ID   LPER_STRFR              Reviewed;          24 AA.
AC   P45440;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-MAY-2022, entry version 31.
DE   RecName: Full=Erythromycin resistance leader peptide;
DE   AltName: Full=23S rRNA methylase leader peptide;
OS   Streptomyces fradiae (Streptomyces roseoflavus).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=1906;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3127381; DOI=10.1128/jb.170.4.1800-1811.1988;
RA   Kamimiya S., Weisblum B.;
RT   "Translational attenuation control of ermSF, an inducible resistance
RT   determinant encoding rRNA N-methyltransferase from Streptomyces fradiae.";
RL   J. Bacteriol. 170:1800-1811(1988).
CC   -!- FUNCTION: This peptide is involved in the control mechanism of the
CC       synthesis of the macrolide-lincosamide-streptogramin B resistance
CC       protein.
CC   -!- CAUTION: It is uncertain whether Met-1 or Met-3 is the initiator.
CC       {ECO:0000305}.
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DR   EMBL; M19269; AAA26741.1; -; Genomic_DNA.
DR   AlphaFoldDB; P45440; -.
DR   GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
PE   4: Predicted;
KW   Antibiotic resistance; Leader peptide.
FT   PEPTIDE         1..24
FT                   /note="Erythromycin resistance leader peptide"
FT                   /id="PRO_0000043978"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   24 AA;  2529 MW;  756C1635F8C5F06A CRC64;
     MSMGIAARPP RAALLPPPSV PRSR