LOC1_PICGU
ID LOC1_PICGU Reviewed; 200 AA.
AC A5DBJ8;
DT 23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 10-FEB-2009, sequence version 2.
DT 03-AUG-2022, entry version 57.
DE RecName: Full=60S ribosomal subunit assembly/export protein LOC1;
GN Name=LOC1; ORFNames=PGUG_00653;
OS Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539
OS / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Meyerozyma.
OX NCBI_TaxID=294746;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324;
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA Birren B.W., Kellis M., Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- FUNCTION: Required for efficient assembly and nuclear export of the 60S
CC ribosomal subunit. {ECO:0000250}.
CC -!- SUBUNIT: Component of the 66S pre-ribosomal particle. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the LOC1 family. {ECO:0000305}.
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DR EMBL; CH408155; EDK36555.2; -; Genomic_DNA.
DR RefSeq; XP_001487276.1; XM_001487226.1.
DR AlphaFoldDB; A5DBJ8; -.
DR SMR; A5DBJ8; -.
DR STRING; 4929.XP_001487276.1; -.
DR EnsemblFungi; EDK36555; EDK36555; PGUG_00653.
DR GeneID; 5129351; -.
DR KEGG; pgu:PGUG_00653; -.
DR VEuPathDB; FungiDB:PGUG_00653; -.
DR eggNOG; ENOG502RY6R; Eukaryota.
DR HOGENOM; CLU_096593_1_0_1; -.
DR InParanoid; A5DBJ8; -.
DR OMA; GQIESRM; -.
DR OrthoDB; 1641629at2759; -.
DR Proteomes; UP000001997; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0003729; F:mRNA binding; IEA:InterPro.
DR GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR GO; GO:0042273; P:ribosomal large subunit biogenesis; IEA:InterPro.
DR InterPro; IPR037650; Loc1.
DR PANTHER; PTHR28028; PTHR28028; 1.
PE 3: Inferred from homology;
KW Coiled coil; mRNA transport; Nucleus; Reference proteome;
KW Ribosome biogenesis; Transport.
FT CHAIN 1..200
FT /note="60S ribosomal subunit assembly/export protein LOC1"
FT /id="PRO_0000308801"
FT REGION 1..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 143..200
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 121..191
FT /evidence="ECO:0000255"
FT COMPBIAS 19..40
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 200 AA; 23090 MW; CB6C1A2789389B61 CRC64;
MATRQSKTAK RNKTQNQKRN VESEVFTDSA ARNLLENQPK LTPKSKVKKP SKLAVKKQQA
KVRLYGAKNG REYKESELQI PVLNKAVVPG VKAKKGKKGK VFVDDNDNLT MERLVKSIND
KYDKVNESKL EKSRRLEEIR EVKRREMEKK EEQKKNKLDD KKKELKNKAS VARANRRKNA
KEAAKEAESD EPRKKKVSFA
