LOLA_AERS4
ID LOLA_AERS4 Reviewed; 202 AA.
AC A4SNK8;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 15-MAY-2007, sequence version 1.
DT 25-MAY-2022, entry version 81.
DE RecName: Full=Outer-membrane lipoprotein carrier protein {ECO:0000255|HAMAP-Rule:MF_00240};
DE Flags: Precursor;
GN Name=lolA {ECO:0000255|HAMAP-Rule:MF_00240}; OrderedLocusNames=ASA_2437;
OS Aeromonas salmonicida (strain A449).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales;
OC Aeromonadaceae; Aeromonas.
OX NCBI_TaxID=382245;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A449;
RX PubMed=18801193; DOI=10.1186/1471-2164-9-427;
RA Reith M.E., Singh R.K., Curtis B., Boyd J.M., Bouevitch A., Kimball J.,
RA Munholland J., Murphy C., Sarty D., Williams J., Nash J.H., Johnson S.C.,
RA Brown L.L.;
RT "The genome of Aeromonas salmonicida subsp. salmonicida A449: insights into
RT the evolution of a fish pathogen.";
RL BMC Genomics 9:427-427(2008).
CC -!- FUNCTION: Participates in the translocation of lipoproteins from the
CC inner membrane to the outer membrane. Only forms a complex with a
CC lipoprotein if the residue after the N-terminal Cys is not an aspartate
CC (The Asp acts as a targeting signal to indicate that the lipoprotein
CC should stay in the inner membrane). {ECO:0000255|HAMAP-Rule:MF_00240}.
CC -!- SUBUNIT: Monomer. {ECO:0000255|HAMAP-Rule:MF_00240}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00240}.
CC -!- SIMILARITY: Belongs to the LolA family. {ECO:0000255|HAMAP-
CC Rule:MF_00240}.
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DR EMBL; CP000644; ABO90480.1; -; Genomic_DNA.
DR RefSeq; WP_005310741.1; NC_009348.1.
DR AlphaFoldDB; A4SNK8; -.
DR SMR; A4SNK8; -.
DR STRING; 382245.ASA_2437; -.
DR EnsemblBacteria; ABO90480; ABO90480; ASA_2437.
DR KEGG; asa:ASA_2437; -.
DR eggNOG; COG2834; Bacteria.
DR HOGENOM; CLU_087560_0_0_6; -.
DR OMA; YDPFVEQ; -.
DR OrthoDB; 1933827at2; -.
DR Proteomes; UP000000225; Chromosome.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0044874; P:lipoprotein localization to outer membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0042953; P:lipoprotein transport; IEA:InterPro.
DR CDD; cd16325; LolA; 1.
DR HAMAP; MF_00240; LolA; 1.
DR InterPro; IPR029046; LolA/LolB/LppX.
DR InterPro; IPR004564; OM_lipoprot_carrier_LolA-like.
DR InterPro; IPR018323; OM_lipoprot_carrier_LolA_Pbac.
DR PANTHER; PTHR35869; PTHR35869; 1.
DR Pfam; PF03548; LolA; 1.
DR SUPFAM; SSF89392; SSF89392; 1.
DR TIGRFAMs; TIGR00547; lolA; 1.
PE 3: Inferred from homology;
KW Chaperone; Periplasm; Protein transport; Signal; Transport.
FT SIGNAL 1..20
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00240"
FT CHAIN 21..202
FT /note="Outer-membrane lipoprotein carrier protein"
FT /id="PRO_0000336651"
SQ SEQUENCE 202 AA; 22880 MW; 02CE67C9AA68C941 CRC64;
MKKQLLIGSV LLVASSQVWA DAASSLKQKL ADVSLFSAKF AQTVYDSKGK ELQKAGGDLL
VQRPNRFNWH TTSPDESLIV ADGKDVWVYD PFVEQVTALK LKDAVLNTPF ILIAGNDDKF
WKHYDVTQEG NVYTVTSRNK DELIASFRVT FDRQNNISRF DVKEAQGQWS EFTLSSFNRK
PVLKGNEFVF KIPKGVELDD QR