LOC1_NEOFI
ID LOC1_NEOFI Reviewed; 190 AA.
AC A1DLV0;
DT 23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 1.
DT 25-MAY-2022, entry version 59.
DE RecName: Full=60S ribosomal subunit assembly/export protein loc1;
GN Name=loc1; ORFNames=NFIA_051160;
OS Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164
OS / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=331117;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181
RC / WB 181;
RX PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT fumigatus.";
RL PLoS Genet. 4:E1000046-E1000046(2008).
CC -!- FUNCTION: Required for efficient assembly and nuclear export of the 60S
CC ribosomal subunit. {ECO:0000250}.
CC -!- SUBUNIT: Component of the 66S pre-ribosomal particle. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the LOC1 family. {ECO:0000305}.
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DR EMBL; DS027698; EAW15771.1; -; Genomic_DNA.
DR RefSeq; XP_001257668.1; XM_001257667.1.
DR AlphaFoldDB; A1DLV0; -.
DR SMR; A1DLV0; -.
DR STRING; 36630.CADNFIAP00004893; -.
DR EnsemblFungi; EAW15771; EAW15771; NFIA_051160.
DR GeneID; 4584183; -.
DR KEGG; nfi:NFIA_051160; -.
DR VEuPathDB; FungiDB:NFIA_051160; -.
DR eggNOG; ENOG502RY6R; Eukaryota.
DR HOGENOM; CLU_096593_0_0_1; -.
DR OMA; GQIESRM; -.
DR OrthoDB; 1641629at2759; -.
DR Proteomes; UP000006702; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0003729; F:mRNA binding; IEA:InterPro.
DR GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR GO; GO:0042273; P:ribosomal large subunit biogenesis; IEA:InterPro.
DR InterPro; IPR037650; Loc1.
DR PANTHER; PTHR28028; PTHR28028; 1.
PE 3: Inferred from homology;
KW Coiled coil; mRNA transport; Nucleus; Reference proteome;
KW Ribosome biogenesis; Transport.
FT CHAIN 1..190
FT /note="60S ribosomal subunit assembly/export protein loc1"
FT /id="PRO_0000308798"
FT REGION 1..70
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 129..190
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 109..165
FT /evidence="ECO:0000255"
FT COMPBIAS 7..32
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 35..67
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 129..184
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 190 AA; 21032 MW; 5CC6CA4CE3D00420 CRC64;
MAPNKPSVKG KSSSKGDSGK SKPLSSASKV SKKNAKRPPP KEVKSKARTE SSLLKKTKKR
EYTEEELGLP KLNMITPVGV VKPKGKKKGK VFVDDQEGMM TILAMVNAEQ EGHIESKLQK
ARQLEEIREA KRKEAEARHA EKKNKLEEAK QSIRQKRKRK SSGNEDSKSD ASTSKSDSKS
KGKRKSVSFA
