LOLC_XYLFA
ID LOLC_XYLFA Reviewed; 413 AA.
AC Q9PEF2;
DT 01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 25-MAY-2022, entry version 103.
DE RecName: Full=Lipoprotein-releasing system transmembrane protein LolC;
GN Name=lolC; OrderedLocusNames=XF_1076;
OS Xylella fastidiosa (strain 9a5c).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Xylella.
OX NCBI_TaxID=160492;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=9a5c;
RX PubMed=10910347; DOI=10.1038/35018003;
RA Simpson A.J.G., Reinach F.C., Arruda P., Abreu F.A., Acencio M.,
RA Alvarenga R., Alves L.M.C., Araya J.E., Baia G.S., Baptista C.S.,
RA Barros M.H., Bonaccorsi E.D., Bordin S., Bove J.M., Briones M.R.S.,
RA Bueno M.R.P., Camargo A.A., Camargo L.E.A., Carraro D.M., Carrer H.,
RA Colauto N.B., Colombo C., Costa F.F., Costa M.C.R., Costa-Neto C.M.,
RA Coutinho L.L., Cristofani M., Dias-Neto E., Docena C., El-Dorry H.,
RA Facincani A.P., Ferreira A.J.S., Ferreira V.C.A., Ferro J.A., Fraga J.S.,
RA Franca S.C., Franco M.C., Frohme M., Furlan L.R., Garnier M., Goldman G.H.,
RA Goldman M.H.S., Gomes S.L., Gruber A., Ho P.L., Hoheisel J.D.,
RA Junqueira M.L., Kemper E.L., Kitajima J.P., Krieger J.E., Kuramae E.E.,
RA Laigret F., Lambais M.R., Leite L.C.C., Lemos E.G.M., Lemos M.V.F.,
RA Lopes S.A., Lopes C.R., Machado J.A., Machado M.A., Madeira A.M.B.N.,
RA Madeira H.M.F., Marino C.L., Marques M.V., Martins E.A.L., Martins E.M.F.,
RA Matsukuma A.Y., Menck C.F.M., Miracca E.C., Miyaki C.Y.,
RA Monteiro-Vitorello C.B., Moon D.H., Nagai M.A., Nascimento A.L.T.O.,
RA Netto L.E.S., Nhani A. Jr., Nobrega F.G., Nunes L.R., Oliveira M.A.,
RA de Oliveira M.C., de Oliveira R.C., Palmieri D.A., Paris A., Peixoto B.R.,
RA Pereira G.A.G., Pereira H.A. Jr., Pesquero J.B., Quaggio R.B.,
RA Roberto P.G., Rodrigues V., de Rosa A.J.M., de Rosa V.E. Jr., de Sa R.G.,
RA Santelli R.V., Sawasaki H.E., da Silva A.C.R., da Silva A.M.,
RA da Silva F.R., Silva W.A. Jr., da Silveira J.F., Silvestri M.L.Z.,
RA Siqueira W.J., de Souza A.A., de Souza A.P., Terenzi M.F., Truffi D.,
RA Tsai S.M., Tsuhako M.H., Vallada H., Van Sluys M.A., Verjovski-Almeida S.,
RA Vettore A.L., Zago M.A., Zatz M., Meidanis J., Setubal J.C.;
RT "The genome sequence of the plant pathogen Xylella fastidiosa.";
RL Nature 406:151-159(2000).
CC -!- FUNCTION: Part of an ATP-dependent transport system responsible for the
CC release of lipoproteins targeted to the outer membrane from the inner
CC membrane. Such a release is dependent of the sorting-signal (absence of
CC an Asp at position 2 of the mature lipoprotein) and of LolA (By
CC similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the ABC-4 integral membrane protein family.
CC LolC/E subfamily. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AE003849; AAF83886.1; -; Genomic_DNA.
DR PIR; A82726; A82726.
DR RefSeq; WP_010893595.1; NC_002488.3.
DR AlphaFoldDB; Q9PEF2; -.
DR SMR; Q9PEF2; -.
DR STRING; 160492.XF_1076; -.
DR EnsemblBacteria; AAF83886; AAF83886; XF_1076.
DR KEGG; xfa:XF_1076; -.
DR eggNOG; COG4591; Bacteria.
DR HOGENOM; CLU_000604_8_1_6; -.
DR OMA; GWWQQNG; -.
DR Proteomes; UP000000812; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0042953; P:lipoprotein transport; IEA:InterPro.
DR InterPro; IPR003838; ABC3_permease_dom.
DR InterPro; IPR011925; LolCE_TM.
DR InterPro; IPR025857; MacB_PCD.
DR Pfam; PF02687; FtsX; 1.
DR Pfam; PF12704; MacB_PCD; 1.
DR TIGRFAMs; TIGR02212; lolCE; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..413
FT /note="Lipoprotein-releasing system transmembrane protein
FT LolC"
FT /id="PRO_0000201816"
FT TRANSMEM 22..42
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 269..289
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 322..342
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 379..399
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 413 AA; 45315 MW; 22D5D4DA67E9643E CRC64;
MFNPLSVAIG LRYLRAKRRN GFISFISMAS ILGIALGVTV LITTLAVMSG FQKEIRDRLL
QMAAHATVSA QGAPMHDWQH AVALAMTDPR VAGAAPYIES EALLQGERHQ PAMMRGIVPN
QEDKVSVLAQ KLKVGSIDSL KPGEYNILLG KELALWLGVD VGDSVIVLLS QTQTTPVGTM
PRMKRFTVSG LFEVGYNEID RGLAVVNMED MQKVMRMDGV TGVRLKLHDM DHAWDVARDL
AVRLNGPYLV SDWTRENANL YSSLKMEKTV MGILLSLIIA MGAFNLVSSQ VMLVTDKQAD
IAILRTLGLS PAGVMRVFMV QGSLIGIIGT LSGVIGGVVL TWNLERILKL IESTFNITLL
PEDVYYITGL PTDMQFPDVV VITLMALVMS FIATLYPAWR AARIQPAEAL RYE
