ID   LOCU_LOCMI              Reviewed;          55 AA.
AC   P83428;
DT   16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   25-MAY-2022, entry version 37.
DE   RecName: Full=Locustin;
OS   Locusta migratoria (Migratory locust).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Polyneoptera; Orthoptera; Caelifera; Acrididea; Acridomorpha;
OC   Acridoidea; Acrididae; Oedipodinae; Locusta.
OX   NCBI_TaxID=7004 {ECO:0000305};
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, FUNCTION, SUBUNIT, SUBCELLULAR LOCATION, TISSUE
RP   SPECIFICITY, MASS SPECTROMETRY, AND DISULFIDE BONDS.
RC   TISSUE=Hemocyte;
RA   Bulet P., Charlet M., Sabatier-Ehret L.;
RL   Submitted (JUL-2002) to UniProtKB.
CC   -!- FUNCTION: Has antibacterial activity against Gram-positive bacterium
CC       M.luteus. {ECO:0000269|Ref.1, ECO:0000305}.
CC   -!- SUBUNIT: Monomer. {ECO:0000269|Ref.1, ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|Ref.1, ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Stored in hemocyte granules and secreted into the
CC       hemolymph. {ECO:0000269|Ref.1, ECO:0000305}.
CC   -!- MASS SPECTROMETRY: Mass=6052.57; Method=MALDI;
CC       Evidence={ECO:0000269|Ref.1};
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DR   AlphaFoldDB; P83428; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Antibiotic; Antimicrobial; Direct protein sequencing; Disulfide bond;
KW   Immunity; Innate immunity; Secreted.
FT   CHAIN           1..55
FT                   /note="Locustin"
FT                   /id="PRO_0000084457"
FT   DISULFID        5..40
FT                   /evidence="ECO:0000269|Ref.1"
FT   DISULFID        7..36
FT                   /evidence="ECO:0000269|Ref.1"
FT   DISULFID        10..32
FT                   /evidence="ECO:0000269|Ref.1"
FT   DISULFID        17..54
FT                   /evidence="ECO:0000269|Ref.1"
SQ   SEQUENCE   55 AA;  6061 MW;  3A3B17AE7E6D7A8E CRC64;
     ATTGCSCPQC IIFDPICASS YKNGRRGFSS GCHMRCYNRC HGTDYFQISK GSKCI