ID   LOLA_HAEIN              Reviewed;         205 AA.
AC   P45263;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 114.
DE   RecName: Full=Outer-membrane lipoprotein carrier protein;
DE   Flags: Precursor;
GN   Name=lolA; Synonyms=lplA; OrderedLocusNames=HI_1591;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- FUNCTION: Participates in the translocation of lipoproteins from the
CC       inner membrane to the outer membrane. Only forms a complex with a
CC       lipoprotein if the residue after the N-terminal Cys is not an aspartate
CC       (The Asp acts as a targeting signal to indicate that the lipoprotein
CC       should stay in the inner membrane) (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Monomer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the LolA family. {ECO:0000305}.
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DR   EMBL; L42023; AAC23239.1; -; Genomic_DNA.
DR   PIR; G64172; G64172.
DR   RefSeq; NP_439736.1; NC_000907.1.
DR   RefSeq; WP_005693608.1; NC_000907.1.
DR   AlphaFoldDB; P45263; -.
DR   SMR; P45263; -.
DR   STRING; 71421.HI_1591; -.
DR   EnsemblBacteria; AAC23239; AAC23239; HI_1591.
DR   KEGG; hin:HI_1591; -.
DR   PATRIC; fig|71421.8.peg.1665; -.
DR   eggNOG; COG2834; Bacteria.
DR   HOGENOM; CLU_087560_1_1_6; -.
DR   OMA; YDPFVEQ; -.
DR   PhylomeDB; P45263; -.
DR   BioCyc; HINF71421:G1GJ1-1607-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0030288; C:outer membrane-bounded periplasmic space; IBA:GO_Central.
DR   GO; GO:0044874; P:lipoprotein localization to outer membrane; IBA:GO_Central.
DR   GO; GO:0042953; P:lipoprotein transport; IEA:InterPro.
DR   CDD; cd16325; LolA; 1.
DR   HAMAP; MF_00240; LolA; 1.
DR   InterPro; IPR029046; LolA/LolB/LppX.
DR   InterPro; IPR004564; OM_lipoprot_carrier_LolA-like.
DR   InterPro; IPR018323; OM_lipoprot_carrier_LolA_Pbac.
DR   PANTHER; PTHR35869; PTHR35869; 1.
DR   Pfam; PF03548; LolA; 1.
DR   SUPFAM; SSF89392; SSF89392; 1.
DR   TIGRFAMs; TIGR00547; lolA; 1.
PE   3: Inferred from homology;
KW   Chaperone; Periplasm; Protein transport; Reference proteome; Signal;
KW   Transport.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..205
FT                   /note="Outer-membrane lipoprotein carrier protein"
FT                   /id="PRO_0000018260"
SQ   SEQUENCE   205 AA;  23104 MW;  4E650B6D1831787E CRC64;
     MKKTTLKFAA LTLLGLSNLA LADAASELQM RLAKVDVLSA EFVQTVTSGS GKNVQQGSGK
     LQIKRPNLFR METKTPQETQ IISDGKTLWF YDPFVQQVTA QWVKNAVNNT PFVLLTSNDK
     SHWHQYTVTQ QSDTFVLKPT LSTSNIKQFD IRVDANGILR NFSTTEKDGQ TNLYVLRNIT
     NQTLSDSLFQ FKPEKGVEVD DQRKK