ID   LOLB_SALTY              Reviewed;         207 AA.
AC   P30752;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 2.
DT   03-AUG-2022, entry version 128.
DE   RecName: Full=Outer-membrane lipoprotein LolB;
DE   Flags: Precursor;
GN   Name=lolB; Synonyms=hemM; OrderedLocusNames=STM1778;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7679718; DOI=10.1099/00221287-139-2-259;
RA   Post D.A., Hove-Jensen B., Switzer R.L.;
RT   "Characterization of the hemA-prs region of the Escherichia coli and
RT   Salmonella typhimurium chromosomes: identification of two open reading
RT   frames and implications for prs expression.";
RL   J. Gen. Microbiol. 139:259-266(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-139.
RX   PubMed=2544564; DOI=10.1128/jb.171.7.3948-3960.1989;
RA   Elliott T.;
RT   "Cloning, genetic characterization, and nucleotide sequence of the hemA-
RT   prfA operon of Salmonella typhimurium.";
RL   J. Bacteriol. 171:3948-3960(1989).
CC   -!- FUNCTION: Plays a critical role in the incorporation of lipoproteins in
CC       the outer membrane after they are released by the LolA protein.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Monomer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000250}; Lipid-anchor
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the LolB family. {ECO:0000305}.
CC   -!- CAUTION: Was originally thought to be involved in delta-aminolevulinic
CC       acid biosynthesis. {ECO:0000305}.
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DR   EMBL; M77236; AAA27194.1; -; Genomic_DNA.
DR   EMBL; AE006468; AAL20693.1; -; Genomic_DNA.
DR   EMBL; J04243; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PIR; S27731; S27731.
DR   RefSeq; NP_460734.1; NC_003197.2.
DR   RefSeq; WP_000174484.1; NC_003197.2.
DR   AlphaFoldDB; P30752; -.
DR   SMR; P30752; -.
DR   STRING; 99287.STM1778; -.
DR   PaxDb; P30752; -.
DR   EnsemblBacteria; AAL20693; AAL20693; STM1778.
DR   GeneID; 1253297; -.
DR   KEGG; stm:STM1778; -.
DR   PATRIC; fig|99287.12.peg.1874; -.
DR   HOGENOM; CLU_092816_1_1_6; -.
DR   OMA; YQTRGSF; -.
DR   PhylomeDB; P30752; -.
DR   BioCyc; SENT99287:STM1778-MON; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0044874; P:lipoprotein localization to outer membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   CDD; cd16326; LolB; 1.
DR   HAMAP; MF_00233; LolB; 1.
DR   InterPro; IPR029046; LolA/LolB/LppX.
DR   InterPro; IPR004565; OM_lipoprot_LolB.
DR   Pfam; PF03550; LolB; 1.
DR   SUPFAM; SSF89392; SSF89392; 1.
DR   TIGRFAMs; TIGR00548; lolB; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Chaperone; Lipoprotein; Membrane; Palmitate;
KW   Protein transport; Reference proteome; Signal; Transport.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..207
FT                   /note="Outer-membrane lipoprotein LolB"
FT                   /id="PRO_0000018311"
FT   LIPID           22
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255"
FT   LIPID           22
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   207 AA;  23686 MW;  45483A05FDA4F4DB CRC64;
     MTLPDFRLIR LLPLASLVLT ACTLPGHKGP GKSPDSPQWR QHQQEVRHLN QYQTRGAFAY
     ISDDQKVYAR FFWQQTGQDR YRLLLTNPLG STELELNAQP GNVQLVDNKG QRYTADDAEE
     MIGKLTGMPI PLNSLRQWIL GLPGDATDYK LDDQYRLSEV NYRQDGKNWK VVYGGYDSKT
     QPAMPANMEL SDGSQRIKLK MDNWIVK