ID   LPCC_RHILV              Reviewed;         352 AA.
AC   O68547;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   25-MAY-2022, entry version 57.
DE   RecName: Full=Lipopolysaccharide core biosynthesis mannosyltransferase LpcC;
DE            EC=2.4.-.-;
GN   Name=lpcC;
OS   Rhizobium leguminosarum bv. viciae.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX   NCBI_TaxID=387;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=3855;
RX   PubMed=9756877; DOI=10.1074/jbc.273.41.26432;
RA   Kadrmas J.L., Allaway D., Studholme R.E., Sullivan J.T., Ronson C.W.,
RA   Poole P.S., Raetz C.R.H.;
RT   "Cloning and overexpression of glycosyltransferases that generate the
RT   lipopolysaccharide core of Rhizobium leguminosarum.";
RL   J. Biol. Chem. 273:26432-26440(1998).
CC   -!- FUNCTION: Acts at transfer of mannose group to a 3-deoxy-D-mono
CC       octulonic acid (KDO) via an alpha-1,5 linkage.
CC   -!- PATHWAY: Bacterial outer membrane biogenesis; LPS core biosynthesis.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase group 1 family.
CC       Glycosyltransferase 4 subfamily. {ECO:0000305}.
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DR   EMBL; AF050103; AAC05215.1; -; Genomic_DNA.
DR   RefSeq; WP_018242997.1; NZ_WIEG01000010.1.
DR   AlphaFoldDB; O68547; -.
DR   SMR; O68547; -.
DR   CAZy; GT4; Glycosyltransferase Family 4.
DR   UniPathway; UPA00958; -.
DR   GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009244; P:lipopolysaccharide core region biosynthetic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR001296; Glyco_trans_1.
DR   Pfam; PF00534; Glycos_transf_1; 1.
PE   3: Inferred from homology;
KW   Glycosyltransferase; Lipopolysaccharide biosynthesis; Transferase.
FT   CHAIN           1..352
FT                   /note="Lipopolysaccharide core biosynthesis
FT                   mannosyltransferase LpcC"
FT                   /id="PRO_0000080296"
SQ   SEQUENCE   352 AA;  38641 MW;  8F3F5CE20C6CE08B CRC64;
     MPDIRDVEII APNFKRRLSG VTSTIVQLIP CQIRLGIKIA TLGPGLPEDL PKLKWRQLLG
     LWRPPARRRR RVWHARRNNE MAVGILLRHL TRMPLKLLFT SAAQRRHTAY TKWLIRRMDA
     VIATSDRSGS FLEVPHTVIQ HGVDLALFHP PEAAEDGIAA TGLPGRHLVG CFGRVRHQKG
     TDLFVRAMIE LLPQHTEWTA VVSGRVTAEH VAFADKLKAD VVAAGLSDRI LFLGEVPDIK
     IWYRRLTLYV APSRNEGFGL TPLEAMASRT AVVASDAGAY AELIVTGETG SVVAASDGEA
     LTRAIAPYIA DPALAVAHGE NALRHVRANF ALEREASAIG AVYNSLLGDN RS