LPB1_NEIMA
ID LPB1_NEIMA Reviewed; 419 AA.
AC P57038; A1IP42;
DT 01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2000, sequence version 1.
DT 03-AUG-2022, entry version 87.
DE RecName: Full=Capsule polysaccharide modification protein LipB;
GN Name=lipB; OrderedLocusNames=NMA0185;
OS Neisseria meningitidis serogroup A / serotype 4A (strain DSM 15465 /
OS Z2491).
OC Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC Neisseria.
OX NCBI_TaxID=122587;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15465 / Z2491;
RX PubMed=10761919; DOI=10.1038/35006655;
RA Parkhill J., Achtman M., James K.D., Bentley S.D., Churcher C.M.,
RA Klee S.R., Morelli G., Basham D., Brown D., Chillingworth T., Davies R.M.,
RA Davis P., Devlin K., Feltwell T., Hamlin N., Holroyd S., Jagels K.,
RA Leather S., Moule S., Mungall K.L., Quail M.A., Rajandream M.A.,
RA Rutherford K.M., Simmonds M., Skelton J., Whitehead S., Spratt B.G.,
RA Barrell B.G.;
RT "Complete DNA sequence of a serogroup A strain of Neisseria meningitidis
RT Z2491.";
RL Nature 404:502-506(2000).
CC -!- FUNCTION: Involved in the phospholipid modification of the capsular
CC polysaccharide, a strong requirement for its translocation to the cell
CC surface.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Peripheral
CC membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
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DR EMBL; AL157959; CAM07500.1; -; Genomic_DNA.
DR PIR; G82012; G82012.
DR RefSeq; WP_002233385.1; NC_003116.1.
DR AlphaFoldDB; P57038; -.
DR SMR; P57038; -.
DR EnsemblBacteria; CAM07500; CAM07500; NMA0185.
DR KEGG; nma:NMA0185; -.
DR HOGENOM; CLU_040135_1_0_4; -.
DR OMA; WVFEEGY; -.
DR BioCyc; NMEN122587:NMA_RS00955-MON; -.
DR Proteomes; UP000000626; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR GO; GO:0015774; P:polysaccharide transport; IEA:UniProtKB-KW.
DR InterPro; IPR007833; Capsule_polysaccharide_synth.
DR Pfam; PF05159; Capsule_synth; 1.
PE 4: Predicted;
KW Cell inner membrane; Cell membrane; Membrane; Polysaccharide transport;
KW Sugar transport; Transport.
FT CHAIN 1..419
FT /note="Capsule polysaccharide modification protein LipB"
FT /id="PRO_0000084463"
SQ SEQUENCE 419 AA; 48695 MW; 993175CBF3BE025F CRC64;
MKQTVLKNNL QNLLESAENI LLLQGPVGDF FLRLADWLTA NGKTVHKFNF NAGDDYFYPP
TQAHTVVFND NYDAFPEFLQ EYITQHHIQA VVCFGDTRPY HVIAKRIANE NQASFWAFEE
GYFRPYYITL EKDGVNAFSP LPRRADFFLE QFPKLAQQEY KAPTPVHGGF TPMAKNAIRY
YIELFRNLRK YPDYIHHRAP NAGHYLKPWS LSILKRLNYY IEDIQIAKRV EAGKYGKFFI
VPLQVFNDSQ VRIHCDFPSV RSFLLHVLSS FAEHAPADTN IIIKHHPMDR GFIDYWRDIK
RFIKEHPELK GRVIYVHDVP LPVFLRHGLG MVTINSTSGL SGLIHNMPVK VLGRAYYDIP
GITDQNTLAE FWNHPTPPDK ELFHAYRMYH LNVTQINGNF YSQVFFPNKN TSDSSTPTT