LOLA_ALIF1
ID LOLA_ALIF1 Reviewed; 198 AA.
AC Q5E6E5;
DT 02-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT 15-MAR-2005, sequence version 1.
DT 25-MAY-2022, entry version 85.
DE RecName: Full=Outer-membrane lipoprotein carrier protein {ECO:0000255|HAMAP-Rule:MF_00240};
DE Flags: Precursor;
GN Name=lolA {ECO:0000255|HAMAP-Rule:MF_00240}; OrderedLocusNames=VF_0906;
OS Aliivibrio fischeri (strain ATCC 700601 / ES114) (Vibrio fischeri).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Aliivibrio.
OX NCBI_TaxID=312309;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700601 / ES114;
RX PubMed=15703294; DOI=10.1073/pnas.0409900102;
RA Ruby E.G., Urbanowski M., Campbell J., Dunn A., Faini M., Gunsalus R.,
RA Lostroh P., Lupp C., McCann J., Millikan D., Schaefer A., Stabb E.,
RA Stevens A., Visick K., Whistler C., Greenberg E.P.;
RT "Complete genome sequence of Vibrio fischeri: a symbiotic bacterium with
RT pathogenic congeners.";
RL Proc. Natl. Acad. Sci. U.S.A. 102:3004-3009(2005).
CC -!- FUNCTION: Participates in the translocation of lipoproteins from the
CC inner membrane to the outer membrane. Only forms a complex with a
CC lipoprotein if the residue after the N-terminal Cys is not an aspartate
CC (The Asp acts as a targeting signal to indicate that the lipoprotein
CC should stay in the inner membrane). {ECO:0000255|HAMAP-Rule:MF_00240}.
CC -!- SUBUNIT: Monomer. {ECO:0000255|HAMAP-Rule:MF_00240}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_00240}.
CC -!- SIMILARITY: Belongs to the LolA family. {ECO:0000255|HAMAP-
CC Rule:MF_00240}.
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DR EMBL; CP000020; AAW85401.1; -; Genomic_DNA.
DR RefSeq; WP_011261566.1; NC_006840.2.
DR RefSeq; YP_204289.1; NC_006840.2.
DR AlphaFoldDB; Q5E6E5; -.
DR SMR; Q5E6E5; -.
DR STRING; 312309.VF_0906; -.
DR EnsemblBacteria; AAW85401; AAW85401; VF_0906.
DR KEGG; vfi:VF_0906; -.
DR PATRIC; fig|312309.11.peg.902; -.
DR eggNOG; COG2834; Bacteria.
DR HOGENOM; CLU_087560_1_1_6; -.
DR OMA; YDPFVEQ; -.
DR OrthoDB; 1933827at2; -.
DR Proteomes; UP000000537; Chromosome I.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0044874; P:lipoprotein localization to outer membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0042953; P:lipoprotein transport; IEA:InterPro.
DR CDD; cd16325; LolA; 1.
DR HAMAP; MF_00240; LolA; 1.
DR InterPro; IPR029046; LolA/LolB/LppX.
DR InterPro; IPR004564; OM_lipoprot_carrier_LolA-like.
DR InterPro; IPR018323; OM_lipoprot_carrier_LolA_Pbac.
DR PANTHER; PTHR35869; PTHR35869; 1.
DR Pfam; PF03548; LolA; 1.
DR SUPFAM; SSF89392; SSF89392; 1.
DR TIGRFAMs; TIGR00547; lolA; 1.
PE 3: Inferred from homology;
KW Chaperone; Periplasm; Protein transport; Reference proteome; Signal;
KW Transport.
FT SIGNAL 1..17
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00240"
FT CHAIN 18..198
FT /note="Outer-membrane lipoprotein carrier protein"
FT /id="PRO_0000018279"
SQ SEQUENCE 198 AA; 22217 MW; E841FDB058AF64FF CRC64;
MKKFLFSLCL LSSTVLASPQ SELTERLNQN AGFEAGFTQK VLSPEGDVLM QGEGDVKILR
PNLFRWHTQT PDENLLVTDG NTLWYYNPFV EQVTLMGLEK ATTQTPFVLL TRNKASDWDN
YSVSQNGDAF TVSPKADSAV KSEFIVRIQE NGKVTGFSVV EQDGQRSDFD FTKFEAKKPA
KDNFTFAIPD GVDIDDQR