ID   LOC1_DEBHA              Reviewed;         202 AA.
AC   Q6BRC6;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=60S ribosomal subunit assembly/export protein LOC1;
GN   Name=LOC1; OrderedLocusNames=DEHA2D17402g;
OS   Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990
OS   / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Debaryomyces.
OX   NCBI_TaxID=284592;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Required for efficient assembly and nuclear export of the 60S
CC       ribosomal subunit. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the 66S pre-ribosomal particle. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the LOC1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CR382136; CAG87417.1; -; Genomic_DNA.
DR   RefSeq; XP_459244.1; XM_459244.1.
DR   AlphaFoldDB; Q6BRC6; -.
DR   SMR; Q6BRC6; -.
DR   STRING; 4959.XP_459244.1; -.
DR   PRIDE; Q6BRC6; -.
DR   EnsemblFungi; CAG87417; CAG87417; DEHA2D17402g.
DR   GeneID; 2901629; -.
DR   KEGG; dha:DEHA2D17402g; -.
DR   eggNOG; ENOG502RY6R; Eukaryota.
DR   HOGENOM; CLU_096593_1_0_1; -.
DR   InParanoid; Q6BRC6; -.
DR   OMA; GQIESRM; -.
DR   OrthoDB; 1641629at2759; -.
DR   Proteomes; UP000000599; Chromosome D.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003729; F:mRNA binding; IEA:InterPro.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0042273; P:ribosomal large subunit biogenesis; IEA:InterPro.
DR   InterPro; IPR037650; Loc1.
DR   PANTHER; PTHR28028; PTHR28028; 1.
PE   3: Inferred from homology;
KW   Coiled coil; mRNA transport; Nucleus; Reference proteome;
KW   Ribosome biogenesis; Transport.
FT   CHAIN           1..202
FT                   /note="60S ribosomal subunit assembly/export protein LOC1"
FT                   /id="PRO_0000308793"
FT   REGION          1..43
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          145..202
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          111..176
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        19..40
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        145..171
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        179..193
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   202 AA;  22677 MW;  E7B31B9E7D9F6780 CRC64;
     MAPRQSKTAK RSKVQNKTRT VESEVGSDSA ARNLLMSQPK LTPKSIVKAP SKAAVKKQQA
     KIRLYGARSG KEYREDQLDI PALNKAITPG VKAKKGKKGK KFVEDNDALT LNRLVKSIND
     KYDQANESKL EKSRRLDEIR ELKKQELERK EEQKENKLEG KKNEVKSKAS LARANRRKSA
     KSQKNEESKA ASNKGKKSVS FA