LPA2_ARATH
ID LPA2_ARATH Reviewed; 185 AA.
AC F4KDA6; Q0WNZ0; Q9FHN0;
DT 22-JAN-2014, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 25-MAY-2022, entry version 54.
DE RecName: Full=Protein LPA2 {ECO:0000305};
DE AltName: Full=Protein LOW PSII ACCUMULATION 2, chloroplastic {ECO:0000303|PubMed:17601825};
DE Flags: Precursor;
GN Name=LPA2 {ECO:0000303|PubMed:17601825}; OrderedLocusNames=At5g51545;
GN ORFNames=K17N15.9;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10718197; DOI=10.1093/dnares/7.1.31;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence
RT features of the regions of 3,076,755 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:31-63(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 17-185.
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP RETRACTED PAPER.
RX PubMed=17601825; DOI=10.1105/tpc.107.050526;
RA Ma J., Peng L., Guo J., Lu Q., Lu C., Zhang L.;
RT "LPA2 is required for efficient assembly of photosystem II in Arabidopsis
RT thaliana.";
RL Plant Cell 19:1980-1993(2007).
RN [5]
RP RETRACTION NOTICE OF PUBMED:17601825.
RX PubMed=27895223; DOI=10.1105/tpc.16.00881;
RA Ma J., Peng L., Guo J., Lu Q., Lu C., Zhang L.;
RL Plant Cell 28:3061-3061(2016).
RN [6]
RP RETRACTED PAPER.
RX PubMed=20605914; DOI=10.1104/pp.110.159558;
RA Cai W., Ma J., Chi W., Zou M., Guo J., Lu C., Zhang L.;
RT "Cooperation of LPA3 and LPA2 is essential for photosystem II assembly in
RT Arabidopsis.";
RL Plant Physiol. 154:109-120(2010).
RN [7]
RP RETRACTION NOTICE OF PUBMED:20605914.
RX PubMed=28154118; DOI=10.1104/pp.16.01908;
RA Cai W., Ma J., Chi W., Zou M., Guo J., Lu C., Zhang L.;
RL Plant Physiol. 173:1526-1526(2017).
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast membrane {ECO:0000305};
CC Multi-pass membrane protein {ECO:0000255}.
CC -!- CAUTION: A paper reported a role in assisting chlorophyll a binding
CC protein psbC assembly within photosystem II (PSII); however, this paper
CC was later retracted. An article reported an interaction with LPA3;
CC however, this paper was later retracted. {ECO:0000305|PubMed:17601825,
CC ECO:0000305|PubMed:20605914, ECO:0000305|PubMed:27895223,
CC ECO:0000305|PubMed:28154118}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB08670.1; Type=Erroneous gene model prediction; Note=The predicted gene At5g51540 has been split into 2 genes: At5g51540 and At5g51545.; Evidence={ECO:0000305};
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DR EMBL; AB018109; BAB08670.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED96096.1; -; Genomic_DNA.
DR EMBL; AK229296; BAF01159.1; -; mRNA.
DR RefSeq; NP_001032057.1; NM_001036980.3.
DR AlphaFoldDB; F4KDA6; -.
DR STRING; 3702.AT5G51545.1; -.
DR MEROPS; M03.A12; -.
DR iPTMnet; F4KDA6; -.
DR PaxDb; F4KDA6; -.
DR PRIDE; F4KDA6; -.
DR ProteomicsDB; 238496; -.
DR EnsemblPlants; AT5G51545.1; AT5G51545.1; AT5G51545.
DR GeneID; 3771487; -.
DR Gramene; AT5G51545.1; AT5G51545.1; AT5G51545.
DR KEGG; ath:AT5G51545; -.
DR Araport; AT5G51545; -.
DR TAIR; locus:1009023492; AT5G51545.
DR eggNOG; KOG2090; Eukaryota.
DR HOGENOM; CLU_096250_0_0_1; -.
DR InParanoid; F4KDA6; -.
DR OMA; AYGVIKY; -.
DR OrthoDB; 1539512at2759; -.
DR PhylomeDB; F4KDA6; -.
DR PRO; PR:F4KDA6; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; F4KDA6; baseline and differential.
DR Genevisible; F4KDA6; AT.
DR GO; GO:0009507; C:chloroplast; HDA:TAIR.
DR GO; GO:0031969; C:chloroplast membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0009534; C:chloroplast thylakoid; HDA:TAIR.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0009536; C:plastid; HDA:TAIR.
DR InterPro; IPR038789; LPA2-like.
DR PANTHER; PTHR37385; PTHR37385; 1.
PE 2: Evidence at transcript level;
KW Chloroplast; Membrane; Plastid; Reference proteome; Transit peptide;
KW Transmembrane; Transmembrane helix.
FT TRANSIT 1..46
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 47..185
FT /note="Protein LPA2"
FT /id="PRO_0000425142"
FT TRANSMEM 115..135
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 152..172
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 35..105
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 35..72
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 78..105
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 185 AA; 20213 MW; F6C962A7297A2F17 CRC64;
MALQIHSPCS FSTRPYHLFF TTRNPRFAIK CQNSQIESDT TEDPSRSKNS SSSGVGFGSP
ASSSSPAKKL SAATSGNKKG KGKREVNRRA PVEKPVFMSE EGAAKAEEQR QNENAFLLTW
LGLGIVILIE GIILAASGFL PEELDKLFVK YVYPVFTPSV VLFVAGTTAY GVLKYIQNEK
MKGQE
