntAct=EBI-739832, EBI-741835;
CC       Q8TBB1; P45984: MAPK9; NbExp=7; IntAct=EBI-739832, EBI-713568;
CC       Q8TBB1; Q15555: MAPRE2; NbExp=3; IntAct=EBI-739832, EBI-739717;
CC       Q8TBB1; Q9Y316: MEMO1; NbExp=6; IntAct=EBI-739832, EBI-1104564;
CC       Q8TBB1; Q6FHY5: MEOX2; NbExp=3; IntAct=EBI-739832, EBI-16439278;
CC       Q8TBB1; Q8WXB1: METTL21A; NbExp=4; IntAct=EBI-739832, EBI-8652459;
CC       Q8TBB1; Q9UJV3-2: MID2; NbExp=6; IntAct=EBI-739832, EBI-10172526;
CC       Q8TBB1; Q9UH92-3: MLX; NbExp=3; IntAct=EBI-739832, EBI-8852072;
CC       Q8TBB1; Q96HT8: MRFAP1L1; NbExp=7; IntAct=EBI-739832, EBI-748896;
CC       Q8TBB1; P82932: MRPS6; NbExp=3; IntAct=EBI-739832, EBI-716172;
CC       Q8TBB1; Q8NCY6: MSANTD4; NbExp=3; IntAct=EBI-739832, EBI-7850168;
CC       Q8TBB1; O60682: MSC; NbExp=3; IntAct=EBI-739832, EBI-740310;
CC       Q8TBB1; Q96QG7: MTMR9; NbExp=5; IntAct=EBI-739832, EBI-744593;
CC       Q8TBB1; Q5JR59: MTUS2; NbExp=4; IntAct=EBI-739832, EBI-742948;
CC       Q8TBB1; Q5JR59-3: MTUS2; NbExp=3; IntAct=EBI-739832, EBI-11522433;
CC       Q8TBB1; Q9H7P6: MVB12B; NbExp=3; IntAct=EBI-739832, EBI-6149062;
CC       Q8TBB1; Q9P2K5-2: MYEF2; NbExp=3; IntAct=EBI-739832, EBI-10318831;
CC       Q8TBB1; Q15742: NAB2; NbExp=3; IntAct=EBI-739832, EBI-8641936;
CC       Q8TBB1; O95544: NADK; NbExp=5; IntAct=EBI-739832, EBI-743949;
CC       Q8TBB1; Q9UJ70: NAGK; NbExp=3; IntAct=EBI-739832, EBI-372578;
CC       Q8TBB1; Q9UJ70-2: NAGK; NbExp=3; IntAct=EBI-739832, EBI-11526455;
CC       Q8TBB1; O43639: NCK2; NbExp=3; IntAct=EBI-739832, EBI-713635;
CC       Q8TBB1; O14777: NDC80; NbExp=3; IntAct=EBI-739832, EBI-715849;
CC       Q8TBB1; Q9UHB4: NDOR1; NbExp=3; IntAct=EBI-739832, EBI-10249760;
CC       Q8TBB1; O14561: NDUFAB1; NbExp=3; IntAct=EBI-739832, EBI-1246261;
CC       Q8TBB1; P19404: NDUFV2; NbExp=3; IntAct=EBI-739832, EBI-713665;
CC       Q8TBB1; Q8N987: NECAB1; NbExp=3; IntAct=EBI-739832, EBI-11956853;
CC       Q8TBB1; Q7Z6G3-2: NECAB2; NbExp=6; IntAct=EBI-739832, EBI-10172876;
CC       Q8TBB1; Q9HC98: NEK6; NbExp=3; IntAct=EBI-739832, EBI-740364;
CC       Q8TBB1; P35240: NF2; NbExp=3; IntAct=EBI-739832, EBI-1014472;
CC       Q8TBB1; P15531: NME1; NbExp=3; IntAct=EBI-739832, EBI-741141;
CC       Q8TBB1; Q9Y5B8: NME7; NbExp=9; IntAct=EBI-739832, EBI-744782;
CC       Q8TBB1; Q7Z3S9: NOTCH2NLA; NbExp=4; IntAct=EBI-739832, EBI-945833;
CC       Q8TBB1; P0DPK4: NOTCH2NLC; NbExp=3; IntAct=EBI-739832, EBI-22310682;
CC       Q8TBB1; O95848: NUDT14; NbExp=8; IntAct=EBI-739832, EBI-536866;
CC       Q8TBB1; P37198: NUP62; NbExp=3; IntAct=EBI-739832, EBI-347978;
CC       Q8TBB1; Q9NPJ8: NXT2; NbExp=3; IntAct=EBI-739832, EBI-752122;
CC       Q8TBB1; Q96M63: ODAD1; NbExp=3; IntAct=EBI-739832, EBI-10173858;
CC       Q8TBB1; Q9P0S3: ORMDL1; NbExp=3; IntAct=EBI-739832, EBI-1054848;
CC       Q8TBB1; Q969R2: OSBP2; NbExp=3; IntAct=EBI-739832, EBI-7405817;
CC       Q8TBB1; Q969R2-2: OSBP2; NbExp=3; IntAct=EBI-739832, EBI-12211505;
CC       Q8TBB1; Q9H4L5: OSBPL3; NbExp=3; IntAct=EBI-739832, EBI-1051317;
CC       Q8TBB1; Q9UJX0: OSGIN1; NbExp=6; IntAct=EBI-739832, EBI-9057006;
CC       Q8TBB1; Q9H8K7: PAAT; NbExp=5; IntAct=EBI-739832, EBI-714785;
CC       Q8TBB1; Q15102: PAFAH1B3; NbExp=9; IntAct=EBI-739832, EBI-711522;
CC       Q8TBB1; P22234: PAICS; NbExp=4; IntAct=EBI-739832, EBI-712261;
CC       Q8TBB1; Q9P286: PAK5; NbExp=3; IntAct=EBI-739832, EBI-741896;
CC       Q8TBB1; P30039: PBLD; NbExp=3; IntAct=EBI-739832, EBI-750589;
CC       Q8TBB1; P61457: PCBD1; NbExp=7; IntAct=EBI-739832, EBI-740475;
CC       Q8TBB1; Q13370: PDE3B; NbExp=3; IntAct=EBI-739832, EBI-6172856;
CC       Q8TBB1; Q99471: PFDN5; NbExp=3; IntAct=EBI-739832, EBI-357275;
CC       Q8TBB1; Q9HB19: PLEKHA2; NbExp=5; IntAct=EBI-739832, EBI-4401947;
CC       Q8TBB1; Q8ND90: PNMA1; NbExp=7; IntAct=EBI-739832, EBI-302345;
CC       Q8TBB1; Q9UL41: PNMA3; NbExp=3; IntAct=EBI-739832, EBI-11278955;
CC       Q8TBB1; Q96PV4: PNMA5; NbExp=3; IntAct=EBI-739832, EBI-10171633;
CC       Q8TBB1; P11086: PNMT; NbExp=3; IntAct=EBI-739832, EBI-11305767;
CC       Q8TBB1; Q8WZA1: POMGNT1; NbExp=4; IntAct=EBI-739832, EBI-3912424;
CC       Q8TBB1; P78424: POU6F2; NbExp=3; IntAct=EBI-739832, EBI-12029004;
CC       Q8TBB1; P62937: PPIA; NbExp=3; IntAct=EBI-739832, EBI-437708;
CC       Q8TBB1; O43447: PPIH; NbExp=3; IntAct=EBI-739832, EBI-1055615;
CC       Q8TBB1; Q96KQ4: PPP1R13B; NbExp=3; IntAct=EBI-739832, EBI-1105153;
CC       Q8TBB1; Q9GZV8: PRDM14; NbExp=5; IntAct=EBI-739832, EBI-3957793;
CC       Q8TBB1; P31321: PRKAR1B; NbExp=3; IntAct=EBI-739832, EBI-2805516;
CC       Q8TBB1; O60260-5: PRKN; NbExp=3; IntAct=EBI-739832, EBI-21251460;
CC       Q8TBB1; O75569: PRKRA; NbExp=3; IntAct=EBI-739832, EBI-713955;
CC       Q8TBB1; O14744: PRMT5; NbExp=3; IntAct=EBI-739832, EBI-351098;
CC       Q8TBB1; P41219: PRPH; NbExp=6; IntAct=EBI-739832, EBI-752074;
CC       Q8TBB1; Q9NZ81: PRR13; NbExp=4; IntAct=EBI-739832, EBI-740924;
CC       Q8TBB1; Q9NRG1: PRTFDC1; NbExp=3; IntAct=EBI-739832, EBI-739759;
CC       Q8TBB1; P62191: PSMC1; NbExp=3; IntAct=EBI-739832, EBI-357598;
CC       Q8TBB1; Q9UL46: PSME2; NbExp=3; IntAct=EBI-739832, EBI-741630;
CC       Q8TBB1; P61289: PSME3; NbExp=3; IntAct=EBI-739832, EBI-355546;
CC       Q8TBB1; Q92530: PSMF1; NbExp=3; IntAct=EBI-739832, EBI-945916;
CC       Q8TBB1; Q03393: PTS; NbExp=3; IntAct=EBI-739832, EBI-712344;
CC       Q8TBB1; Q96QR8: PURB; NbExp=3; IntAct=EBI-739832, EBI-2880222;
CC       Q8TBB1; P47897: QARS1; NbExp=3; IntAct=EBI-739832, EBI-347462;
CC       Q8TBB1; Q14088: RAB33A; NbExp=3; IntAct=EBI-739832, EBI-744685;
CC       Q8TBB1; P47224: RABIF; NbExp=3; IntAct=EBI-739832, EBI-713992;
CC       Q8TBB1; O75771: RAD51D; NbExp=6; IntAct=EBI-739832, EBI-1055693;
CC       Q8TBB1; Q9Y620: RAD54B; NbExp=4; IntAct=EBI-739832, EBI-740830;
CC       Q8TBB1; Q53GL6: RALY; NbExp=3; IntAct=EBI-739832, EBI-9512693;
CC       Q8TBB1; Q9NYW8: RBAK; NbExp=3; IntAct=EBI-739832, EBI-1210429;
CC       Q8TBB1; Q9BYM8: RBCK1; NbExp=3; IntAct=EBI-739832, EBI-2340624;
CC       Q8TBB1; Q5T481: RBM20; NbExp=3; IntAct=EBI-739832, EBI-11352885;
CC       Q8TBB1; P38159: RBMX; NbExp=4; IntAct=EBI-739832, EBI-743526;
CC       Q8TBB1; P0DJD3: RBMY1A1; NbExp=4; IntAct=EBI-739832, EBI-8638511;
CC       Q8TBB1; Q15415: RBMY1J; NbExp=3; IntAct=EBI-739832, EBI-8642021;
CC       Q8TBB1; Q96HR9-2: REEP6; NbExp=3; IntAct=EBI-739832, EBI-14065960;
CC       Q8TBB1; O75679: RFPL3; NbExp=3; IntAct=EBI-739832, EBI-10188956;
CC       Q8TBB1; O76081-6: RGS20; NbExp=3; IntAct=EBI-739832, EBI-10178530;
CC       Q8TBB1; Q8IUF8: RIOX2; NbExp=3; IntAct=EBI-739832, EBI-751580;
CC       Q8TBB1; Q9Y3C5: RNF11; NbExp=3; IntAct=EBI-739832, EBI-396669;
CC       Q8TBB1; Q96HH0: ROBO3; NbExp=3; IntAct=EBI-739832, EBI-10288358;
CC       Q8TBB1; Q9HAT0: ROPN1; NbExp=5; IntAct=EBI-739832, EBI-1378139;
CC       Q8TBB1; P49247: RPIA; NbExp=5; IntAct=EBI-739832, EBI-744831;
CC       Q8TBB1; Q6ZNE9: RUFY4; NbExp=6; IntAct=EBI-739832, EBI-10181525;
CC       Q8TBB1; Q59EK9-3: RUNDC3A; NbExp=3; IntAct=EBI-739832, EBI-11957366;
CC       Q8TBB1; Q9Y230: RUVBL2; NbExp=6; IntAct=EBI-739832, EBI-352939;
CC       Q8TBB1; P33764: S100A3; NbExp=3; IntAct=EBI-739832, EBI-1044747;
CC       Q8TBB1; P04271: S100B; NbExp=3; IntAct=EBI-739832, EBI-458391;
CC       Q8TBB1; P21673: SAT1; NbExp=8; IntAct=EBI-739832, EBI-711613;
CC       Q8TBB1; Q9UN30-2: SCML1; NbExp=3; IntAct=EBI-739832, EBI-12137487;
CC       Q8TBB1; Q9UQR0: SCML2; NbExp=3; IntAct=EBI-739832, EBI-2513111;
CC       Q8TBB1; Q9BWG6: SCNM1; NbExp=3; IntAct=EBI-739832, EBI-748391;
CC       Q8TBB1; Q8WYJ6: SEPTIN1; NbExp=3; IntAct=EBI-739832, EBI-693002;
CC       Q8TBB1; Q96ES7: SGF29; NbExp=3; IntAct=EBI-739832, EBI-743117;
CC       Q8TBB1; Q9NUL5-4: SHFL; NbExp=3; IntAct=EBI-739832, EBI-11955083;
CC       Q8TBB1; P37840: SNCA; NbExp=3; IntAct=EBI-739832, EBI-985879;
CC       Q8TBB1; Q9BV90: SNRNP25; NbExp=3; IntAct=EBI-739832, EBI-9675976;
CC       Q8TBB1; P09012: SNRPA; NbExp=3; IntAct=EBI-739832, EBI-607085;
CC       Q8TBB1; P62306: SNRPF; NbExp=3; IntAct=EBI-739832, EBI-356900;
CC       Q8TBB1; Q02446: SP4; NbExp=3; IntAct=EBI-739832, EBI-10198587;
CC       Q8TBB1; Q9NZD8: SPG21; NbExp=3; IntAct=EBI-739832, EBI-742688;
CC       Q8TBB1; Q7Z699: SPRED1; NbExp=3; IntAct=EBI-739832, EBI-5235340;
CC       Q8TBB1; P12931: SRC; NbExp=6; IntAct=EBI-739832, EBI-621482;
CC       Q8TBB1; P84103: SRSF3; NbExp=3; IntAct=EBI-739832, EBI-372557;
CC       Q8TBB1; O43805: SSNA1; NbExp=7; IntAct=EBI-739832, EBI-2515299;
CC       Q8TBB1; Q6ZMT1: STAC2; NbExp=3; IntAct=EBI-739832, EBI-948802;
CC       Q8TBB1; Q9HCH5-13: SYTL2; NbExp=3; IntAct=EBI-739832, EBI-14291493;
CC       Q8TBB1; Q9BSH4: TACO1; NbExp=3; IntAct=EBI-739832, EBI-747797;
CC       Q8TBB1; Q13148: TARDBP; NbExp=3; IntAct=EBI-739832, EBI-372899;
CC       Q8TBB1; Q86VP1: TAX1BP1; NbExp=3; IntAct=EBI-739832, EBI-529518;
CC       Q8TBB1; Q86TI0: TBC1D1; NbExp=3; IntAct=EBI-739832, EBI-1644036;
CC       Q8TBB1; Q5QJ74: TBCEL; NbExp=3; IntAct=EBI-739832, EBI-10244795;
CC       Q8TBB1; Q99081-3: TCF12; NbExp=3; IntAct=EBI-739832, EBI-11952764;
CC       Q8TBB1; P56279: TCL1A; NbExp=3; IntAct=EBI-739832, EBI-749995;
CC       Q8TBB1; P48775: TDO2; NbExp=3; IntAct=EBI-739832, EBI-743494;
CC       Q8TBB1; Q8WW24: TEKT4; NbExp=3; IntAct=EBI-739832, EBI-750487;
CC       Q8TBB1; Q96PF1: TGM7; NbExp=3; IntAct=EBI-739832, EBI-12029034;
CC       Q8TBB1; Q9NVV9: THAP1; NbExp=3; IntAct=EBI-739832, EBI-741515;
CC       Q8TBB1; Q9BT49: THAP7; NbExp=3; IntAct=EBI-739832, EBI-741350;
CC       Q8TBB1; Q9NWX6: THG1L; NbExp=3; IntAct=EBI-739832, EBI-746510;
CC       Q8TBB1; Q8WW34-2: TMEM239; NbExp=3; IntAct=EBI-739832, EBI-11528917;
CC       Q8TBB1; Q13829: TNFAIP1; NbExp=3; IntAct=EBI-739832, EBI-2505861;
CC       Q8TBB1; P21580: TNFAIP3; NbExp=3; IntAct=EBI-739832, EBI-527670;
CC       Q8TBB1; Q13077: TRAF1; NbExp=7; IntAct=EBI-739832, EBI-359224;
CC       Q8TBB1; Q12933: TRAF2; NbExp=5; IntAct=EBI-739832, EBI-355744;
CC       Q8TBB1; Q13114: TRAF3; NbExp=3; IntAct=EBI-739832, EBI-357631;
CC       Q8TBB1; Q9BUZ4: TRAF4; NbExp=3; IntAct=EBI-739832, EBI-3650647;
CC       Q8TBB1; O00463: TRAF5; NbExp=3; IntAct=EBI-739832, EBI-523498;
CC       Q8TBB1; Q9Y4K3: TRAF6; NbExp=3; IntAct=EBI-739832, EBI-359276;
CC       Q8TBB1; Q9UDY6-2: TRIM10; NbExp=3; IntAct=EBI-739832, EBI-11981577;
CC       Q8TBB1; Q14142: TRIM14; NbExp=3; IntAct=EBI-739832, EBI-2820256;
CC       Q8TBB1; P19474: TRIM21; NbExp=3; IntAct=EBI-739832, EBI-81290;
CC       Q8TBB1; P36406: TRIM23; NbExp=3; IntAct=EBI-739832, EBI-740098;
CC       Q8TBB1; P14373: TRIM27; NbExp=3; IntAct=EBI-739832, EBI-719493;
CC       Q8TBB1; O75382: TRIM3; NbExp=3; IntAct=EBI-739832, EBI-2129889;
CC       Q8TBB1; Q9HCM9: TRIM39; NbExp=3; IntAct=EBI-739832, EBI-739510;
CC       Q8TBB1; Q9HCM9-2: TRIM39; NbExp=3; IntAct=EBI-739832, EBI-11523450;
CC       Q8TBB1; Q8IWZ5: TRIM42; NbExp=3; IntAct=EBI-739832, EBI-5235829;
CC       Q8TBB1; Q86XT4: TRIM50; NbExp=5; IntAct=EBI-739832, EBI-9867283;
CC       Q8TBB1; Q9BYV2: TRIM54; NbExp=7; IntAct=EBI-739832, EBI-2130429;
CC       Q8TBB1; Q495X7: TRIM60; NbExp=3; IntAct=EBI-739832, EBI-13576620;
CC       Q8TBB1; Q6AZZ1: TRIM68; NbExp=3; IntAct=EBI-739832, EBI-2130449;
CC       Q8TBB1; Q9BZR9: TRIM8; NbExp=5; IntAct=EBI-739832, EBI-2340370;
CC       Q8TBB1; Q15645: TRIP13; NbExp=8; IntAct=EBI-739832, EBI-358993;
CC       Q8TBB1; Q15654: TRIP6; NbExp=3; IntAct=EBI-739832, EBI-742327;
CC       Q8TBB1; Q53H54: TRMT12; NbExp=3; IntAct=EBI-739832, EBI-10242598;
CC       Q8TBB1; Q86WV8: TSC1; NbExp=3; IntAct=EBI-739832, EBI-12806590;
CC       Q8TBB1; Q99816: TSG101; NbExp=3; IntAct=EBI-739832, EBI-346882;
CC       Q8TBB1; Q15631: TSN; NbExp=3; IntAct=EBI-739832, EBI-1044160;
CC       Q8TBB1; Q9H2G4: TSPYL2; NbExp=3; IntAct=EBI-739832, EBI-947459;
CC       Q8TBB1; Q96PN8: TSSK3; NbExp=7; IntAct=EBI-739832, EBI-3918381;
CC       Q8TBB1; P57075-2: UBASH3A; NbExp=3; IntAct=EBI-739832, EBI-7353612;
CC       Q8TBB1; Q9Y2X8: UBE2D4; NbExp=5; IntAct=EBI-739832, EBI-745527;
CC       Q8TBB1; Q9NZI7: UBP1; NbExp=3; IntAct=EBI-739832, EBI-2795133;
CC       Q8TBB1; O95045-2: UPP2; NbExp=3; IntAct=EBI-739832, EBI-11528386;
CC       Q8TBB1; Q70EL1-9: USP54; NbExp=3; IntAct=EBI-739832, EBI-11975223;
CC       Q8TBB1; Q6EMK4: VASN; NbExp=3; IntAct=EBI-739832, EBI-10249550;
CC       Q8TBB1; P55072: VCP; NbExp=4; IntAct=EBI-739832, EBI-355164;
CC       Q8TBB1; Q2NL98: VMAC; NbExp=3; IntAct=EBI-739832, EBI-2803134;
CC       Q8TBB1; Q9H9H4: VPS37B; NbExp=3; IntAct=EBI-739832, EBI-4400866;
CC       Q8TBB1; Q8N1B4: VPS52; NbExp=3; IntAct=EBI-739832, EBI-2799833;
CC       Q8TBB1; Q64LD2-2: WDR25; NbExp=3; IntAct=EBI-739832, EBI-12032042;
CC       Q8TBB1; P63104: YWHAZ; NbExp=3; IntAct=EBI-739832, EBI-347088;
CC       Q8TBB1; O96006: ZBED1; NbExp=3; IntAct=EBI-739832, EBI-740037;
CC       Q8TBB1; Q8N680: ZBTB2; NbExp=3; IntAct=EBI-739832, EBI-2515601;
CC       Q8TBB1; O43167: ZBTB24; NbExp=6; IntAct=EBI-739832, EBI-744471;
CC       Q8TBB1; Q9HCK0: ZBTB26; NbExp=3; IntAct=EBI-739832, EBI-3918996;
CC       Q8TBB1; O43298: ZBTB43; NbExp=5; IntAct=EBI-739832, EBI-740718;
CC       Q8TBB1; Q8TBK6: ZCCHC10; NbExp=3; IntAct=EBI-739832, EBI-597063;
CC       Q8TBB1; Q9NTW7: ZFP64; NbExp=4; IntAct=EBI-739832, EBI-711679;
CC       Q8TBB1; Q8N5A5-2: ZGPAT; NbExp=3; IntAct=EBI-739832, EBI-10183064;
CC       Q8TBB1; Q9UQR1-2: ZNF148; NbExp=3; IntAct=EBI-739832, EBI-11742222;
CC       Q8TBB1; O14771: ZNF213; NbExp=3; IntAct=EBI-739832, EBI-12838388;
CC       Q8TBB1; O14978: ZNF263; NbExp=3; IntAct=EBI-739832, EBI-744493;
CC       Q8TBB1; Q9UL40: ZNF346; NbExp=3; IntAct=EBI-739832, EBI-2462313;
CC       Q8TBB1; Q9BUY5: ZNF426; NbExp=3; IntAct=EBI-739832, EBI-743265;
CC       Q8TBB1; Q9NWS9-2: ZNF446; NbExp=3; IntAct=EBI-739832, EBI-740232;
CC       Q8TBB1; Q9H707: ZNF552; NbExp=3; IntAct=EBI-739832, EBI-2555731;
CC       Q8TBB1; Q9P0T4: ZNF581; NbExp=6; IntAct=EBI-739832, EBI-745520;
CC       Q8TBB1; O00488: ZNF593; NbExp=3; IntAct=EBI-739832, EBI-726769;
CC       Q8TBB1; Q8N720: ZNF655; NbExp=5; IntAct=EBI-739832, EBI-625509;
CC       Q8TBB1; Q9UGI0: ZRANB1; NbExp=3; IntAct=EBI-739832, EBI-527853;
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=Q8TBB1-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q8TBB1-2; Sequence=VSP_005733;
CC   -!- TISSUE SPECIFICITY: Expressed in heart, placenta, kidney, pancreas and
CC       brain. {ECO:0000269|PubMed:11521506}.
CC   -!- DOMAIN: The NPXY motif is required for the interaction with the PID
CC       domain of NUMB. It is however not sufficient.
CC   -!- DOMAIN: The PDZ 1 domain participates in the interaction with the PID
CC       domain of NUMB, and participates in the isoform-specific ubiquitination
CC       of NUMB. The PDZ 2 domain of isoform 2 participates in the interaction
CC       with IGSF5/JAM4, other isoforms containing this domain may also
CC       interact with IGSF5/JAM4 (By similarity). {ECO:0000250}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AF237782; AAK15039.1; -; mRNA.
DR   EMBL; AY358326; AAQ88692.1; -; mRNA.
DR   EMBL; AK056823; BAB71291.1; -; mRNA.
DR   EMBL; AC058822; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC095040; AAY41000.1; -; Genomic_DNA.
DR   EMBL; BC022983; AAH22983.1; -; mRNA.
DR   EMBL; BC034737; AAH34737.1; -; mRNA.
DR   CCDS; CCDS3492.1; -. [Q8TBB1-2]
DR   CCDS; CCDS47057.1; -. [Q8TBB1-1]
DR   RefSeq; NP_001119800.1; NM_001126328.2. [Q8TBB1-1]
DR   RefSeq; NP_116011.2; NM_032622.2. [Q8TBB1-2]
DR   RefSeq; XP_005265842.1; XM_005265785.4. [Q8TBB1-1]
DR   RefSeq; XP_016864265.1; XM_017008776.1. [Q8TBB1-1]
DR   PDB; 3B76; X-ray; 1.75 A; A/B=504-594.
DR   PDB; 5H7R; X-ray; 1.70 A; D=11-138.
DR   PDB; 5H7S; X-ray; 3.49 A; B/D=11-138.
DR   PDBsum; 3B76; -.
DR   PDBsum; 5H7R; -.
DR   PDBsum; 5H7S; -.
DR   AlphaFoldDB; Q8TBB1; -.
DR   SMR; Q8TBB1; -.
DR   BioGRID; 124219; 567.
DR   ELM; Q8TBB1; -.
DR   IntAct; Q8TBB1; 418.
DR   MINT; Q8TBB1; -.
DR   STRING; 9606.ENSP00000263925; -.
DR   MoonDB; Q8TBB1; Predicted.
DR   iPTMnet; Q8TBB1; -.
DR   PhosphoSitePlus; Q8TBB1; -.
DR   BioMuta; LNX1; -.
DR   DMDM; 29840786; -.
DR   jPOST; Q8TBB1; -.
DR   MassIVE; Q8TBB1; -.
DR   PaxDb; Q8TBB1; -.
DR   PeptideAtlas; Q8TBB1; -.
DR   PRIDE; Q8TBB1; -.
DR   ProteomicsDB; 73982; -. [Q8TBB1-1]
DR   ProteomicsDB; 73983; -. [Q8TBB1-2]
DR   Antibodypedia; 1114; 237 antibodies from 29 providers.
DR   DNASU; 84708; -.
DR   Ensembl; ENST00000263925.8; ENSP00000263925.7; ENSG00000072201.14. [Q8TBB1-1]
DR   Ensembl; ENST00000306888.6; ENSP00000302879.2; ENSG00000072201.14. [Q8TBB1-2]
DR   GeneID; 84708; -.
DR   KEGG; hsa:84708; -.
DR   MANE-Select; ENST00000263925.8; ENSP00000263925.7; NM_001126328.3; NP_001119800.1.
DR   UCSC; uc003haf.5; human. [Q8TBB1-1]
DR   CTD; 84708; -.
DR   DisGeNET; 84708; -.
DR   GeneCards; LNX1; -.
DR   HGNC; HGNC:6657; LNX1.
DR   HPA; ENSG00000072201; Low tissue specificity.
DR   MIM; 609732; gene.
DR   neXtProt; NX_Q8TBB1; -.
DR   OpenTargets; ENSG00000072201; -.
DR   PharmGKB; PA30419; -.
DR   VEuPathDB; HostDB:ENSG00000072201; -.
DR   eggNOG; KOG0297; Eukaryota.
DR   eggNOG; KOG3528; Eukaryota.
DR   GeneTree; ENSGT00940000158757; -.
DR   HOGENOM; CLU_021213_0_0_1; -.
DR   InParanoid; Q8TBB1; -.
DR   OMA; AYGPRDD; -.
DR   OrthoDB; 615205at2759; -.
DR   PhylomeDB; Q8TBB1; -.
DR   TreeFam; TF330709; -.
DR   PathwayCommons; Q8TBB1; -.
DR   Reactome; R-HSA-983168; Antigen processing: Ubiquitination & Proteasome degradation.
DR   SignaLink; Q8TBB1; -.
DR   SIGNOR; Q8TBB1; -.
DR   UniPathway; UPA00143; -.
DR   BioGRID-ORCS; 84708; 10 hits in 1116 CRISPR screens.
DR   ChiTaRS; LNX1; human.
DR   EvolutionaryTrace; Q8TBB1; -.
DR   GeneWiki; LNX1; -.
DR   GenomeRNAi; 84708; -.
DR   Pharos; Q8TBB1; Tbio.
DR   PRO; PR:Q8TBB1; -.
DR   Proteomes; UP000005640; Chromosome 4.
DR   RNAct; Q8TBB1; protein.
DR   Bgee; ENSG00000072201; Expressed in esophagus squamous epithelium and 184 other tissues.
DR   ExpressionAtlas; Q8TBB1; baseline and differential.
DR   Genevisible; Q8TBB1; HS.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030165; F:PDZ domain binding; IEA:Ensembl.
DR   GO; GO:0004842; F:ubiquitin-protein transferase activity; IBA:GO_Central.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR   Gene3D; 2.30.42.10; -; 4.
DR   Gene3D; 3.30.40.10; -; 1.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR036034; PDZ_sf.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR017907; Znf_RING_CS.
DR   Pfam; PF00595; PDZ; 4.
DR   SMART; SM00228; PDZ; 4.
DR   SMART; SM00184; RING; 1.
DR   SUPFAM; SSF50156; SSF50156; 4.
DR   PROSITE; PS50106; PDZ; 4.
DR   PROSITE; PS00518; ZF_RING_1; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Alternative splicing; Cytoplasm; Metal-binding;
KW   Phosphoprotein; Reference proteome; Repeat; Transferase;
KW   Ubl conjugation pathway; Zinc; Zinc-finger.
FT   CHAIN           1..728
FT                   /note="E3 ubiquitin-protein ligase LNX"
FT                   /id="PRO_0000055913"
FT   DOMAIN          274..359
FT                   /note="PDZ 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00143"
FT   DOMAIN          381..464
FT                   /note="PDZ 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00143"
FT   DOMAIN          507..593
FT                   /note="PDZ 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00143"
FT   DOMAIN          638..724
FT                   /note="PDZ 4"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00143"
FT   ZN_FING         41..79
FT                   /note="RING-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00175"
FT   REGION          178..214
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          186..244
FT                   /note="Interaction with MAGEB18"
FT                   /evidence="ECO:0000269|PubMed:20864041"
FT   REGION          475..494
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           181..184
FT                   /note="NPXY motif"
FT   COMPBIAS        475..489
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         441
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:23186163"
FT   VAR_SEQ         1..127
FT                   /note="MNQPESANDPEPLCAVCGQAHSLEENHFYSYPEEVDDDLICHICLQALLDPL
FT                   DTPCGHTYCTLCLTNFLVEKDFCPMDRKPLVLQHCKKSSILVNKLLNKLLVTCPFREHC
FT                   TQVLQRCDLEHHFQTS -> MKALLLLVLPWLSPANYIDNVGNLHFLYSEL (in
FT                   isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:11521506,
FT                   ECO:0000303|PubMed:12975309, ECO:0000303|PubMed:15489334"
FT                   /id="VSP_005733"
FT   CONFLICT        132
FT                   /note="S -> F (in Ref. 1; AAK15039)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        321
FT                   /note="G -> R (in Ref. 3; BAB71291)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        366
FT                   /note="N -> T (in Ref. 3; BAB71291)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        411
FT                   /note="V -> A (in Ref. 3; BAB71291)"
FT                   /evidence="ECO:0000305"
FT   TURN            15..17
FT                   /evidence="ECO:0007829|PDB:5H7R"
FT   HELIX           37..39
FT                   /evidence="ECO:0007829|PDB:5H7R"
FT   TURN            42..44
FT                   /evidence="ECO:0007829|PDB:5H7R"
FT   STRAND          45..47
FT                   /evidence="ECO:0007829|PDB:5H7R"
FT   STRAND          49..53
FT                   /evidence="ECO:0007829|PDB:5H7R"
FT   STRAND          59..61
FT                   /evidence="ECO:0007829|PDB:5H7R"
FT   HELIX           62..71
FT                   /evidence="ECO:0007829|PDB:5H7R"
FT   TURN            76..78
FT                   /evidence="ECO:0007829|PDB:5H7R"
FT   HELIX           84..86
FT                   /evidence="ECO:0007829|PDB:5H7R"
FT   HELIX           92..99
FT                   /evidence="ECO:0007829|PDB:5H7R"
FT   STRAND          102..104
FT                   /evidence="ECO:0007829|PDB:5H7R"
FT   TURN            108..110
FT                   /evidence="ECO:0007829|PDB:5H7R"
FT   STRAND          114..116
FT                   /evidence="ECO:0007829|PDB:5H7R"
FT   HELIX           117..119
FT                   /evidence="ECO:0007829|PDB:5H7R"
FT   HELIX           120..126
FT                   /evidence="ECO:0007829|PDB:5H7R"
FT   HELIX           129..133
FT                   /evidence="ECO:0007829|PDB:5H7R"
FT   STRAND          504..511
FT                   /evidence="ECO:0007829|PDB:3B76"
FT   STRAND          520..524
FT                   /evidence="ECO:0007829|PDB:3B76"
FT   STRAND          535..540
FT                   /evidence="ECO:0007829|PDB:3B76"
FT   HELIX           545..549
FT                   /evidence="ECO:0007829|PDB:3B76"
FT   STRAND          557..561
FT                   /evidence="ECO:0007829|PDB:3B76"
FT   HELIX           566..568
FT                   /evidence="ECO:0007829|PDB:3B76"
FT   HELIX           571..579
FT                   /evidence="ECO:0007829|PDB:3B76"
FT   STRAND          583..594
FT                   /evidence="ECO:0007829|PDB:3B76"
SQ   SEQUENCE   728 AA;  80629 MW;  5590E8D8976AE093 CRC64;
     MNQPESANDP EPLCAVCGQA HSLEENHFYS YPEEVDDDLI CHICLQALLD PLDTPCGHTY
     CTLCLTNFLV EKDFCPMDRK PLVLQHCKKS SILVNKLLNK LLVTCPFREH CTQVLQRCDL
     EHHFQTSCKG ASHYGLTKDR KRRSQDGCPD GCASLTATAP SPEVSAAATI SLMTDEPGLD
     NPAYVSSAED GQPAISPVDS GRSNRTRARP FERSTIRSRS FKKINRALSV LRRTKSGSAV
     ANHADQGREN SENTTAPEVF PRLYHLIPDG EITSIKINRV DPSESLSIRL VGGSETPLVH
     IIIQHIYRDG VIARDGRLLP GDIILKVNGM DISNVPHNYA VRLLRQPCQV LWLTVMREQK
     FRSRNNGQAP DAYRPRDDSF HVILNKSSPE EQLGIKLVRK VDEPGVFIFN VLDGGVAYRH
     GQLEENDRVL AINGHDLRYG SPESAAHLIQ ASERRVHLVV SRQVRQRSPD IFQEAGWNSN
     GSWSPGPGER SNTPKPLHPT ITCHEKVVNI QKDPGESLGM TVAGGASHRE WDLPIYVISV
     EPGGVISRDG RIKTGDILLN VDGVELTEVS RSEAVALLKR TSSSIVLKAL EVKEYEPQED
     CSSPAALDSN HNMAPPSDWS PSWVMWLELP RCLYNCKDIV LRRNTAGSLG FCIVGGYEEY
     NGNKPFFIKS IVEGTPAYND GRIRCGDILL AVNGRSTSGM IHACLARLLK ELKGRITLTI
     VSWPGTFL
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024