ID   LPFC_SALTY              Reviewed;         842 AA.
AC   P43662;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2002, sequence version 2.
DT   03-AUG-2022, entry version 117.
DE   RecName: Full=Outer membrane usher protein LpfC;
DE   Flags: Precursor;
GN   Name=lpfC; OrderedLocusNames=STM3638;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 14028 / SGSG 2980 / CDC 6516-60 / NCTC 12023;
RX   PubMed=7721701; DOI=10.1128/jb.177.8.2087-2097.1995;
RA   Baeumler A.J., Heffron F.;
RT   "Identification and sequence analysis of lpfABCDE, a putative fimbrial
RT   operon of Salmonella typhimurium.";
RL   J. Bacteriol. 177:2087-2097(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
CC   -!- FUNCTION: Involved in the export and assembly of LpfA fimbrial subunits
CC       across the outer membrane.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the fimbrial export usher family. {ECO:0000305}.
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DR   EMBL; U18559; AAA73968.1; -; Genomic_DNA.
DR   EMBL; AE006468; AAL22498.1; -; Genomic_DNA.
DR   PIR; C56271; C56271.
DR   RefSeq; NP_462539.1; NC_003197.2.
DR   RefSeq; WP_000220312.1; NC_003197.2.
DR   AlphaFoldDB; P43662; -.
DR   SMR; P43662; -.
DR   STRING; 99287.STM3638; -.
DR   PaxDb; P43662; -.
DR   EnsemblBacteria; AAL22498; AAL22498; STM3638.
DR   GeneID; 1255162; -.
DR   KEGG; stm:STM3638; -.
DR   PATRIC; fig|99287.12.peg.3847; -.
DR   HOGENOM; CLU_009120_3_1_6; -.
DR   OMA; QACKTID; -.
DR   PhylomeDB; P43662; -.
DR   BioCyc; SENT99287:STM3638-MON; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015473; F:fimbrial usher porin activity; IBA:GO_Central.
DR   GO; GO:0009297; P:pilus assembly; IBA:GO_Central.
DR   Gene3D; 2.60.40.2070; -; 1.
DR   Gene3D; 2.60.40.2610; -; 1.
DR   Gene3D; 3.10.20.410; -; 1.
DR   InterPro; IPR000015; Fimb_usher.
DR   InterPro; IPR018030; Fimbrial_membr_usher_CS.
DR   InterPro; IPR042186; FimD_plug_dom.
DR   InterPro; IPR025949; PapC-like_C.
DR   InterPro; IPR043142; PapC-like_C_sf.
DR   InterPro; IPR025885; PapC_N.
DR   InterPro; IPR037224; PapC_N_sf.
DR   PANTHER; PTHR30451; PTHR30451; 1.
DR   Pfam; PF13953; PapC_C; 1.
DR   Pfam; PF13954; PapC_N; 1.
DR   Pfam; PF00577; Usher; 1.
DR   SUPFAM; SSF141729; SSF141729; 1.
DR   PROSITE; PS01151; FIMBRIAL_USHER; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Disulfide bond; Fimbrium biogenesis; Membrane;
KW   Reference proteome; Signal; Transmembrane; Transmembrane beta strand;
KW   Transport.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..842
FT                   /note="Outer membrane usher protein LpfC"
FT                   /id="PRO_0000009320"
FT   DISULFID        819..841
FT                   /evidence="ECO:0000255"
FT   CONFLICT        490
FT                   /note="S -> T (in Ref. 1; AAA73968)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        647
FT                   /note="Y -> H (in Ref. 1; AAA73968)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        655..659
FT                   /note="NYGLR -> ELRFG (in Ref. 1; AAA73968)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        689..690
FT                   /note="GA -> AR (in Ref. 1; AAA73968)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        802..803
FT                   /note="PE -> RQ (in Ref. 1; AAA73968)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   842 AA;  92362 MW;  1A91A9A76C38A7B6 CRC64;
     MTWTHLPLGN KTSRFTQSAL ALMIAGTLPA YAGTFNPRFL EDVPGIDQHV DLSMYESNKA
     EHLPGKYRVS VVVNEKKMES RTLEFKAATE AQRAKMGESL VPCLSRVQLE DMGVRIDSFP
     ALKMAPPEAC VAFDDIIPQA ASHFDFADQT LIMSFPQAAM KQTARGTVPE SQWDEGVNAL
     LVDYNFSGSN ASYDAHDSET SYNSDSYYLN LRSGMNLGAW RLRNYSTWTR NDGNNTWDNI
     GTSLSRAIVP LKSQLTLGDT STAGDIFDSV QMRGVQLTSD EEMLPDSQRG FAPVIRGIAK
     SNAEVTVEQN NYVIYRTFVQ PGAFEINDLY PTSNSGDLTV TIKESDGSEQ KFVQPFSSVA
     LLQREGHLKY SLSAGEYRAG NYNSAEPKFG QLDAMYGLPY GFTVYGGAIF SDDYYSLAGG
     LGKNFGYIGA ISIDVTQAKS KLANEENSEG QSYRFLYSKS FNSGTDFRLL GYKYSTSGYY
     TFQEATDVRS DADSSYSQYH KRSQIQGNVT QQLGAWGSVY FNVTQQDYWN DEGKQRSLNA
     GYNGRIGRVN YSVAYTWTKS PEWDESDRLL SFSMSIPLGR VWSNYHLTTD QHGRTNQQLG
     VSGTALEDHN LNYSVQEGYG SNGVGNSGSV NLDYQGGVGS ASLGYNYNRD GQQVNYGLRG
     GVIAHSEGIT LSQPLGESMA IISAPGARGA HVINNGGVEV DWMGNAVVPY LTPYRETEVS
     LRSDSLNNQV DLDTASVNVV PTRGAIVRAR FDTRVGYRVL MNLTQANGKA VPFGATATLL
     DTTKESSSIV GEDGQLYISG MPEKGALQVN WGKDQAQQCR VAFTLPEQQD NTGVVMANAV
     CR