LP61_EIMTE
ID LP61_EIMTE Reviewed; 255 AA.
AC P15714;
DT 01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT 01-APR-1990, sequence version 1.
DT 25-MAY-2022, entry version 52.
DE RecName: Full=Antigen LPMC-61;
DE Flags: Fragment;
OS Eimeria tenella (Coccidian parasite).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Eimeriidae; Eimeria.
OX NCBI_TaxID=5802;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Sporozoite;
RX PubMed=2200963; DOI=10.1016/0166-6851(90)90096-5;
RA Ko C., Smith C.K. II, McDonell M.;
RT "Identification and characterization of a target antigen of a monoclonal
RT antibody directed against Eimeria tenella merozoites.";
RL Mol. Biochem. Parasitol. 41:53-64(1990).
CC -!- FUNCTION: Unknown. The Gln-rich tandem repeats may be important for an
CC unknown aspect of the parasitic life cycle. May be an important
CC immunogen.
CC -!- SUBUNIT: May be covalently linked by disulfide bonds to other
CC polypeptides to form the 80 kDa antigen.
CC -!- DEVELOPMENTAL STAGE: Present in all stages throughout the sporulation
CC of the oocysts and in the sporozoites following excystation.
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DR EMBL; M30933; AAA29079.1; -; mRNA.
DR PIR; A60637; A60637.
DR AlphaFoldDB; P15714; -.
DR PRIDE; P15714; -.
DR VEuPathDB; ToxoDB:ETH2_0106900; -.
DR VEuPathDB; ToxoDB:ETH_00042955; -.
DR GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
PE 2: Evidence at transcript level;
KW Disulfide bond; Repeat; Sporozoite; Sporulation.
FT CHAIN <1..>255
FT /note="Antigen LPMC-61"
FT /id="PRO_0000084461"
FT REPEAT 18..48
FT /note="1"
FT REPEAT 49..57
FT /note="2"
FT REPEAT 58..65
FT /note="3"
FT REPEAT 66..78
FT /note="4"
FT REPEAT 79..90
FT /note="5"
FT REPEAT 91..103
FT /note="6"
FT REPEAT 104..140
FT /note="7"
FT REPEAT 141..152
FT /note="8"
FT REPEAT 153..164
FT /note="9"
FT REPEAT 165..172
FT /note="10"
FT REPEAT 173..192
FT /note="11"
FT REPEAT 193..210
FT /note="12"
FT REGION 18..210
FT /note="12 X approximate tandem repeats, Gln-rich"
FT REGION 18..90
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 149..224
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 149..213
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT NON_TER 255
SQ SEQUENCE 255 AA; 31267 MW; 8C5E6005FFFC2DB3 CRC64;
LRLLLKLLLL LLGQQKHWPE RQQQQQPQPW LDRQQQQQQH NQQLQKQQWP EGQRQQLWPE
QQQQQWPEQH QQAQQQQQWP QQQPQMQQEQ WPQQQPQVQQ QQQWPQQQHR RQHGQQQQCM
NSQQQLQQCG QQQQQQLQQQ WSEQQQQQQQ QQWPEQPEQQ QQQQWPEQQQ QQWSDQNQQQ
QAQQWQAQQQ QQWPQQQQQP QQQQQQQQQQ DLGPDGVGIV VPYLGSSPAD FEVQNLGVSV
LPRIKLPLPK FDNDD