ID   LPFB_ECO57              Reviewed;         232 AA.
AC   Q8X5K6;
DT   09-JUL-2014, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 2.
DT   25-MAY-2022, entry version 102.
DE   RecName: Full=Probable fimbrial chaperone LpfB;
DE   Flags: Precursor;
GN   Name=lpfB; OrderedLocusNames=Z4969;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   FUNCTION, INDUCTION, AND GENE NAME.
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=12228266; DOI=10.1128/iai.70.10.5416-5427.2002;
RA   Torres A.G., Giron J.A., Perna N.T., Burland V., Blattner F.R.,
RA   Avelino-Flores F., Kaper J.B.;
RT   "Identification and characterization of lpfABCC'DE, a fimbrial operon of
RT   enterohemorrhagic Escherichia coli O157:H7.";
RL   Infect. Immun. 70:5416-5427(2002).
CC   -!- FUNCTION: Part of the lpfABCC'DE fimbrial operon. LP fimbriae may
CC       participate in the interaction with eukaryotic cells by assisting in
CC       microcolony formation. {ECO:0000269|PubMed:12228266}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000250}.
CC   -!- INDUCTION: Induced during the exponential growth phase.
CC       {ECO:0000269|PubMed:12228266}.
CC   -!- SIMILARITY: Belongs to the periplasmic pilus chaperone family.
CC       {ECO:0000305}.
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DR   EMBL; AE005174; AAG58694.1; -; Genomic_DNA.
DR   PIR; B86029; B86029.
DR   PIR; F91182; F91182.
DR   STRING; 155864.EDL933_4810; -.
DR   EnsemblBacteria; AAG58694; AAG58694; Z4969.
DR   KEGG; ece:Z4969; -.
DR   eggNOG; COG3121; Bacteria.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0030288; C:outer membrane-bounded periplasmic space; IEA:InterPro.
DR   GO; GO:0071555; P:cell wall organization; IEA:InterPro.
DR   GO; GO:0061077; P:chaperone-mediated protein folding; IEA:InterPro.
DR   Gene3D; 2.60.40.10; -; 2.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR008962; PapD-like_sf.
DR   InterPro; IPR036316; Pili_assmbl_chap_C_dom_sf.
DR   InterPro; IPR001829; Pili_assmbl_chaperone_bac.
DR   InterPro; IPR016148; Pili_assmbl_chaperone_C.
DR   InterPro; IPR018046; Pili_assmbl_chaperone_CS.
DR   InterPro; IPR016147; Pili_assmbl_chaperone_N.
DR   Pfam; PF02753; PapD_C; 1.
DR   Pfam; PF00345; PapD_N; 1.
DR   PRINTS; PR00969; CHAPERONPILI.
DR   SUPFAM; SSF49354; SSF49354; 1.
DR   SUPFAM; SSF49584; SSF49584; 1.
DR   PROSITE; PS00635; PILI_CHAPERONE; 1.
PE   2: Evidence at transcript level;
KW   Chaperone; Fimbrium biogenesis; Periplasm; Signal.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255"
FT   CHAIN           25..232
FT                   /note="Probable fimbrial chaperone LpfB"
FT                   /id="PRO_0000429484"
SQ   SEQUENCE   232 AA;  25625 MW;  108ECD3C664E99A3 CRC64;
     MDRMMKSKFV ALALSLFLSQ SVLAGGVGLS STRVIYDGSK KEASLTVQNK SKTEEFLIQS
     WVDDAAGSKK TPFIITPPLF KLDPEKNNIL RIVNITPGLP QDRESVYWVN VKAIPSKSDD
     SENKNVLQIA VRTRIKLFYR PAGLKGDVKT APNELRFTRN GNQLRVDNPT VFNITFNQFF
     ANDKEIEKAG MVPAKGALNI TLPAGVGSVS KIKYNTINDF GSXAEMITKN VD