LOC1_ASPNC
ID LOC1_ASPNC Reviewed; 189 AA.
AC A2R4J9;
DT 23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 06-MAR-2007, sequence version 1.
DT 25-MAY-2022, entry version 54.
DE RecName: Full=60S ribosomal subunit assembly/export protein loc1;
GN Name=loc1; ORFNames=An15g00680;
OS Aspergillus niger (strain CBS 513.88 / FGSC A1513).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=425011;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 513.88 / FGSC A1513 / ATCC MYA-4892;
RX PubMed=17259976; DOI=10.1038/nbt1282;
RA Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G., Schaap P.J.,
RA Turner G., de Vries R.P., Albang R., Albermann K., Andersen M.R.,
RA Bendtsen J.D., Benen J.A.E., van den Berg M., Breestraat S., Caddick M.X.,
RA Contreras R., Cornell M., Coutinho P.M., Danchin E.G.J., Debets A.J.M.,
RA Dekker P., van Dijck P.W.M., van Dijk A., Dijkhuizen L., Driessen A.J.M.,
RA d'Enfert C., Geysens S., Goosen C., Groot G.S.P., de Groot P.W.J.,
RA Guillemette T., Henrissat B., Herweijer M., van den Hombergh J.P.T.W.,
RA van den Hondel C.A.M.J.J., van der Heijden R.T.J.M., van der Kaaij R.M.,
RA Klis F.M., Kools H.J., Kubicek C.P., van Kuyk P.A., Lauber J., Lu X.,
RA van der Maarel M.J.E.C., Meulenberg R., Menke H., Mortimer M.A.,
RA Nielsen J., Oliver S.G., Olsthoorn M., Pal K., van Peij N.N.M.E.,
RA Ram A.F.J., Rinas U., Roubos J.A., Sagt C.M.J., Schmoll M., Sun J.,
RA Ussery D., Varga J., Vervecken W., van de Vondervoort P.J.J., Wedler H.,
RA Woesten H.A.B., Zeng A.-P., van Ooyen A.J.J., Visser J., Stam H.;
RT "Genome sequencing and analysis of the versatile cell factory Aspergillus
RT niger CBS 513.88.";
RL Nat. Biotechnol. 25:221-231(2007).
CC -!- FUNCTION: Required for efficient assembly and nuclear export of the 60S
CC ribosomal subunit. {ECO:0000250}.
CC -!- SUBUNIT: Component of the 66S pre-ribosomal particle. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the LOC1 family. {ECO:0000305}.
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DR EMBL; AM270331; CAK42237.1; -; Genomic_DNA.
DR RefSeq; XP_001396607.1; XM_001396570.1.
DR AlphaFoldDB; A2R4J9; -.
DR SMR; A2R4J9; -.
DR PaxDb; A2R4J9; -.
DR EnsemblFungi; CAK42237; CAK42237; An15g00680.
DR GeneID; 4987667; -.
DR KEGG; ang:ANI_1_130134; -.
DR VEuPathDB; FungiDB:An15g00680; -.
DR HOGENOM; CLU_096593_0_0_1; -.
DR Proteomes; UP000006706; Chromosome 3R.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0003729; F:mRNA binding; IEA:InterPro.
DR GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR GO; GO:0042273; P:ribosomal large subunit biogenesis; IEA:InterPro.
DR InterPro; IPR037650; Loc1.
DR PANTHER; PTHR28028; PTHR28028; 1.
PE 3: Inferred from homology;
KW Coiled coil; mRNA transport; Nucleus; Reference proteome;
KW Ribosome biogenesis; Transport.
FT CHAIN 1..189
FT /note="60S ribosomal subunit assembly/export protein loc1"
FT /id="PRO_0000308786"
FT REGION 1..69
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 130..189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 106..160
FT /evidence="ECO:0000255"
FT COMPBIAS 35..67
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 130..181
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 189 AA; 20623 MW; 9F528CFED836545A CRC64;
MAPTKGSGSG KASNKGDAKK SKPLSSASKV NKKTAKRPPP KEVKSKARTE SSLLKKTKKR
EYTEEELGLP KLNAITPVGV VKPKGKKKGK TFVDDAEGMM TILAMVNAEK EGQIESKMMK
ARQLEEIREA KRKEAEARQA QKKSKLEDAK QSIRQKRKHK GGSSETKAEA PTKESSSKSK
GKKKSVAFA
