ID   LOC1_SCLS1              Reviewed;         200 AA.
AC   A7E564;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 1.
DT   03-AUG-2022, entry version 53.
DE   RecName: Full=60S ribosomal subunit assembly/export protein loc1;
GN   Name=loc1; ORFNames=SS1G_00436;
OS   Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) (White mold)
OS   (Whetzelinia sclerotiorum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Sclerotiniaceae; Sclerotinia.
OX   NCBI_TaxID=665079;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 18683 / 1980 / Ss-1;
RX   PubMed=21876677; DOI=10.1371/journal.pgen.1002230;
RA   Amselem J., Cuomo C.A., van Kan J.A.L., Viaud M., Benito E.P., Couloux A.,
RA   Coutinho P.M., de Vries R.P., Dyer P.S., Fillinger S., Fournier E.,
RA   Gout L., Hahn M., Kohn L., Lapalu N., Plummer K.M., Pradier J.-M.,
RA   Quevillon E., Sharon A., Simon A., ten Have A., Tudzynski B., Tudzynski P.,
RA   Wincker P., Andrew M., Anthouard V., Beever R.E., Beffa R., Benoit I.,
RA   Bouzid O., Brault B., Chen Z., Choquer M., Collemare J., Cotton P.,
RA   Danchin E.G., Da Silva C., Gautier A., Giraud C., Giraud T., Gonzalez C.,
RA   Grossetete S., Gueldener U., Henrissat B., Howlett B.J., Kodira C.,
RA   Kretschmer M., Lappartient A., Leroch M., Levis C., Mauceli E.,
RA   Neuveglise C., Oeser B., Pearson M., Poulain J., Poussereau N.,
RA   Quesneville H., Rascle C., Schumacher J., Segurens B., Sexton A., Silva E.,
RA   Sirven C., Soanes D.M., Talbot N.J., Templeton M., Yandava C., Yarden O.,
RA   Zeng Q., Rollins J.A., Lebrun M.-H., Dickman M.;
RT   "Genomic analysis of the necrotrophic fungal pathogens Sclerotinia
RT   sclerotiorum and Botrytis cinerea.";
RL   PLoS Genet. 7:E1002230-E1002230(2011).
CC   -!- FUNCTION: Required for efficient assembly and nuclear export of the 60S
CC       ribosomal subunit. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the 66S pre-ribosomal particle. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the LOC1 family. {ECO:0000305}.
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DR   EMBL; CH476621; EDN91036.1; -; Genomic_DNA.
DR   RefSeq; XP_001598350.1; XM_001598300.1.
DR   AlphaFoldDB; A7E564; -.
DR   SMR; A7E564; -.
DR   STRING; 665079.A7E564; -.
DR   PRIDE; A7E564; -.
DR   EnsemblFungi; EDN91036; EDN91036; SS1G_00436.
DR   GeneID; 5494641; -.
DR   KEGG; ssl:SS1G_00436; -.
DR   VEuPathDB; FungiDB:sscle_03g027120; -.
DR   eggNOG; ENOG502RY6R; Eukaryota.
DR   HOGENOM; CLU_096593_0_0_1; -.
DR   InParanoid; A7E564; -.
DR   OMA; RESMNTI; -.
DR   Proteomes; UP000001312; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0030687; C:preribosome, large subunit precursor; IBA:GO_Central.
DR   GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR   GO; GO:0008298; P:intracellular mRNA localization; IBA:GO_Central.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0042273; P:ribosomal large subunit biogenesis; IBA:GO_Central.
DR   InterPro; IPR037650; Loc1.
DR   PANTHER; PTHR28028; PTHR28028; 1.
PE   3: Inferred from homology;
KW   Coiled coil; mRNA transport; Nucleus; Reference proteome;
KW   Ribosome biogenesis; Transport.
FT   CHAIN           1..200
FT                   /note="60S ribosomal subunit assembly/export protein loc1"
FT                   /id="PRO_0000308803"
FT   REGION          1..73
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          138..200
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          130..170
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        1..46
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        138..181
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   200 AA;  22146 MW;  CD185A3BDF8A91F0 CRC64;
     MAPSRTSTVK NKNASKHAAN GSGIRNSKTV SRAQSDGVSK SKGKKATQSK GAPPKPQKQG
     NKMATLKKKR RVYTEKELGI PSLNMITPVG VEKPKGKKKG KVFVDDRESM MTILAMVNAD
     KDGQIESKMM RARQMEEIRE ARKAEHERKQ EMQKNKLKGM KDDLRKKRKR GGDDEGDNVK
     GEALAGTKPL KPKKKTVSFA