LOLD_ACIAD
ID LOLD_ACIAD Reviewed; 228 AA.
AC Q9EYM2; Q6F967;
DT 24-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 120.
DE RecName: Full=Lipoprotein-releasing system ATP-binding protein LolD {ECO:0000255|HAMAP-Rule:MF_01708};
DE EC=7.6.2.- {ECO:0000255|HAMAP-Rule:MF_01708};
GN Name=lolD {ECO:0000255|HAMAP-Rule:MF_01708}; OrderedLocusNames=ACIAD2640;
OS Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC Acinetobacter.
OX NCBI_TaxID=62977;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=11425734; DOI=10.1128/aem.67.7.3140-3148.2001;
RA Friedrich A., Hartsch T., Averhoff B.;
RT "Natural transformation in mesophilic and thermophilic bacteria:
RT identification and characterization of novel, closely related competence
RT genes in Acinetobacter sp. strain BD413 and Thermus thermophilus HB27.";
RL Appl. Environ. Microbiol. 67:3140-3148(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33305 / BD413 / ADP1;
RX PubMed=15514110; DOI=10.1093/nar/gkh910;
RA Barbe V., Vallenet D., Fonknechten N., Kreimeyer A., Oztas S., Labarre L.,
RA Cruveiller S., Robert C., Duprat S., Wincker P., Ornston L.N.,
RA Weissenbach J., Marliere P., Cohen G.N., Medigue C.;
RT "Unique features revealed by the genome sequence of Acinetobacter sp. ADP1,
RT a versatile and naturally transformation competent bacterium.";
RL Nucleic Acids Res. 32:5766-5779(2004).
CC -!- FUNCTION: Part of the ABC transporter complex LolCDE involved in the
CC translocation of mature outer membrane-directed lipoproteins, from the
CC inner membrane to the periplasmic chaperone, LolA. Responsible for the
CC formation of the LolA-lipoprotein complex in an ATP-dependent manner.
CC {ECO:0000255|HAMAP-Rule:MF_01708}.
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (LolD) and
CC two transmembrane proteins (LolC and LolE). {ECO:0000255|HAMAP-
CC Rule:MF_01708}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01708}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01708}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. Lipoprotein
CC translocase (TC 3.A.1.125) family. {ECO:0000255|HAMAP-Rule:MF_01708}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAG69398.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AF320001; AAG34709.1; -; Genomic_DNA.
DR EMBL; CR543861; CAG69398.1; ALT_INIT; Genomic_DNA.
DR RefSeq; WP_004928867.1; NC_005966.1.
DR AlphaFoldDB; Q9EYM2; -.
DR SMR; Q9EYM2; -.
DR STRING; 62977.ACIAD2640; -.
DR EnsemblBacteria; CAG69398; CAG69398; ACIAD2640.
DR GeneID; 45234919; -.
DR KEGG; aci:ACIAD2640; -.
DR eggNOG; COG1136; Bacteria.
DR HOGENOM; CLU_000604_1_22_6; -.
DR OrthoDB; 1181903at2; -.
DR BioCyc; ASP62977:ACIAD_RS12010-MON; -.
DR Proteomes; UP000000430; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0042953; P:lipoprotein transport; IEA:InterPro.
DR CDD; cd03255; ABC_MJ0796_LolCDE_FtsE; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR015854; ABC_transpr_LolD.
DR InterPro; IPR017911; MacB_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR24220:SF654; PTHR24220:SF654; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR PROSITE; PS51244; LOLD; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cell inner membrane; Cell membrane; Membrane;
KW Nucleotide-binding; Reference proteome; Translocase; Transport.
FT CHAIN 1..228
FT /note="Lipoprotein-releasing system ATP-binding protein
FT LolD"
FT /id="PRO_0000092415"
FT DOMAIN 6..225
FT /note="ABC transporter"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01708"
FT BINDING 42..49
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01708"
SQ SEQUENCE 228 AA; 25322 MW; 6EFB357F28852129 CRC64;
MSKIVLEAKD VYKHFTDGKS TVEVIKGLSL KIAAGEFVSI VGASGSGKST LLHILGGLDQ
PTQGQVFLNE QRFDNLGEAE RGFKRNQYLG FVYQFHHLLP EFSALENVAM PLMLRADTNY
KEVKQQAEHL LDRVGLSHRL THKPGELSGG ERQRVALARA LVARPAVMLA DEPTGNLDRK
TAFGIFELLS DLKQEFNMAM LIVTHDEQLA QSADSILHMQ DGLWVDHS
