ID   LOLC_BUCAI              Reviewed;         399 AA.
AC   P57382;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2000, sequence version 1.
DT   25-MAY-2022, entry version 101.
DE   RecName: Full=Lipoprotein-releasing system transmembrane protein LolC;
GN   Name=lolC; OrderedLocusNames=BU295;
OS   Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon
OS   pisum symbiotic bacterium).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Buchnera.
OX   NCBI_TaxID=107806;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=APS;
RX   PubMed=10993077; DOI=10.1038/35024074;
RA   Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.;
RT   "Genome sequence of the endocellular bacterial symbiont of aphids Buchnera
RT   sp. APS.";
RL   Nature 407:81-86(2000).
CC   -!- FUNCTION: Part of an ATP-dependent transport system responsible for the
CC       release of lipoproteins targeted to the outer membrane from the inner
CC       membrane. Such a release is dependent of the sorting-signal (absence of
CC       an Asp at position 2 of the mature lipoprotein) and of LolA (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ABC-4 integral membrane protein family.
CC       LolC/E subfamily. {ECO:0000305}.
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DR   EMBL; BA000003; BAB13005.1; -; Genomic_DNA.
DR   RefSeq; NP_240119.1; NC_002528.1.
DR   RefSeq; WP_009874249.1; NC_002528.1.
DR   AlphaFoldDB; P57382; -.
DR   SMR; P57382; -.
DR   STRING; 107806.10038970; -.
DR   EnsemblBacteria; BAB13005; BAB13005; BAB13005.
DR   KEGG; buc:BU295; -.
DR   PATRIC; fig|107806.10.peg.305; -.
DR   eggNOG; COG4591; Bacteria.
DR   HOGENOM; CLU_000604_8_1_6; -.
DR   OMA; GWWQQNG; -.
DR   Proteomes; UP000001806; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0042953; P:lipoprotein transport; IEA:InterPro.
DR   InterPro; IPR011925; LolCE_TM.
DR   InterPro; IPR025857; MacB_PCD.
DR   Pfam; PF12704; MacB_PCD; 1.
DR   TIGRFAMs; TIGR02212; lolCE; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..399
FT                   /note="Lipoprotein-releasing system transmembrane protein
FT                   LolC"
FT                   /id="PRO_0000201808"
FT   TRANSMEM        25..45
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        266..286
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        312..332
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        358..378
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   399 AA;  46185 MW;  1D6472066705F1D1 CRC64;
     MYKPISLFIA LRYLWNTHLP NFKKIITILS IIGISITTAS LIIITSIING SEKNFEKNIL
     SFIPHLIITN KNQCIKKDQF PENILKLNNI KNISDLISKE IIVQSKNDIS MAEVIGIDHT
     NYYNIHNYNI KSVLKTLKPG YYNIIIGKQL ARKLNVFIGD RLKLIFLSNT KNFFSGEIFK
     QRTFKIINFF STKKEVDYYQ ILMNKEDSLN FLNYSKDYVT GWRVWLKNPL SLNVNEIKKI
     THPLFLLDWT TQKGELFKAM KIEKYIMFLF LFLVLLVSIL NIVVILTICT VEKQNAVAIL
     QTQGLLNCKI MLIFIIFGSS TAIIGNILGT LISLTLIIQN DFLKFFINIF IDETNIPIIV
     IPYQIFFINI TITLFTILST LYPSWKAIQL KPSRILSNE