LPA3_ARATH
ID LPA3_ARATH Reviewed; 358 AA.
AC Q8H0W0; Q8LFG2; Q9SSM1;
DT 22-JAN-2014, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 25-MAY-2022, entry version 104.
DE RecName: Full=Protein LPA3 {ECO:0000305};
DE AltName: Full=Protein LOW PSII ACCUMULATION 3, chloroplastic {ECO:0000303|PubMed:20605914};
DE Flags: Precursor;
GN Name=LPA3 {ECO:0000303|PubMed:20605914}; OrderedLocusNames=At1g73060;
GN ORFNames=F3N23.26;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP RETRACTED PAPER.
RX PubMed=20605914; DOI=10.1104/pp.110.159558;
RA Cai W., Ma J., Chi W., Zou M., Guo J., Lu C., Zhang L.;
RT "Cooperation of LPA3 and LPA2 is essential for photosystem II assembly in
RT Arabidopsis.";
RL Plant Physiol. 154:109-120(2010).
RN [6]
RP RETRACTION NOTICE OF PUBMED:20605914.
RX PubMed=28154118; DOI=10.1104/pp.16.01908;
RA Cai W., Ma J., Chi W., Zou M., Guo J., Lu C., Zhang L.;
RL Plant Physiol. 173:1526-1526(2017).
RN [7]
RP ACETYLATION [LARGE SCALE ANALYSIS] AT GLY-25, CLEAVAGE OF TRANSIT PEPTIDE
RP [LARGE SCALE ANALYSIS] AFTER CYS-24, AND IDENTIFICATION BY MASS
RP SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=22223895; DOI=10.1074/mcp.m111.015131;
RA Bienvenut W.V., Sumpton D., Martinez A., Lilla S., Espagne C., Meinnel T.,
RA Giglione C.;
RT "Comparative large-scale characterisation of plant vs. mammal proteins
RT reveals similar and idiosyncratic N-alpha acetylation features.";
RL Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012).
CC -!- INTERACTION:
CC Q8H0W0; Q84MB2: TIFY8; NbExp=3; IntAct=EBI-25519598, EBI-4426557;
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast
CC {ECO:0000305|PubMed:22223895}.
CC -!- CAUTION: An article reported a role in essential for photosystem II
CC assembly; however, this paper was later retracted.
CC {ECO:0000305|PubMed:20605914, ECO:0000305|PubMed:28154118}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD55653.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC008017; AAD55653.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE35409.1; -; Genomic_DNA.
DR EMBL; BT002009; AAN72020.1; -; mRNA.
DR EMBL; BT008843; AAP68282.1; -; mRNA.
DR EMBL; AY084869; AAM61432.1; -; mRNA.
DR PIR; B96756; B96756.
DR RefSeq; NP_565054.1; NM_105964.5.
DR AlphaFoldDB; Q8H0W0; -.
DR BioGRID; 28856; 3.
DR IntAct; Q8H0W0; 1.
DR STRING; 3702.AT1G73060.1; -.
DR iPTMnet; Q8H0W0; -.
DR PaxDb; Q8H0W0; -.
DR PRIDE; Q8H0W0; -.
DR ProteomicsDB; 238631; -.
DR EnsemblPlants; AT1G73060.1; AT1G73060.1; AT1G73060.
DR GeneID; 843637; -.
DR Gramene; AT1G73060.1; AT1G73060.1; AT1G73060.
DR KEGG; ath:AT1G73060; -.
DR Araport; AT1G73060; -.
DR TAIR; locus:2032662; AT1G73060.
DR eggNOG; ENOG502QW2X; Eukaryota.
DR HOGENOM; CLU_052261_1_0_1; -.
DR InParanoid; Q8H0W0; -.
DR OMA; YIRIRDY; -.
DR OrthoDB; 1610145at2759; -.
DR PhylomeDB; Q8H0W0; -.
DR PRO; PR:Q8H0W0; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q8H0W0; baseline and differential.
DR Genevisible; Q8H0W0; AT.
DR GO; GO:0009507; C:chloroplast; HDA:TAIR.
DR GO; GO:0009570; C:chloroplast stroma; HDA:TAIR.
DR GO; GO:0005739; C:mitochondrion; HDA:TAIR.
DR InterPro; IPR018962; DUF1995.
DR InterPro; IPR044687; LPA3.
DR PANTHER; PTHR34051; PTHR34051; 1.
DR Pfam; PF09353; DUF1995; 1.
PE 1: Evidence at protein level;
KW Acetylation; Chloroplast; Plastid; Reference proteome; Transit peptide.
FT TRANSIT 1..24
FT /note="Chloroplast"
FT /evidence="ECO:0007744|PubMed:22223895"
FT CHAIN 25..358
FT /note="Protein LPA3"
FT /id="PRO_0000425144"
FT MOD_RES 25
FT /note="N-acetylglycine"
FT /evidence="ECO:0007744|PubMed:22223895"
FT CONFLICT 178
FT /note="D -> N (in Ref. 4; AAM61432)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 358 AA; 40029 MW; 003D4CA23B63DA13 CRC64;
MAMAIAMLPA LFSSPSILTS RIRCGATANS GGAISSTSSN SDPRRGVPLY KPKSYEVLAT
DAANSLAFAL QDSKSRLEID FPPLPSSISS YKGSSDDFID ANIQLAVTVV RKLQEKIETR
ACIVFPDKPE KRRASQRFKA AFDSVDGISI GSLDDIPGTS VTNFFRSIRS TLDFDFEDEN
EGTWEPKEPP TLYIFINCST RELSFIEKFV ETFASSTPAL LFNLELDTLR ADLGLLGFPP
KDLHYRFLSQ FIPVFYIRTR EYSKTVAVAP FVLNYNGALF RQYPGPWQVM LKQTDGSFAC
VAESPTRFTL GETKEELLQV LGLQEEKGSS LEFLRRGYKS ATWWEEDVEL EASSNWRN
