LOL2_ARATH
ID LOL2_ARATH Reviewed; 155 AA.
AC O65426;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1998, sequence version 1.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=Protein LOL2;
DE AltName: Full=Protein LSD ONE LIKE 2;
DE Short=AtLOL2;
DE AltName: Full=Putative zinc finger LOL2;
GN Name=LOL2; OrderedLocusNames=At4g21610; ORFNames=F17L22.70, F18E5.230;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Shinn P., Chen H., Cheuk R.F., Kim C.J., Ecker J.R.;
RT "Arabidopsis cDNA clones.";
RL Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Shinn P., Chen H., Cheuk R.F., Kim C.J., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, AND IDENTIFICATION BY MASS
RP SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=22223895; DOI=10.1074/mcp.m111.015131;
RA Bienvenut W.V., Sumpton D., Martinez A., Lilla S., Espagne C., Meinnel T.,
RA Giglione C.;
RT "Comparative large-scale characterisation of plant vs. mammal proteins
RT reveals similar and idiosyncratic N-alpha acetylation features.";
RL Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012).
CC -!- FUNCTION: Putative zinc finger that may be involved in programmed cell
CC death and defense response. {ECO:0000250}.
CC -!- INTERACTION:
CC O65426; Q9LJG8: ASIL2; NbExp=3; IntAct=EBI-15192119, EBI-4427947;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
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DR EMBL; AL022603; CAA18725.1; -; Genomic_DNA.
DR EMBL; AL035527; CAB36805.1; -; Genomic_DNA.
DR EMBL; AL161555; CAB81268.1; -; Genomic_DNA.
DR EMBL; CP002687; AEE84480.1; -; Genomic_DNA.
DR EMBL; BT011760; AAS65931.1; -; mRNA.
DR EMBL; BT012384; AAS88774.1; -; mRNA.
DR PIR; T05169; T05169.
DR RefSeq; NP_193892.1; NM_118281.4.
DR AlphaFoldDB; O65426; -.
DR BioGRID; 13537; 9.
DR IntAct; O65426; 10.
DR STRING; 3702.AT4G21610.1; -.
DR iPTMnet; O65426; -.
DR PaxDb; O65426; -.
DR PRIDE; O65426; -.
DR ProteomicsDB; 238584; -.
DR EnsemblPlants; AT4G21610.1; AT4G21610.1; AT4G21610.
DR GeneID; 828248; -.
DR Gramene; AT4G21610.1; AT4G21610.1; AT4G21610.
DR KEGG; ath:AT4G21610; -.
DR Araport; AT4G21610; -.
DR TAIR; locus:2119622; AT4G21610.
DR eggNOG; ENOG502S2GF; Eukaryota.
DR HOGENOM; CLU_109544_0_0_1; -.
DR InParanoid; O65426; -.
DR OMA; GQVKCAS; -.
DR OrthoDB; 1480977at2759; -.
DR PhylomeDB; O65426; -.
DR PRO; PR:O65426; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; O65426; baseline and differential.
DR Genevisible; O65426; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0009617; P:response to bacterium; IEP:TAIR.
DR InterPro; IPR040319; LSD1-like.
DR InterPro; IPR005735; Znf_LSD1.
DR PANTHER; PTHR31747; PTHR31747; 1.
DR Pfam; PF06943; zf-LSD1; 2.
DR TIGRFAMs; TIGR01053; LSD1; 2.
PE 1: Evidence at protein level;
KW Acetylation; Nucleus; Reference proteome.
FT CHAIN 1..155
FT /note="Protein LOL2"
FT /id="PRO_0000408485"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 60..90
FT /note="Putative zinc finger 1"
FT REGION 98..128
FT /note="Putative zinc finger 2"
FT REGION 130..155
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 130..148
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 1
FT /note="N-acetylmethionine"
FT /evidence="ECO:0007744|PubMed:22223895"
SQ SEQUENCE 155 AA; 17248 MW; DB8CB98906FE08B3 CRC64;
MEEIQQQTQK EEQKHREEEE EEEEGPPPGW ESAVLPPPIV TITAAVNPNP TTVEIPEKAQ
MVCGSCRRLL SYLRGSKHVK CSSCQTVNLV LEANQVGQVN CNNCKLLLMY PYGAPAVRCS
SCNSVTDISE NNKRPPWSEQ QGPLKSLSSL RRAEN
