ID   LOLA_HELPJ              Reviewed;         184 AA.
AC   Q9ZL58;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   25-MAY-2022, entry version 109.
DE   RecName: Full=Outer-membrane lipoprotein carrier protein;
DE   Flags: Precursor;
GN   Name=lolA; OrderedLocusNames=jhp_0722;
OS   Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=85963;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=J99 / ATCC 700824;
RX   PubMed=9923682; DOI=10.1038/16495;
RA   Alm R.A., Ling L.-S.L., Moir D.T., King B.L., Brown E.D., Doig P.C.,
RA   Smith D.R., Noonan B., Guild B.C., deJonge B.L., Carmel G., Tummino P.J.,
RA   Caruso A., Uria-Nickelsen M., Mills D.M., Ives C., Gibson R., Merberg D.,
RA   Mills S.D., Jiang Q., Taylor D.E., Vovis G.F., Trust T.J.;
RT   "Genomic sequence comparison of two unrelated isolates of the human gastric
RT   pathogen Helicobacter pylori.";
RL   Nature 397:176-180(1999).
CC   -!- FUNCTION: Participates in the translocation of lipoproteins from the
CC       inner membrane to the outer membrane. Only forms a complex with a
CC       lipoprotein if the residue after the N-terminal Cys is not an aspartate
CC       (The Asp acts as a targeting signal to indicate that the lipoprotein
CC       should stay in the inner membrane) (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Monomer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the LolA family. {ECO:0000305}.
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DR   EMBL; AE001439; AAD06296.1; -; Genomic_DNA.
DR   PIR; B71897; B71897.
DR   RefSeq; WP_000643052.1; NZ_CP011330.1.
DR   AlphaFoldDB; Q9ZL58; -.
DR   SMR; Q9ZL58; -.
DR   STRING; 85963.jhp_0722; -.
DR   EnsemblBacteria; AAD06296; AAD06296; jhp_0722.
DR   KEGG; hpj:jhp_0722; -.
DR   PATRIC; fig|85963.30.peg.254; -.
DR   eggNOG; COG2834; Bacteria.
DR   OMA; IYMNDKE; -.
DR   Proteomes; UP000000804; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0044874; P:lipoprotein localization to outer membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0042953; P:lipoprotein transport; IEA:InterPro.
DR   CDD; cd16325; LolA; 1.
DR   HAMAP; MF_00240; LolA; 1.
DR   InterPro; IPR029046; LolA/LolB/LppX.
DR   InterPro; IPR004564; OM_lipoprot_carrier_LolA-like.
DR   InterPro; IPR018323; OM_lipoprot_carrier_LolA_Pbac.
DR   PANTHER; PTHR35869; PTHR35869; 1.
DR   Pfam; PF03548; LolA; 1.
DR   SUPFAM; SSF89392; SSF89392; 1.
PE   3: Inferred from homology;
KW   Chaperone; Periplasm; Protein transport; Signal; Transport.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255"
FT   CHAIN           20..184
FT                   /note="Outer-membrane lipoprotein carrier protein"
FT                   /id="PRO_0000018263"
SQ   SEQUENCE   184 AA;  21399 MW;  8941A063F0C2FF57 CRC64;
     MKAFLKICMV LIFVGVAHAK NPLTLSKEEE VLQNLQSFSA HFKQVLKNEK PLVYYGVLKA
     KAPNWALWVY EKPLKKEIYM NDKEVVVYEP NLFQATITPL KDKTDFFTIL KQLKKQTDGS
     FKTTINKTTY RLVFKDGKPF SLEFKDDMNN LVTITFSQAE INPKIPNEIF VFNPKDENID
     IVRQ