ID   LOVG_DROPS              Reviewed;         289 AA.
AC   Q29BR3;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   04-APR-2006, sequence version 1.
DT   03-AUG-2022, entry version 68.
DE   RecName: Full=Esterase GA18864;
DE            EC=3.1.2.- {ECO:0000305};
GN   ORFNames=GA18864;
OS   Drosophila pseudoobscura pseudoobscura (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=46245;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MV2-25 / Tucson 14011-0121.94;
RX   PubMed=15632085; DOI=10.1101/gr.3059305;
RA   Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S.,
RA   Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P., Couronne O.,
RA   Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J., van Batenburg M.F.,
RA   Howells S.L., Scherer S.E., Sodergren E., Matthews B.B., Crosby M.A.,
RA   Schroeder A.J., Ortiz-Barrientos D., Rives C.M., Metzker M.L., Muzny D.M.,
RA   Scott G., Steffen D., Wheeler D.A., Worley K.C., Havlak P., Durbin K.J.,
RA   Egan A., Gill R., Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y.,
RA   Waldron L., Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.F.,
RA   Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.M.,
RA   Weinstock G.M., Gibbs R.A.;
RT   "Comparative genome sequencing of Drosophila pseudoobscura: chromosomal,
RT   gene, and cis-element evolution.";
RL   Genome Res. 15:1-18(2005).
CC   -!- SIMILARITY: Belongs to the LovG family. {ECO:0000305}.
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DR   EMBL; CM000070; EAL26934.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q29BR3; -.
DR   SMR; Q29BR3; -.
DR   STRING; 7237.FBpp0282814; -.
DR   ESTHER; drops-q29br3; FSH1.
DR   eggNOG; KOG2551; Eukaryota.
DR   HOGENOM; CLU_051938_2_3_1; -.
DR   InParanoid; Q29BR3; -.
DR   OMA; EEPTVCR; -.
DR   PhylomeDB; Q29BR3; -.
DR   Proteomes; UP000001819; Genome assembly.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR005645; FSH_dom.
DR   Pfam; PF03959; FSH1; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Reference proteome.
FT   CHAIN           1..289
FT                   /note="Esterase GA18864"
FT                   /id="PRO_0000300882"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          253..289
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   ACT_SITE        133
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250|UniProtKB:P38777"
FT   ACT_SITE        191
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250|UniProtKB:P38777"
FT   ACT_SITE        218
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250|UniProtKB:P38777"
SQ   SEQUENCE   289 AA;  31368 MW;  49B8DD4829D19E12 CRC64;
     MTNNDAAVEA PSSSRASSSK QQPKLEITEK VRVLCLHGYR QDGDAFKNKL GSFRKFTSKY
     AEFVFISAPH IAAPLESAAE PVPEQRSWWA NKDDGTFKGT NKGGPAFGFQ DSLRLVEEAW
     KTQGPFQGLL GFSQGACFVG LICGLAKKKL TSIRPEFAVL SSGFVSGSLV HMSAYEEPVS
     IPTLHIYGSS DEIIPKDMSA LLASHFKNVE VLEHGGGHYF PATAQQKQTY INFFQDRLQE
     YLEHLELQQS SSVSFIESGA EDNDDDGDAN DAEVAAATAA AGSDLDDSD