ID   LOVG_ANOGA              Reviewed;         266 AA.
AC   Q7QBJ0;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 3.
DT   03-AUG-2022, entry version 83.
DE   RecName: Full=Esterase AGAP003155;
DE            EC=3.1.2.- {ECO:0000305};
GN   ORFNames=AGAP003155;
OS   Anopheles gambiae (African malaria mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=7165;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PEST;
RX   PubMed=12364791; DOI=10.1126/science.1076181;
RA   Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R.,
RA   Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R.,
RA   Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., Lai Z.,
RA   Kraft C.L., Abril J.F., Anthouard V., Arensburger P., Atkinson P.W.,
RA   Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C.,
RA   Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K.,
RA   Christophides G.K., Chrystal M.A.M., Clamp M., Cravchik A., Curwen V.,
RA   Dana A., Delcher A., Dew I., Evans C.A., Flanigan M.,
RA   Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R.,
RA   Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J.,
RA   Jaillon O., Ke Z., Kodira C.D., Kokoza E., Koutsos A., Letunic I.,
RA   Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., Lopez J.R., Malek J.A.,
RA   McIntosh T.C., Meister S., Miller J.R., Mobarry C., Mongin E., Murphy S.D.,
RA   O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H.,
RA   Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J.,
RA   Thomasova D., Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B.,
RA   Wang A.H., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M.,
RA   Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I.,
RA   Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J.,
RA   Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M.,
RA   Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C.,
RA   Collins F.H., Hoffman S.L.;
RT   "The genome sequence of the malaria mosquito Anopheles gambiae.";
RL   Science 298:129-149(2002).
CC   -!- SIMILARITY: Belongs to the LovG family. {ECO:0000305}.
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DR   EMBL; AAAB01008879; EAA08462.5; -; Genomic_DNA.
DR   RefSeq; XP_312845.5; XM_312845.5.
DR   AlphaFoldDB; Q7QBJ0; -.
DR   SMR; Q7QBJ0; -.
DR   STRING; 7165.AGAP003155-PA; -.
DR   ESTHER; anoga-q7qbj0; FSH1.
DR   PaxDb; Q7QBJ0; -.
DR   GeneID; 1273826; -.
DR   KEGG; aga:AgaP_AGAP003155; -.
DR   CTD; 1273826; -.
DR   VEuPathDB; VectorBase:AGAP003155; -.
DR   eggNOG; KOG2551; Eukaryota.
DR   HOGENOM; CLU_051938_2_3_1; -.
DR   InParanoid; Q7QBJ0; -.
DR   OMA; EEPTVCR; -.
DR   OrthoDB; 1190789at2759; -.
DR   PhylomeDB; Q7QBJ0; -.
DR   Proteomes; UP000007062; Chromosome 2R.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0016787; F:hydrolase activity; IBA:GO_Central.
DR   GO; GO:0032526; P:response to retinoic acid; IBA:GO_Central.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR005645; FSH_dom.
DR   Pfam; PF03959; FSH1; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Reference proteome.
FT   CHAIN           1..266
FT                   /note="Esterase AGAP003155"
FT                   /id="PRO_0000300885"
FT   REGION          231..266
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        231..250
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   ACT_SITE        114
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250|UniProtKB:P38777"
FT   ACT_SITE        172
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250|UniProtKB:P38777"
FT   ACT_SITE        199
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250|UniProtKB:P38777"
SQ   SEQUENCE   266 AA;  29496 MW;  EABF34B374C20349 CRC64;
     MSKVSGAGEE KLKVLALHGY RQNADSFKSK LGSFRKMLNK YVEFVFVSAP HPAAPLEAVG
     GEPDPNQRSW WFNKDDRTFK GTNQGGPAYG FDESLRLVER TWQAEGCHGL LGFSQGACFV
     GLLCDLSARG MTTMKPQFAV VASGFRSGSL VHLNYYENKV QIPSLHIFGE TDEIITKDMS
     EALAETFLDP EVVTHPGGHY FPAQASLKET YVDFFRDQLQ QHLEAKELQN ATEENSFHLE
     GQEEAEESAL QPVHEGLQNG SDSDSD