ID   LOLA_COXBU              Reviewed;         211 AA.
AC   P39917;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   03-AUG-2022, entry version 111.
DE   RecName: Full=Outer-membrane lipoprotein carrier protein;
DE   Flags: Precursor;
GN   Name=lolA; OrderedLocusNames=CBU_1190;
OS   Coxiella burnetii (strain RSA 493 / Nine Mile phase I).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Legionellales; Coxiellaceae;
OC   Coxiella.
OX   NCBI_TaxID=227377;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Nine Mile phase I / Bratislava;
RA   Oswald W.;
RL   Thesis (1994), Justus Liebig University / Frankfurt, Germany.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RSA 493 / Nine Mile phase I;
RX   PubMed=12704232; DOI=10.1073/pnas.0931379100;
RA   Seshadri R., Paulsen I.T., Eisen J.A., Read T.D., Nelson K.E., Nelson W.C.,
RA   Ward N.L., Tettelin H., Davidsen T.M., Beanan M.J., DeBoy R.T.,
RA   Daugherty S.C., Brinkac L.M., Madupu R., Dodson R.J., Khouri H.M.,
RA   Lee K.H., Carty H.A., Scanlan D., Heinzen R.A., Thompson H.A., Samuel J.E.,
RA   Fraser C.M., Heidelberg J.F.;
RT   "Complete genome sequence of the Q-fever pathogen, Coxiella burnetii.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:5455-5460(2003).
RN   [3]
RP   IDENTIFICATION BY MASS SPECTROMETRY.
RC   STRAIN=RSA 493 / Nine Mile phase I;
RX   PubMed=19416283; DOI=10.1111/j.1469-0691.2008.02223.x;
RA   Flores-Ramirez G., Toman R., Sekeyova Z., Skultety L.;
RT   "In silico prediction and identification of outer membrane proteins and
RT   lipoproteins from Coxiella burnetii by the mass spectrometry techniques.";
RL   Clin. Microbiol. Infect. 15:196-197(2009).
CC   -!- FUNCTION: Participates in the translocation of lipoproteins from the
CC       inner membrane to the outer membrane. Only forms a complex with a
CC       lipoprotein if the residue after the N-terminal Cys is not an aspartate
CC       (The Asp acts as a targeting signal to indicate that the lipoprotein
CC       should stay in the inner membrane) (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Monomer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the LolA family. {ECO:0000305}.
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DR   EMBL; X75627; CAA53290.1; -; Genomic_DNA.
DR   EMBL; AE016828; AAO90699.1; -; Genomic_DNA.
DR   PIR; S31760; S43133.
DR   RefSeq; NP_820185.1; NC_002971.3.
DR   RefSeq; WP_010958062.1; NC_002971.4.
DR   AlphaFoldDB; P39917; -.
DR   SMR; P39917; -.
DR   STRING; 227377.CBU_1190; -.
DR   EnsemblBacteria; AAO90699; AAO90699; CBU_1190.
DR   GeneID; 1209094; -.
DR   KEGG; cbu:CBU_1190; -.
DR   PATRIC; fig|227377.7.peg.1188; -.
DR   eggNOG; COG2834; Bacteria.
DR   HOGENOM; CLU_087560_0_0_6; -.
DR   OMA; YDPFVEQ; -.
DR   Proteomes; UP000002671; Chromosome.
DR   GO; GO:0030288; C:outer membrane-bounded periplasmic space; IBA:GO_Central.
DR   GO; GO:0044874; P:lipoprotein localization to outer membrane; IBA:GO_Central.
DR   GO; GO:0042953; P:lipoprotein transport; IEA:InterPro.
DR   CDD; cd16325; LolA; 1.
DR   HAMAP; MF_00240; LolA; 1.
DR   InterPro; IPR029046; LolA/LolB/LppX.
DR   InterPro; IPR004564; OM_lipoprot_carrier_LolA-like.
DR   InterPro; IPR018323; OM_lipoprot_carrier_LolA_Pbac.
DR   PANTHER; PTHR35869; PTHR35869; 1.
DR   Pfam; PF03548; LolA; 1.
DR   SUPFAM; SSF89392; SSF89392; 1.
DR   TIGRFAMs; TIGR00547; lolA; 1.
PE   1: Evidence at protein level;
KW   Chaperone; Periplasm; Protein transport; Reference proteome; Signal;
KW   Transport.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000255"
FT   CHAIN           27..211
FT                   /note="Outer-membrane lipoprotein carrier protein"
FT                   /id="PRO_0000018255"
SQ   SEQUENCE   211 AA;  23800 MW;  1DABCC0E4077F211 CRC64;
     MNTIKILIGL LGIFLFSLSG IVSAQSDATT QLSQLLSNFR TYQAKFNQIT FDGQDRVIQQ
     SHGRVMIMRP GRFRWETDSP TKQIIITNGK TLWVYDVDLS QATQQPLAQK TNINPASLLS
     GSVKDLKQKF TITISPTPDA ATFQLVPNLG KSLNFNWIRL KFSKKQLTEM TVLNNLDERS
     IFQFSQIKVN APLSSTLFEF KPSRGIDVVK Q