ID   LOLB_VIBCH              Reviewed;         205 AA.
AC   P57070; Q9APZ3;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   10-OCT-2002, sequence version 2.
DT   25-MAY-2022, entry version 117.
DE   RecName: Full=Outer-membrane lipoprotein LolB;
DE   Flags: Precursor;
GN   Name=lolB; Synonyms=hemM; OrderedLocusNames=VC_2181;
OS   Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=243277;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Bengal;
RA   Ravichandran M., Lalitha P., Tang T.H., Chan Y.Y., Johari M.R.,
RA   Zainuddin Z.F.;
RT   "Cloning and characterization of hemA and hemM gene of Vibrio cholerae
RT   (Bengal strain).";
RL   Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39315 / El Tor Inaba N16961;
RX   PubMed=10952301; DOI=10.1038/35020000;
RA   Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA   Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA   Nelson K.E., Read T.D., Tettelin H., Richardson D.L., Ermolaeva M.D.,
RA   Vamathevan J.J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.A.,
RA   Utterback T.R., Fleischmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA   Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT   "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT   cholerae.";
RL   Nature 406:477-483(2000).
CC   -!- FUNCTION: Plays a critical role in the incorporation of lipoproteins in
CC       the outer membrane after they are released by the LolA protein.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Monomer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000250}; Lipid-anchor
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the LolB family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAF95326.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AF227752; AAK00700.1; -; Genomic_DNA.
DR   EMBL; AE003852; AAF95326.1; ALT_INIT; Genomic_DNA.
DR   PIR; D82109; D82109.
DR   RefSeq; NP_231812.1; NC_002505.1.
DR   RefSeq; WP_000993150.1; NZ_LT906614.1.
DR   AlphaFoldDB; P57070; -.
DR   SMR; P57070; -.
DR   STRING; 243277.VC_2181; -.
DR   DNASU; 2613317; -.
DR   EnsemblBacteria; AAF95326; AAF95326; VC_2181.
DR   GeneID; 57740793; -.
DR   KEGG; vch:VC_2181; -.
DR   PATRIC; fig|243277.26.peg.2079; -.
DR   eggNOG; COG3017; Bacteria.
DR   HOGENOM; CLU_092816_1_0_6; -.
DR   OMA; YQTRGSF; -.
DR   Proteomes; UP000000584; Chromosome 1.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0044874; P:lipoprotein localization to outer membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   CDD; cd16326; LolB; 1.
DR   HAMAP; MF_00233; LolB; 1.
DR   InterPro; IPR029046; LolA/LolB/LppX.
DR   InterPro; IPR004565; OM_lipoprot_LolB.
DR   Pfam; PF03550; LolB; 1.
DR   SUPFAM; SSF89392; SSF89392; 1.
DR   TIGRFAMs; TIGR00548; lolB; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Chaperone; Lipoprotein; Membrane; Palmitate;
KW   Protein transport; Reference proteome; Signal; Transport.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..205
FT                   /note="Outer-membrane lipoprotein LolB"
FT                   /id="PRO_0000018314"
FT   LIPID           21
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255"
FT   LIPID           21
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   205 AA;  23619 MW;  89B6959C0C5542A7 CRC64;
     MNALVRRLLP GLASLLLLAG CATAPLQPVN VQWQSHQVTL EQIQHYQLTG KLGYIAPDQR
     QSFNFQWQKS PQKLSLRLSN FLGQTVLNLQ VDEQGARVET YDDQIYRDQD AQSLIRNLTG
     LDIPVEQLED WILGLPTQAT HYELNEQNTL ATLTKLASTE EWHVEYQRYQ AIEWQHQPIP
     LPDKLKLQQN KTSIQLVISQ WTLLP