ID   LOC1_PICST              Reviewed;         204 AA.
AC   A3GHA4;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   03-APR-2007, sequence version 1.
DT   25-MAY-2022, entry version 62.
DE   RecName: Full=60S ribosomal subunit assembly/export protein LOC1;
GN   Name=LOC1; ORFNames=PICST_75521;
OS   Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL
OS   Y-11545) (Yeast) (Pichia stipitis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Scheffersomyces.
OX   NCBI_TaxID=322104;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545;
RX   PubMed=17334359; DOI=10.1038/nbt1290;
RA   Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A.,
RA   Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.-S.,
RA   Passoth V., Richardson P.M.;
RT   "Genome sequence of the lignocellulose-bioconverting and xylose-fermenting
RT   yeast Pichia stipitis.";
RL   Nat. Biotechnol. 25:319-326(2007).
CC   -!- FUNCTION: Required for efficient assembly and nuclear export of the 60S
CC       ribosomal subunit. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the 66S pre-ribosomal particle. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the LOC1 family. {ECO:0000305}.
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DR   EMBL; AAVQ01000002; EAZ63021.1; -; Genomic_DNA.
DR   RefSeq; XP_001387044.1; XM_001387007.1.
DR   AlphaFoldDB; A3GHA4; -.
DR   SMR; A3GHA4; -.
DR   STRING; 4924.XP_001387044.1; -.
DR   PRIDE; A3GHA4; -.
DR   EnsemblFungi; EAZ63021; EAZ63021; PICST_75521.
DR   GeneID; 4851653; -.
DR   KEGG; pic:PICST_75521; -.
DR   eggNOG; ENOG502RY6R; Eukaryota.
DR   HOGENOM; CLU_096593_1_0_1; -.
DR   InParanoid; A3GHA4; -.
DR   OMA; RESMNTI; -.
DR   OrthoDB; 1641629at2759; -.
DR   Proteomes; UP000002258; Chromosome 1.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003729; F:mRNA binding; IEA:InterPro.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0042273; P:ribosomal large subunit biogenesis; IEA:InterPro.
DR   InterPro; IPR037650; Loc1.
DR   PANTHER; PTHR28028; PTHR28028; 1.
PE   3: Inferred from homology;
KW   Coiled coil; mRNA transport; Nucleus; Reference proteome;
KW   Ribosome biogenesis; Transport.
FT   CHAIN           1..204
FT                   /note="60S ribosomal subunit assembly/export protein LOC1"
FT                   /id="PRO_0000308802"
FT   REGION          1..52
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          148..204
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          121..178
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        19..40
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        148..171
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        181..197
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   204 AA;  23498 MW;  6B1C5A6822A96515 CRC64;
     MAPRQSKTAK RSKTQNKTRA NESEVFSDAS ARNLMANQPK LTEKSKVKKL SKRVVKKQQA
     KIRLYGAKNG KEYREDQLDI PTLNKAIIPG VRAKKGKKGK KFVDDNDTLT LSRLVKSIND
     KYDVVNESKL EKSRRLEELR ELKKKEIERK EQQKMDKLEG KKSELKNRAS VARSNRRKNA
     KAAKKIEDEE TDQPRKKTKS VSFA